Search Results - "Merzouki, Abderrazzak"

Low molecular weight chitosan nanoparticulate system at low N:P ratio for nontoxic polynucleotide delivery by Alameh, Mohamad, Dejesus, Diogo, Jean, Myriam, Darras, Vincent, Thibault, Marc, Lavertu, Marc, Buschmann, Michael D, Merzouki, Abderrazzak

“…Chitosan, a natural polymer, is a promising system for the therapeutic delivery of both plasmid DNA and synthetic small interfering RNA. Reports attempting to…”
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Chitosans for delivery of nucleic acids by Buschmann, Michael D., Merzouki, Abderrazzak, Lavertu, Marc, Thibault, Marc, Jean, Myriam, Darras, Vincent

“…Alternatives to efficient viral vectors in gene therapy are desired because of their poor safety profiles. Chitosan is a promising non-viral nucleotide…”
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T-Cell Receptor-Mediated Anergy of a Human Immunodeficiency Virus (HIV) gp120-Specific CD4+ Cytotoxic T-Cell Clone, Induced by a Natural HIV Type 1 Variant Peptide by Bouhdoud, L, Villain, P, Merzouki, A, Arella, M, Couture, C

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Excess polycation mediates efficient chitosan-based gene transfer by promoting lysosomal release of the polyplexes by Thibault, Marc, Astolfi, Mélina, Tran-Khanh, Nicolas, Lavertu, Marc, Darras, Vincent, Merzouki, Abderrazzak, Buschmann, Michael D

“…Abstract The optimal ratio of the polycation’s amine to DNA phosphate group (N:P) for efficient polymer-based transfection always employs excess polycation…”
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Chitosan-based therapeutic nanoparticles for combination gene therapy and gene silencing of in vitro cell lines relevant to type 2 diabetes by Jean, Myriam, Alameh, Mohamad, De Jesus, Diogo, Thibault, Marc, Lavertu, Marc, Darras, Vincent, Nelea, Monica, Buschmann, Michael D., Merzouki, Abderrazzak

“…Glucagon like peptide 1 (GLP-1), a blood glucose homeostasis modulating incretin, has been proposed for the treatment of type 2 diabetes mellitus (T2DM)…”
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Immobilized carboxymethylated dextran coatings for enhanced ELISA by Liberelle, Benoît, Merzouki, Abderrazzak, Crescenzo, Gregory De

“…We here report the development of a new generation of enzyme-linked immunosorbent assay (ELISA) that takes advantage of a low-fouling carboxymethylated dextran…”
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Chitosanase-based method for RNA isolation from cells transfected with chitosan/siRNA nanocomplexes for real-time RT-PCR in gene silencing by Alameh, Mohamad, Jean, Myriam, Dejesus, Diogo, Buschmann, Michael D, Merzouki, Abderrazzak

“…Chitosan, a well known natural cationic polysaccharide, has been successfully implemented in vitro and in vivo as a nonviral delivery system for both plasmid…”
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Adva-27a, a Novel Podophyllotoxin Derivative Found to Be Effective against Multidrug Resistant Human Cancer Cells by MERZOUKI, Abderrazzak, BUSCHMANN, Michael D, JEAN, Myriam, YOUNG, Rebecca S, LIAO, S. I, GAL, Susannah, LI, Zuomei, SLILATY, Steve N

“…Multidrug resistance poses a serious challenge in cancer therapy. To address this problem, we designed and synthesized Adva-27a, a novel non-ester…”
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New ELISA approach based on coiled-coil interactions by Liberelle, Benoît, Bartholin, Laurence, Boucher, Cyril, Murschel, Frédéric, Jolicoeur, Mario, Durocher, Yves, Merzouki, Abderrazzak, De Crescenzo, Gregory

“…The de novo designed heterodimeric E/K coiled-coil system has been previously demonstrated to be an excellent capture/dimerization system applicable to various…”
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Potential effect of Beauveria bassiana (Hypocreales: Clavicipitaceae) on Anthonomus signatus (Coleoptera: Curculionidae) in strawberries by Sabbahi, Rachid, Merzouki, Aderrazzak, Guertin, Claude

“…The strawberry bud weevil, Anthonomus signatus (Say) (Coleoptera: Curculionidae) is a serious pest of strawberry crops in Canada. The results of previous…”
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HIV-1 gp120/160 expressing transfected cell clones to evaluate the antibody-dependent cellular cytotoxicity (ADCC) during the course of HIV-1 infection by Merzouki, A, Patel, P, Cassol, S, O'Shaughnessy, M, Gill, J, Arella, M

“…Transfection by electroporation of the CEM.NKR cell line with a plasmid containing the HIVNL43 gp160 gene resulted in the establishment of HIV-1 gp120/160…”
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Human immunodeficiency virus type 1 long terminal repeat variants from 42 patients representing all stages of infection display a wide range of sequence polymorphism and transcription activity by Estable, M C, Bell, B, Merzouki, A, Montaner, J S, O'Shaughnessy, M V, Sadowski, I J

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Human immunodeficiency virus type 1 cellular RNA load and splicing patterns predict disease progression in a longitudinally studied cohort by Michael, N L, Mo, T, Merzouki, A, O'Shaughnessy, M, Oster, C, Burke, D S, Redfield, R R, Birx, D L, Cassol, S A

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Identification and characterization of a putative baculoviral transcriptional factor IE-1 from Choristoneura fumiferana granulovirus by Rashidan, Kianoush Khajeh, Nassoury, Nasha, Merzouki, Abderrazzak, Guertin, Claude

“…A gene that encodes a protein homologue to baculoviral IE-1 was identified and sequenced in the genome of the Choristoneura fumiferana granulovirus (ChfuGV)…”
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Molecular characterization of three new avian infectious bronchitis virus (IBV) strains isolated in Quebec by Smati, Ridha, Silim, Amer, Guertin, Claude, Henrichon, Marc, Marandi, Mehdi, Arella, Max, Merzouki, Abderrazzak

“…Three unrecognized field isolates of Infectious Bronchitis Virus (IBV) were recovered from commercial broiler chickens vaccinated with live Mass viral strain…”
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Relation Entre L'activité de la Cytotoxicité Cellulaire Dépendante des Anticorps (ADCC) et la Diversité Génétique Virale: Cohorte Croisée de Patients à Différents Stades de L'infection au VIH-1 by Merzouki, Abderrazzak

“…La variabilité génétique du gène env du VIH-1, et en particulier celle de la région V3, est directement impliquée dans le contrôle du phénotype viral. Le…”
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Accurate and differential quantitation of HIV-1 tat, rev and nef mRNAs by competitive PCR by Merzouki, A, Mo, T, Vellani, N, Pattullo, A, Estable, M, O'Shaughnessy, M, Tsoukas, C, Cassol, S

“…An accurate method is described for measuring the relative abundance of HIV-1 regulatory mRNAs directly in clinical specimens. Specimen RNA is reverse…”
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