Search Results - "Mesitov, Mikhail"
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Poly(A) binding KPAF4/5 complex stabilizes kinetoplast mRNAs in Trypanosoma brucei
Published in Nucleic acids research (04-09-2020)“…Abstract In Trypanosoma brucei, mitochondrial pre-mRNAs undergo 3′-5′ exonucleolytic processing, 3′ adenylation and uridylation, 5′ pyrophosphate removal, and,…”
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2
Pentatricopeptide repeat poly(A) binding protein KPAF4 stabilizes mitochondrial mRNAs in Trypanosoma brucei
Published in Nature communications (11-01-2019)“…In Trypanosoma brucei , most mitochondrial mRNAs undergo editing, and 3′ adenylation and uridylation. The internal sequence changes and terminal extensions are…”
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3
High-throughput mutagenesis identifies mutations and RNA-binding proteins controlling CD19 splicing and CART-19 therapy resistance
Published in Nature communications (22-09-2022)“…Following CART-19 immunotherapy for B-cell acute lymphoblastic leukaemia (B-ALL), many patients relapse due to loss of the cognate CD19 epitope. Since epitope…”
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4
Differential processing of small RNAs during endoplasmic reticulum stress
Published in Scientific reports (13-04-2017)“…The accumulation of misfolded proteins in the endoplasmic reticulum (ER) lumen due to the disruption of the homeostatic system of the ER leads to the induction…”
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5
A rapid protocol for ribosome profiling of low input samples
Published in Nucleic acids research (21-07-2023)“…Abstract Ribosome profiling provides quantitative, comprehensive, and high-resolution snapshots of cellular translation by the high-throughput sequencing of…”
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