Search Results - "Meschini, S"

Corrigendum: Tritium burn efficiency in deuterium–tritium magnetic fusion (2023 Nucl. Fusion 63 126019) by Whyte, D.G., Delaporte-Mathurin, R., Ferry, S.E., Meschini, S.

“…Abstract The controlling parameters regarding tritium burn efficiency (TBE) are derived from first principles and shown to depend fundamentally on the…”
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Tritium burn efficiency in deuterium–tritium magnetic fusion by Whyte, D.G., Delaporte-Mathurin, R., Ferry, S.E., Meschini, S.

“…Abstract The controlling parameters regarding tritium burn efficiency (TBE) are derived from first principles and shown to depend fundamentally on the…”
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TM9SF4 is a novel V-ATPase-interacting protein that modulates tumor pH alterations associated with drug resistance and invasiveness of colon cancer cells by Lozupone, F, Borghi, M, Marzoli, F, Azzarito, T, Matarrese, P, Iessi, E, Venturi, G, Meschini, S, Canitano, A, Bona, R, Cara, A, Fais, S

“…An inverted pH gradient across the cell membranes is a typical feature of malignant cancer cells that are characterized by extracellular acidosis and cytosol…”
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Proton pump inhibition induces autophagy as a survival mechanism following oxidative stress in human melanoma cells by Marino, M L, Fais, S, Djavaheri-Mergny, M, Villa, A, Meschini, S, Lozupone, F, Venturi, G, Della Mina, P, Pattingre, S, Rivoltini, L, Codogno, P, De Milito, A

“…Proton pump inhibitors (PPI) target tumour acidic pH and have an antineoplastic effect in melanoma. The PPI esomeprazole (ESOM) kills melanoma cells through a…”
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Induction and Repair of DNA DSB as Revealed by H2AX Phosphorylation Foci in Human Fibroblasts Exposed to Low- and High-LET Radiation: Relationship with Early and Delayed Reproductive Cell Death by Antonelli, F., Campa, A., Esposito, G., Giardullo, P., Belli, M., Dini, V., Meschini, S., Simone, G., Sorrentino, E., Gerardi, S., Cirrone, G. A. P., Tabocchini, M. A.

“…The spatial distribution of radiation-induced DNA breaks within the cell nucleus depends on radiation quality in terms of energy deposition pattern. It is…”
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The role of free-flowing tributary rivers in the maintenance of genetic diversity of a migratory fish species living in a river fragmented by dams by Ferreira, Dhiego G., Carlsson, Jens, Galindo, Bruno A., Frantine-Silva, Wilson, Apolinário-Silva, Caroline, Meschini, Jéssica S., Zanatta, Augusto S., Almeida, Fernanda S., Sofia, Silvia H.

“…In the neotropics, potamodromous fish species are among the most severely impacted by dams, which can lead to blocking of the migratory routes, elimination of…”
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Autophagy: Molecular mechanisms and their implications for anticancer therapies by Meschini, S, Condello, M, Lista, P, Arancia, G

“…Autophagy is a catabolic process whereby cells maintain homeostasis by eliminating unnecessary proteins and damaged organelles. It may be triggered under…”
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The thiazole derivative CPTH6 impairs autophagy by Ragazzoni, Y, Desideri, M, Gabellini, C, De Luca, T, Carradori, S, Secci, D, Nescatelli, R, Candiloro, A, Condello, M, Meschini, S, Del Bufalo, D, Trisciuoglio, D

“…We have previously demonstrated that the thiazole derivative 3-methylcyclopentylidene-[4-(4′-chlorophenyl)thiazol-2-yl]hydrazone (CPTH6) induces apoptosis and…”
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Autophagy-mediated chemosensitizing effect of the plant alkaloid voacamine on multidrug resistant cells by Meschini, S., Condello, M., Marra, M., Formisano, G., Federici, E., Arancia, G.

“…In our previous studies, voacamine, a bisindolic alkaloid extracted from Peschiera fuchsiaefolia, was examined for its possible capability of enhancing the…”
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Subcellular detection and localization of the drug transporter P-glycoprotein in cultured tumor cells by Molinari, A, Calcabrini, A, Meschini, S, Stringaro, A, Crateri, P, Toccacieli, L, Marra, M, Colone, M, Cianfriglia, M, Arancia, G

“…In vitro studies on the cellular location of P-glycoprotein (Pgp) are reported with the aim to clarify the relationship between its intracellular expression…”
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Role of the lung resistance-related protein (LRP) in the drug sensitivity of cultured tumor cells by Meschini, S., Marra, M., Calcabrini, A., Monti, E., Gariboldi, M., Dolfini, E., Arancia, G.

“…Drug resistance, one of the major obstacle in the successful anticancer therapy, can be observed at the outset of therapy (intrinsic resistance) or after…”
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Voacamine, an alkaloid extracted from Peschiera fuchsiaefolia, inhibits P-glycoprotein action in multidrug-resistant tumor cells by Meschini, S, Marra, M, Condello, M, Calcabrini, A, Federici, E, Dupuis, M L, Cianfriglia, M, Arancia, G

“…Multidrug resistance (MDR) in tumor cells is generally associated with increased efflux of the cytotoxic compounds, due to the activation of mechanisms of…”
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Voacamine, a bisindolic alkaloid from Peschiera fuchsiaefolia, enhances the cytotoxic effect of doxorubicin on multidrug-resistant tumor cells by Meschini, S, Marra, M, Calcabrini, A, Federici, E, Galeffi, C, Arancia, G

“…Multidrug-resistance (MDR) is largely caused by the efflux of therapeutics from the tumor cell by means of P-glycoprotein (P-gp), resulting in reduced efficacy…”
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Intracellular localization of the antitumour drug adriamycin in living cultured cells: a confocal microscopy study by Meschini, S, Molinari, A, Calcabrini, A, Citro, G, Arancia, G

“…The intracellular distribution of the anthracyclinic antibiotic adriamycin in living cultured cells has been investigated by confocal microscopy. In human…”
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Intracellular P-glycoprotein in multidrug resistant tumor cells by Arancia, G, Molinari, A, Calcabrini, A, Meschini, S, Cianfriglia, M

“…The overexpression of the drug-efflux molecular pump P-glycoprotein (P-gp) may confer to tumor cells the multidrug resistant (MDR) phenotype, which is one of…”
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What is the relationship between P-glycoprotein and adhesion molecule expression in melanoma cells? by Molinari, A, Calcabrini, A, Meschini, S, Marra, M, Stringaro, A, Toccacieli, L, Cianfriglia, M, Arancia, G

“…A number of studies have reported that increased P-glycoprotein expression in drug-resistant tumour cells may be associated with decreased expression of a…”
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The cytoskeleton as a subcellular target of the antineoplastic drug lonidamine by Malorni, W, Meschini, S, Matarrese, P, Arancia, G

“…Lonidamine (LND), a dichlorinated derivative of indazole-3-carboxylic acid, has proved to exert a powerful antiproliferative effect and to impair the energy…”
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CD99 inhibits neural differentiation of human Ewing sarcoma cells and thereby contributes to oncogenesis by Rocchi, Anna, Manara, Maria Cristina, Sciandra, Marika, Zambelli, Diana, Nardi, Filippo, Nicoletti, Giordano, Garofalo, Cecilia, Meschini, Stefania, Astolfi, Annalisa, Colombo, Mario P, Lessnick, Stephen L, Picci, Piero, Scotlandi, Katia

“…Ewing sarcoma (EWS) is an aggressive bone tumor of uncertain cellular origin. CD99 is a membrane protein that is expressed in most cases of EWS, although its…”
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Terpinen-4-ol, The Main Component of Melaleuca Alternifolia (Tea Tree) Oil Inhibits the In Vitro Growth of Human Melanoma Cells by Calcabrini, Annarica, Stringaro, Annarita, Toccacieli, Laura, Meschini, Stefania, Marra, Manuela, Colone, Marisa, Arancia, Giuseppe, Molinari, Agnese, Salvatore, Giuseppe, Mondello, Francesca

“…The search for innovative therapeutic approaches based on the use of new substances is gaining more interest in clinical oncology. In this in vitro study the…”
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Lower levels of 1H MRS-visible mobile lipids in H-ras transformed tumorigenic fibroblasts with respect to their untransformed parental cells by Knijn, A, Ferretti, A, Zhang, P J, Giambenedetti, M, Molinari, A, Meschini, S, Pulciani, S, Podo, F

“…High resolution 1H MRS studies report increased mobile neutral lipid (MNL) signals in transformed and malignant as well as in some in vitro cultured embryonic…”
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