Search Results - "Messer, A"

Frequency of Decreased Susceptibility and Resistance to Echinocandins among Fluconazole-Resistant Bloodstream Isolates of Candida glabrata by PFALLER, M. A, CASTANHEIRA, M, LOCKHART, S. R, AHLQUIST, A. M, MESSER, S. A, JONES, R. N

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Echinocandin and Triazole Antifungal Susceptibility Profiles for Clinical Opportunistic Yeast and Mold Isolates Collected from 2010 to 2011: Application of New CLSI Clinical Breakpoints and Epidemiological Cutoff Values for Characterization of Geographic and Temporal Trends of Antifungal Resistance by Pfaller, Michael A, Messer, Shawn A, Woosley, Leah N, Jones, Ronald N, Castanheira, Mariana

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Analysis of global antifungal surveillance results reveals predominance of Erg11 Y132F alteration among azole-resistant Candida parapsilosis and Candida tropicalis and country-specific isolate dissemination by Castanheira, Mariana, Deshpande, Lalitagauri M., Messer, Shawn A., Rhomberg, Paul R., Pfaller, Michael A.

“…•Antifungal resistance has been slowly increasing among certain yeast species.•Emergence of yeast species with intrinsic resistance to antifungals has been…”
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Differential Activity of the Oral Glucan Synthase Inhibitor SCY-078 against Wild-Type and Echinocandin-Resistant Strains of Candida Species by Pfaller, Michael A, Messer, Shawn A, Rhomberg, Paul R, Borroto-Esoda, Katyna, Castanheira, Mariana

“…SCY-078 (formerly MK-3118) is a novel orally active inhibitor of fungal β-(1,3)-glucan synthase (GS). SCY-078 is a derivative of enfumafungin and is…”
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In Vitro Susceptibility of Invasive Isolates of Candida spp. to Anidulafungin, Caspofungin, and Micafungin: Six Years of Global Surveillance by Pfaller, M.A, Boyken, L, Hollis, R.J, Kroeger, J, Messer, S.A, Tendolkar, S, Diekema, D.J

“…The echinocandins are being used increasingly as therapy for invasive candidiasis. Prospective sentinel surveillance for the emergence of in vitro resistance…”
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Candida Bloodstream Infections: Comparison of Species Distributions and Antifungal Resistance Patterns in Community-Onset and Nosocomial Isolates in the SENTRY Antimicrobial Surveillance Program, 2008-2009 by PFALLER, Michael A, MOET, Gary J, MESSER, Shawn A, JONES, Ronald N, CASTANHEIRA, Mariana

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Candida bloodstream infections: comparison of species distribution and resistance to echinocandin and azole antifungal agents in Intensive Care Unit (ICU) and non-ICU settings in the SENTRY Antimicrobial Surveillance Program (2008–2009) by Pfaller, Michael A, Messer, Shawn A, Moet, Gary J, Jones, Ronald N, Castanheira, Mariana

“…Abstract Minimum inhibitory concentration (MIC) data from the SENTRY Antimicrobial Surveillance Program generated by reference methods were analysed to compare…”
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Geographic Variations in Species Distribution and Echinocandin and Azole Antifungal Resistance Rates among Candida Bloodstream Infection Isolates: Report from the SENTRY Antimicrobial Surveillance Program (2008 to 2009) by Pfaller, Michael A, Moet, Gary J, Messer, Shawn A, Jones, Ronald N, Castanheira, Mariana

“…Antifungal testing results from the SENTRY Antimicrobial Surveillance Program (2008 to 2009) were analyzed for regional variations of invasive Candida species…”
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Activity of a Long-Acting Echinocandin (CD101) and Seven Comparator Antifungal Agents Tested against a Global Collection of Contemporary Invasive Fungal Isolates in the SENTRY 2014 Antifungal Surveillance Program by Pfaller, Michael A, Messer, Shawn A, Rhomberg, Paul R, Castanheira, Mariana

“…The activity of CD101 and comparator antifungal agents against 606 invasive fungal isolates collected worldwide during 2014 was evaluated using the Clinical…”
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In Vitro Activities of Isavuconazole and Comparator Antifungal Agents Tested against a Global Collection of Opportunistic Yeasts and Molds by Pfaller, Michael A, Messer, Shawn A, Rhomberg, Paul R, Jones, Ronald N, Castanheira, Mariana

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Wild-Type MIC Distributions and Epidemiological Cutoff Values for the Echinocandins and Candida spp by Pfaller, M.A, Boyken, L, Hollis, R.J, Kroeger, J, Messer, S.A, Tendolkar, S, Jones, R.N, Turnidge, J, Diekema, D.J

“…We tested a global collection of Candida sp. strains against anidulafungin, caspofungin, and micafungin, using CLSI M27-A3 broth microdilution (BMD) methods,…”
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In Vitro Activity of Seven Systemically Active Antifungal Agents against a Large Global Collection of Rare Candida Species as Determined by CLSI Broth Microdilution Methods by DIEKEMA, D. J, MESSER, S. A, BOYKEN, L. B, HOLLIS, R. J, KROEGER, J, TENDOLKAR, S, PFALLER, M. A

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In Vitro Activity of a New Oral Glucan Synthase Inhibitor (MK-3118) Tested against Aspergillus spp. by CLSI and EUCAST Broth Microdilution Methods by PFALLER, Michael A, MESSER, Shawn A, MOTYL, Mary R, JONES, Ronald N, CASTANHEIRA, Mariana

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Design and Application of a DNA-Encoded Macrocyclic Peptide Library by Zhu, Zhengrong, Shaginian, Alex, Grady, LaShadric C, O’Keeffe, Thomas, Shi, Xiangguo E, Davie, Christopher P, Simpson, Graham L, Messer, Jeffrey A, Evindar, Ghotas, Bream, Robert N, Thansandote, Praew P, Prentice, Naomi R, Mason, Andrew M, Pal, Sandeep

“…A DNA-encoded macrocyclic peptide library was designed and synthesized with 2.4 × 1012 members composed of 4–20 natural and non-natural amino acids…”
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Activity of MGCD290, a Hos2 Histone Deacetylase Inhibitor, in Combination with Azole Antifungals against Opportunistic Fungal Pathogens by Pfaller, M.A, Messer, S.A, Georgopapadakou, N, Martell, L.A, Besterman, J.M, Diekema, D.J

“…We report on the in vitro activity of the Hos2 fungal histone deacetylase (HDAC) inhibitor MGCD290 (MethylGene, Inc.) in combination with azoles against…”
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Geographic Distribution and Antifungal Susceptibility of the Newly Described Species Candida orthopsilosis and Candida metapsilosis in Comparison to the Closely Related Species Candida parapsilosis by Lockhart, Shawn R, Messer, Shawn A, Pfaller, Michael A, Diekema, Daniel J

“…Candida orthopsilosis and Candida metapsilosis are recently described species, having previously been grouped with the more prevalent species Candida…”
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Activity of MK-3118, a new oral glucan synthase inhibitor, tested against Candida spp. by two international methods (CLSI and EUCAST) by Pfaller, Michael A, Messer, Shawn A, Motyl, Mary R, Jones, Ronald N, Castanheira, Mariana

“…To evaluate the activity of the orally bioavailable enfumafungin derivative MK-3118 and comparator antifungal agents tested against a collection of 113…”
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Variation in Candida spp. distribution and antifungal resistance rates among bloodstream infection isolates by patient age: report from the SENTRY Antimicrobial Surveillance Program (2008–2009) by Pfaller, Michael A, Castanheira, Mariana, Messer, Shawn A, Moet, Gary J, Jones, Ronald N

“…Abstract The variation in Candida spp. causing bloodstream infection (BSI) and the frequency of resistance to fluconazole by patient age have been previously…”
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Variation in Susceptibility of Bloodstream Isolates of Candida glabrata to Fluconazole According to Patient Age and Geographic Location in the United States in 2001 to 2007 by Pfaller, M.A, Messer, S.A, Hollis, R.J, Boyken, L, Tendolkar, S, Kroeger, J, Diekema, D.J

“…We examined the susceptibilities to fluconazole of 642 bloodstream infection (BSI) isolates of Candida glabrata and grouped the isolates by patient age and…”
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Antifungal susceptibilities of Candida, Cryptococcus neoformans and Aspergillus fumigatus from the Asia and Western Pacific region: data from the SENTRY antifungal surveillance program (2010–2012) by Pfaller, Michael A, Messer, Shawn A, Jones, Ronald N, Castanheira, Mariana

“…The SENTRY Antifungal Surveillance Program monitors global susceptibility rates of newer and established antifungal agents. We report the in vitro activity of…”
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