Search Results - "Meshnick, S R"

Artemisinin and the antimalarial endoperoxides: from herbal remedy to targeted chemotherapy by Meshnick, S.R. (University of Michigan School of Public Health, Ann Arbor, MI.), Taylor, T.E, Kamchonwongpaisan, S

“…Artemisinin and its derivatives are endoperoxide-containing compounds which represent a promising new class of antimalarial drugs. In the presence of…”
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Impact of maternal malaria and under-nutrition on intrauterine growth restriction: a prospective ultrasound study in Democratic Republic of Congo by LANDIS, S. H., LOKOMBA, V., ANANTH, C. V., ATIBU, J., RYDER, R. W., HARTMANN, K. E., THORP, J. M., TSHEFU, A., MESHNICK, S. R.

“…Maternal malaria and under-nutrition are established risk factors for small-for-gestational-age (SGA) births; however, whether malaria is associated with…”
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Pneumocystis carinii Mutations Are Associated with Duration of Sulfa or Sulfone Prophylaxis Exposure in AIDS Patients by Kazanjian, Powel, Armstrong, Wendy, Hossler, Paul A., Burman, William, Richardson, James, Lee, Chao-Hung, Crane, Lawrence, Katz, Joel, Meshnick, Steven R.

“…This study was conducted to determine whether Pneumocystis carinii dyhydropteroate synthase (DHPS) gene mutations in AIDS patients with P. carinii pneumonia…”
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Uncertain outcomes: adjusting for misclassification in antimalarial efficacy studies by PORTER, K. A., BURCH, C. L., POOLE, C., JULIANO, J. J., COLE, S. R., MESHNICK, S. R.

“…Evaluation of antimalarial efficacy is difficult because recurrent parasitaemia can be due to recrudescence or re-infection. PCR is used to differentiate…”
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Ultrasound‐derived fetal size nomogram for a sub‐Saharan African population: a longitudinal study by Landis, S. H., Ananth, C. V., Lokomba, V., Hartmann, K. E., Thorp, J. M., Horton, A., Atibu, J., Ryder, R. W., Tshefu, A., Meshnick, S. R.

“…Objectives To create a fetal size nomogram for use in sub‐Saharan Africa and compare the derived centiles with reference intervals from developed countries…”
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Iron-dependent free radical generation from the antimalarial agent artemisinin (qinghaosu) by MESHNICK, S. R, YING-ZI YANG, LIMA, V, KUYPERS, F, SUMALEE KAMCHONWONGPAISAN, YONGYUTH YUTHAVONG

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Prevalence of Dihydropteroate Synthase Mutants in HIV-Infected South African Children with Pneumocystis jiroveci Pneumonia by Zar, H. J., Alvarez-Martinez, M. J., Harrison, A., Meshnick, S. R.

“…Background. Pneumocystis jiroveci (formerly Pneumocystis carinii) pneumonia (PCP) is a major cause of mortality in human immunodeficiency virus (HIV)—infected…”
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Reaction of antimalarial endoperoxides with specific parasite proteins by WANIDA ASAWAMAHASAKDA, ITTARAT, I, YU-MING PU, ZIFFER, H, MESHNICK, S. R

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Dihydropteroate Synthase Polymorphisms in Pneumocystis carinii by Lane, Brian R., Ast, Jennifer C., Hossler, Paul A., Mindell, David P., Bartlett, Marilyn S., Smith, James W., Meshnick, Steven R.

“…Sulfa drugs are widely used in the treatment and prophylaxis of Pneumocystis carinii pneumonia…”
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Malaria and Pregnancy: Placental Cytokine Expression and Its Relationship to Intrauterine Growth Retardation by Moormann, Ann M., Sullivan, Amy D., Rochford, Rosemary A., Chensue, Stephen W., Bock, Paul J., Nyirenda, Thomas, Meshnick, Steven R.

“…Malaria infections during pregnancy can lead to the delivery of low-birth-weight infants. In this study, cytokine mRNA was measured in placentas from 23…”
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Field Evaluation of a Real-Time Fluorescence Loop-Mediated Isothermal Amplification Assay, RealAmp, for the Diagnosis of Malaria in Thailand and India by Patel, Jaymin C., Lucchi, Naomi W., Srivastava, Priyanka, Lin, Jessica T., Sug-aram, Rungniran, Aruncharus, Supannee, Bharti, Praveen K., Shukla, Man M., Congpuong, Kanungnit, Satimai, Wichai, Singh, Neeru, Udhayakumar, Venkatachalam, Meshnick, Steven R.

“…Background. To eliminate malaria, surveillance for submicroscopic infections is needed. Molecular methods can detect submicroscopic infections but have not…”
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The Plasmodium falciparum translationally controlled tumor protein homolog and its reaction with the antimalarial drug artemisinin by Bhisutthibhan, J. (University of Michigan, Ann Arbor), Pan, X.Q, Hossler, P.A, Walker, D.J, Yowell, C.A, Carlton, J, Dame, J.B, Meshnick, S.R

“…Artemisinin and its derivatives are important new antimalarial drugs. When Plasmodium falciparum -infected erythrocytes are incubated with [10- 3…”
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Immunoprecipitation of [3H]Dihydroartemisinin Translationally Controlled Tumor Protein (TCTP) Adducts from Plasmodium falciparum-Infected Erythrocytes by Using Anti-TCTP Antibodies by BHISUTTHIBHAN, Jamaree, MESHNICK, Steven R

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Pneumocystis carinii mutations associated with sulfa and sulfone prophylaxis failures in AIDS patients by KAZANJIAN, P, LOCKE, A. B, HOSSLER, P. A, LANE, B. R, BARTLETT, M. S, SMITH, J. W, CANNON, M, MESHNICK, S. R

“…Failures of prophylaxis against Pneumocystis carinii pneumonia (PCP) in AIDS patients do occur, but no evidence for drug resistance has yet been presented. To…”
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Malaria Infection during Pregnancy: Intrauterine Growth Retardation and Preterm Delivery in Malawi by Sullivan, Amy D., Nyirenda, Thomas, Cullinan, Timothy, Taylor, Terrie, Harlow, Sioban D., James, Sherman A., Meshnick, Steven R.

“…In sub-Saharan Africa, malaria infection in pregnancy contributes to low birth weight through intrauterine growth retardation (IUGR) and preterm delivery…”
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Activities and Conformational Fitting of 1,4-Naphthoquinone Derivatives and Other Cyclic 1,4-Diones Tested In Vitro against Pneumocystis carinii by BALL, M. D, BARTLETT, M. S, SHAW, M, SMITH, J. W, NASR, M, MESHNICK, S. R

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Splenic and Hepatic Hemozoin in Mice after Malaria Parasite Clearance by LEVESQUE, M. A, SULLIVAN, A. D, MESHNICK, S. R

“…Hemozoin (malaria pigment) is found in many tissues during malaria infections. In mice that have self-cured from Plasmodium yoelii and Plasmodium chabaudi…”
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Patterns of haemozoin accumulation in tissue by Sullivan, A D, Ittarat, I, Meshnick, S R

“…A sensitive fluorometric method for assaying malarial pigment, haemozoin, has been developed and used to determine the haemozoin content of blood and tissue…”
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Mechanisms of Artemisinin Resistance in the Rodent Malaria Pathogen Plasmodium yoelii by WALKER, D. J, PITSCH, J. L, PENG, M. M, ROBINSON, B. L, PETERS, W, BHISUTTHIBHAN, J, MESHNICK, S. R

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TNF-α promoter single nucleotide polymorphisms are markers of human ancestry by Baena, A, Leung, J Y, Sullivan, A D, Landires, I, Vasquez-Luna, N, Quiñones-Berrocal, J, Fraser, P A, Uko, G P, Delgado, J C, Clavijo, O P, Thim, S, Meshnick, S R, Nyirenda, T, Yunis, E J, Goldfeld, A E

“…We present a map of single nucleotide polymorphisms (SNPs) in the human tumor necrosis factor (TNF)-alpha promoter based upon exploratory sequencing of 333…”
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