Search Results - "Mesquita, S"

Mechanisms and functions of protein S-acylation by S. Mesquita, Francisco, Abrami, Laurence, Linder, Maurine E., Bamji, Shernaz X., Dickinson, Bryan C., van der Goot, F. Gisou

“…Over the past two decades, protein S-acylation (often referred to as S-palmitoylation) has emerged as an important regulator of vital signalling pathways…”
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Simplified 2,4-dinitrophenylhydrazine spectrophotometric assay for quantification of carbonyls in oxidized proteins by Mesquita, Cristina S., Oliveira, Raquel, Bento, Fátima, Geraldo, Dulce, Rodrigues, João V., Marcos, João C.

“…This work proposes a modification of the 2,4-dinitrophenylhydrazine (DNPH) spectrophotometric assay commonly used to evaluate the concentration of carbonyl…”
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SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase by S. Mesquita, Francisco, Abrami, Laurence, Bracq, Lucie, Panyain, Nattawadee, Mercier, Vincent, Kunz, Béatrice, Chuat, Audrey, Carlevaro-Fita, Joana, Trono, Didier, van der Goot, F. Gisou

“…SARS-CoV-2 infection requires Spike protein-mediated fusion between the viral and cellular membranes. The fusogenic activity of Spike depends on its…”
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Fabrication and characterization of a bioactive polymethylmethacrylate‐based porous cement loaded with strontium/calcium apatite nanoparticles by Tomazela, Larissa, Cruz, Marcos Antônio Eufrásio, Nascimento, Larissa Aine, Fagundes, Cecilia C., da Veiga, Márcia Andreia Mesquita S., Zamarioli, Ariane, Bottini, Massimo, Ciancaglini, Pietro, Brassesco, Maria Sol, Engel, Edgard E., Ramos, Ana Paula

“…Polymethylmethacrylate (PMMA)‐based cements are used for bone reparation due to their biocompatibility, suitable mechanical properties, and mouldability…”
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Dynamics of CLIMP-63 S-acylation control ER morphology by Sandoz, Patrick A., Denhardt-Eriksson, Robin A., Abrami, Laurence, Abriata, Luciano A., Spreemann, Gard, Maclachlan, Catherine, Ho, Sylvia, Kunz, Béatrice, Hess, Kathryn, Knott, Graham, S. Mesquita, Francisco, Hatzimanikatis, Vassily, van der Goot, F. Gisou

“…The complex architecture of the endoplasmic reticulum (ER) comprises distinct dynamic features, many at the nanoscale, that enable the coexistence of the…”
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Palmitoylated acyl protein thioesterase APT2 deforms membranes to extract substrate acyl chains by Abrami, Laurence, Audagnotto, Martina, Ho, Sylvia, Marcaida, Maria Jose, Mesquita, Francisco S., Anwar, Muhammad U., Sandoz, Patrick A., Fonti, Giulia, Pojer, Florence, Dal Peraro, Matteo, van der Goot, F. Gisou

“…Many biochemical reactions require controlled recruitment of proteins to membranes. This is largely regulated by posttranslational modifications. A frequent…”
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Seasonal dependent suitability of physical parameterizations to simulate precipitation over the Himalayan headwater by Dixit, Ankur, Sahany, Sandeep, Mishra, Saroj Kanta, Mesquita, Michel D. S.

“…The Himalayan ecosystem is fragile and needs robust management strategies for sustainability of natural resources such as water and vegetation. Therefore,…”
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Effect of Polyplex Size on Penetration into Tumor Spheroids by Casadidio, Cristina, Hartman, Jet E. M., Mesquita, Bárbara S., Haegebaert, Ragna, Remaut, Katrien, Neumann, Myriam, Hak, Jaimie, Censi, Roberta, Di Martino, Piera, Hennink, Wim E., Vermonden, Tina

“…Ovarian cancer is one of the most lethal gynecological cancers in the world. In recent years, nucleic acid (NA)-based formulations have been shown to be…”
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The Impact of Nanobody Density on the Targeting Efficiency of PEGylated Liposomes by Mesquita, Bárbara S, Fens, Marcel H A M, Di Maggio, Alessia, Bosman, Esmeralda D C, Hennink, Wim E, Heger, Michal, Oliveira, Sabrina

“…Nanoparticles (NPs) are commonly modified with tumor-targeting moieties that recognize proteins overexpressed on the extracellular membrane to increase their…”
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Yellow Fever Virus RNA in Urine and Semen of Convalescent Patient, Brazil by Barbosa, Carla M, Di Paola, Nicholas, Cunha, Marielton P, Rodrigues-Jesus, Mônica J, Araujo, Danielle B, Silveira, Vanessa B, Leal, Fabyano B, Mesquita, Flávio S, Botosso, Viviane F, Zanotto, Paolo M A, Durigon, Edison L, Silva, Marcos V, Oliveira, Danielle B L

“…Yellow fever virus RNA is usually detected in blood of infected humans. We detected virus RNA in urine and semen samples from a convalescent patient. A…”
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The Salmonella deubiquitinase SseL inhibits selective autophagy of cytosolic aggregates by Mesquita, Francisco S, Thomas, Mair, Sachse, Martin, Santos, António J M, Figueira, Rita, Holden, David W

“…Cell stress and infection promote the formation of ubiquitinated aggregates in both non-immune and immune cells. These structures are recognised by the…”
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Awake Prone Positioning in COVID‐19 Hypoxemic Respiratory Failure: Exploratory Findings in a Single‐center Retrospective Cohort Study by Padrão, Eduardo M. H., Valente, Fernando S., Besen, Bruno A. M. P., Rahhal, Hassan, Mesquita, Paula S., Alencar, Julio C. G., Costa, Millena G. P., Wanderley, Annelise P. B., Emerenciano, Debora L., Bortoleto, Felipe M., Fortes, Julio C. L., Marques, Bruno, Souza, Stefany F. B., Marchini, Júlio F. M., Neto, Rodrigo A. B., Souza, Heraldo P., Hiestand, Brian

“…Background Awake prone positioning has been widely used in patients with COVID‐19 respiratory failure to avoid intubation despite limited evidence. Our…”
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Persistence and clinical relevance of Zika virus in the male genital tract by Kurscheidt, Fábio A., Mesquita, Cristiane S. S., Damke, Gabrielle M. Z. F., Damke, Edilson, Carvalho, Analine R. B. de A., Suehiro, Tamy T., Teixeira, Jorge J. V., da Silva, Vânia R. S., Souza, Raquel P., Consolaro, Marcia E. L.

“…Zika virus (ZIKV) is a re-emerging mosquito-transmitted flavivirus associated with congenital abnormalities in newborns and with Guillain–Barré syndrome in…”
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Atypical hand-foot-mouth disease in Belém, Amazon region, northern Brazil, with detection of coxsackievirus A6 by Justino, Maria Cleonice A., da S. Mesquita, Deisiane, Souza, Maurício F., Farias, Francisco P., dos S. Alves, Jainara Cristina, Ferreira, James L., Lopes, Daniela P., Tavares, Fernando N.

“…Enterovirus (EV) A71 and coxsackievirus (CV) A16 were the most frequent serotypes involved in hand, foot, and mouth disease (HFMD) outbreaks throughout Asia…”
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Lipocalin-2 regulates adult neurogenesis and contextual discriminative behaviours by Ferreira, A. C., Santos, T., Sampaio-Marques, B., Novais, Ashley Cruz, Mesquita, S. D., Ludovico, Paula, Bernardino, L., Correia-Neves, M, Sousa, Nuno, Palha, Joana Almeida, Sousa, João Carlos, Marques, Fernanda

“…In the adult mammalian brain, newborn granule cells are continuously integrated into hippocampal circuits, and the fine-tuning of this process is important for…”
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Urine Nuclear Magnetic Resonance (NMR) Metabolomics in Age-Related Macular Degeneration by Laíns, Inês, Duarte, Daniela, Barros, António S, Martins, Ana Sofia, Carneiro, Tatiana J, Gil, João Q, Miller, John B, Marques, Marco, Mesquita, Tânia S, Barreto, Patrícia, Kim, Ivana K, da Luz Cachulo, Maria, Vavvas, Demetrios G, Carreira, Isabel M, Murta, Joaquim Neto, Silva, Rufino, Miller, Joan W, Husain, Deeba, Gil, Ana M

“…Biofluid biomarkers of age-related macular degeneration (AMD) are still lacking, and their identification is challenging. Metabolomics is well-suited to…”
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Characteristics and Variability of Storm Tracks in the North Pacific, Bering Sea, and Alaska by Mesquita, Michel D.S., Atkinson, David E., Hodges, Kevin I.

“…The North Pacific and Bering Sea regions represent loci of cyclogenesis and storm track activity. In this paper climatological properties of extratropical…”
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Lipocalin 2 modulates the cellular response to amyloid beta by Mesquita, S D, Ferreira, A C, Falcao, A M, Sousa, J C, Oliveira, T G, Correia-Neves, M, Sousa, N, Marques, F, Palha, J A

“…The production, accumulation and aggregation of amyloid beta (A β ) peptides in Alzheimer’s disease (AD) are influenced by different modulators. Among these…”
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Three-component turbulent velocity fields in the liquid phase of air-water horizontal intermittent pipe flows by Fernandes, Leonardo S., de Mesquita, Rodrigo S. N., Martins, Fabio J. W. A., Azevedo, Luis F. A.

“…•Three component PIV velocity measurements in liquid plug region.•Ensemble-averaged turbulent velocity fields and profiles.•Identification of vortex structures…”
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Effects of retrogressive permafrost thaw slumping on sediment chemistry and submerged macrophytes in Arctic tundra lakes by MESQUITA, PATRÍCIA S, WRONA, FREDERICK J, PROWSE, TERRY D

“…1. Global warming is predicted to cause changes in permafrost cover and stability in the Arctic. Zones of high ion concentration in regions of ice-rich…”
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