Search Results - "Mesa, R."

Spatial organization within a niche as a determinant of stem-cell fate by Rompolas, Panteleimon, Mesa, Kailin R., Greco, Valentina

“…Stem-cell niches in mammalian tissues are often heterogeneous and compartmentalized; however, whether distinct niche locations determine different stem-cell…”
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Homeostatic Epidermal Stem Cell Self-Renewal Is Driven by Local Differentiation by Mesa, Kailin R., Kawaguchi, Kyogo, Cockburn, Katie, Gonzalez, David, Boucher, Jonathan, Xin, Tianchi, Klein, Allon M., Greco, Valentina

“…Maintenance of adult tissues depends on sustained activity of resident stem cell populations, but the mechanisms that regulate stem cell self-renewal during…”
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Spatiotemporal coordination of stem cell commitment during epidermal homeostasis by Rompolas, Panteleimon, Mesa, Kailin R., Kawaguchi, Kyogo, Park, Sangbum, Gonzalez, David, Brown, Samara, Boucher, Jonathan, Klein, Allon M., Greco, Valentina

“…Adult tissues replace lost cells via pools of stem cells. However, the mechanisms of cell self-renewal, commitment, and functional integration into the tissue…”
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Indication and management of allogeneic stem cell transplantation in primary myelofibrosis: a consensus process by an EBMT/ELN international working group by Kröger, N M, Deeg, J H, Olavarria, E, Niederwieser, D, Bacigalupo, A, Barbui, T, Rambaldi, A, Mesa, R, Tefferi, A, Griesshammer, M, Gupta, V, Harrison, C, Alchalby, H, Vannucchi, A M, Cervantes, F, Robin, M, Ditschkowski, M, Fauble, V, McLornan, D, Ballen, K, Popat, U R, Passamonti, F, Rondelli, D, Barosi, G

“…The aim of this work is to produce recommendations on the management of allogeneic stem cell transplantation (allo-SCT) in primary myelofibrosis (PMF). A…”
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Niche-induced cell death and epithelial phagocytosis regulate hair follicle stem cell pool by Mesa, Kailin R., Rompolas, Panteleimon, Zito, Giovanni, Myung, Peggy, Sun, Thomas Y., Brown, Samara, Gonzalez, David G., Blagoev, Krastan B., Haberman, Ann M., Greco, Valentina

“…Mouse hair follicles in the skin cycle between growth and regression, while maintaining a pool of stem cells for continued regeneration; here, live imaging is…”
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Bone marrow fibrosis in myelofibrosis: pathogenesis, prognosis and targeted strategies by Zahr, Abdallah Abou, Salama, Mohamed E, Carreau, Nicole, Tremblay, Douglas, Verstovsek, Srdan, Mesa, Ruben, Hoffman, Ronald, Mascarenhas, John

“…Bone marrow fibrosis is a central pathological feature and World Health Organization major diagnostic criterion of myelofibrosis. Although bone marrow fibrosis…”
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Low JAK2V617F allele burden in primary myelofibrosis, compared to either a higher allele burden or unmutated status, is associated with inferior overall and leukemia-free survival by Tefferi, A, Lasho, T L, Huang, J, Finke, C, Mesa, R A, Li, C Y, Wu, W, Hanson, C A, Pardanani, A

“…The clinical relevance of JAK2 V617F allele burden in primary myelofibrosis (PMF) has not been previously studied. Bone marrow-derived DNA from 199 patients…”
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Alcohol consumption modulates prelimbic cortex response to cocaine following sequential cocaine and alcohol polysubstance use in the rat by Mesa, Javier R, Carter, Emily, Padovan-Hernandez, Yasmin, Knackstedt, Lori A

“…Polysubstance use (PSU), involves the consumption of more than one drug within a period of time and is prevalent among cocaine users. Ceftriaxone, a…”
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A phase-2 trial of low-dose pomalidomide in myelofibrosis by Begna, K H, Mesa, R A, Pardanani, A, Hogan, W J, Litzow, M R, McClure, R F, Tefferi, A

“…In a previous study, we reported on the safety and efficacy of low-dose (0.5 mg) pomalidomide and prednisone and pomalidomide alone (2 mg/day), for the…”
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Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a consensus statement from the international working group for myelofibrosis research and treatment by Barosi, G, Mesa, R A, Thiele, J, Cervantes, F, Campbell, P J, Verstovsek, S, Dupriez, B, Levine, R L, Passamonti, F, Gotlib, J, Reilly, J T, Vannucchi, A M, Hanson, C A, Solberg, L A, Orazi, A, Tefferi, A

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BCL-2 family proteins as 5-Azacytidine-sensitizing targets and determinants of response in myeloid malignancies by Bogenberger, J M, Kornblau, S M, Pierceall, W E, Lena, R, Chow, D, Shi, C-X, Mantei, J, Ahmann, G, Gonzales, I M, Choudhary, A, Valdez, R, Camoriano, J, Fauble, V, Tiedemann, R E, Qiu, Y H, Coombes, K R, Cardone, M, Braggio, E, Yin, H, Azorsa, D O, Mesa, R A, Stewart, A K, Tibes, R

“…Synergistic molecular vulnerabilities enhancing hypomethylating agents in myeloid malignancies have remained elusive. RNA-interference drug modifier screens…”
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Intravital imaging of hair follicle regeneration in the mouse by Pineda, Cristiana M, Park, Sangbum, Mesa, Kailin R, Wolfel, Markus, Gonzalez, David G, Haberman, Ann M, Rompolas, Panteleimon, Greco, Valentina

“…This protocol describes the use of two-photon laser-scanning microscopy (TPLSM) to study hair regeneration within a living, uninjured mouse, enabling…”
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A phase I, open-label, dose-escalation, multicenter study of the JAK2 inhibitor NS-018 in patients with myelofibrosis by Verstovsek, S, Talpaz, M, Ritchie, E, Wadleigh, M, Odenike, O, Jamieson, C, Stein, B, Uno, T, Mesa, R A

“…NS-018 is a Janus-activated kinase 2 (JAK2)-selective inhibitor, targeting the JAK–signal transducer and activator of transcription (STAT) pathway that is…”
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Comparative study of the flexural properties of ABS, PLA and a PLA–wood composite manufactured through fused filament fabrication by Travieso-Rodriguez, J.A, Jerez-Mesa, R, Llumà, Jordi, Gomez-Gras, Giovanni, Casadesus, Oriol

“…Purpose The aim of this paper is to analyze the mechanical properties of acrylonitrile-butadiene-styrene (ABS) parts manufactured through fused filament…”
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Land suitability analysis and water resources for agriculture in semi-arid regions of Andhra Pradesh, South India using remote sensing and GIS techniques by Badapalli, P. K., Kottala, R. B., Madiga, R., Mesa, R.

“…The study of land suitability (LS) for agriculture is one of the most competent mechanisms that show concern for cultivable land and forecasts the supply of…”
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Experimental study of lateral pass width in conventional and vibrations-assisted ball burnishing by Gomez–Gras, G., Travieso–Rodriguez, J. A., Jerez–Mesa, R., Lluma-Fuentes, J., Gomis de la Calle, B.

“…Burnishing is a mechanical finishing operation performed on workpieces to enhance their surface quality through plastic deformation. One of the main issues to…”
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Ruxolitinib versus best available therapy in patients with polycythemia vera: 80-week follow-up from the RESPONSE trial by Verstovsek, Srdan, Vannucchi, Alessandro M, Griesshammer, Martin, Masszi, Tamas, Durrant, Simon, Passamonti, Francesco, Harrison, Claire N, Pane, Fabrizio, Zachee, Pierre, Kirito, Keita, Besses, Carlos, Hino, Masayuki, Moiraghi, Beatriz, Miller, Carole B, Cazzola, Mario, Rosti, Vittorio, Blau, Igor, Mesa, Ruben, Jones, Mark M, Zhen, Huiling, Li, Jingjin, Francillard, Nathalie, Habr, Dany, Kiladjian, Jean-Jacques

“…RESPONSE is an open-label phase 3 study evaluating the Janus kinase 1/Janus kinase 2 inhibitor ruxolitinib versus best available therapy for efficacy/safety in…”
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Evaluation of cerebrospinal fluid proteins as potential biomarkers for early stage Parkinson's disease diagnosis by Dos Santos, Marcia Cristina T, Scheller, Dieter, Schulte, Claudia, Mesa, Irene R, Colman, Peter, Bujac, Sarah R, Bell, Rosie, Berteau, Caroline, Perez, Luis Tosar, Lachmann, Ingolf, Berg, Daniela, Maetzler, Walter, Nogueira da Costa, Andre

“…Cerebrospinal fluid (CSF) has often been used as the source of choice for biomarker discovery with the goal to support the diagnosis of neurodegenerative…”
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Gradual differentiation uncoupled from cell cycle exit generates heterogeneity in the epidermal stem cell layer by Cockburn, Katie, Annusver, Karl, Gonzalez, David G., Ganesan, Smirthy, May, Dennis P., Mesa, Kailin R., Kawaguchi, Kyogo, Kasper, Maria, Greco, Valentina

“…Highly regenerative tissues continuously produce terminally differentiated cells to replace those that are lost. How they orchestrate the complex transition…”
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Comprehensive analysis of surface integrity modification of ball-end milled Ti-6Al-4V surfaces through vibration-assisted ball burnishing by Jerez-Mesa, R., Travieso-Rodríguez, J.A., Landon, Y., Dessein, G., Lluma-Fuentes, J., Wagner, V.

“…[Display omitted] This paper is an experimental research about the mechanical effects on Ti-6Al-4V surfaces treated with an ultrasonic vibration-assisted ball…”
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