Search Results - "Mertz, James R."
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Retinoic acid signals the direction of ocular elongation in the guinea pig eye
Published in Vision research (Oxford) (01-03-2004)“…A growing eye becomes myopic after form deprivation (FD) or compensates for the power and sign of imposed spectacle lenses. A possible mediator of the…”
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Change in the Synthesis Rates of Ocular Retinoic Acid and Scleral Glycosaminoglycan during Experimentally Altered Eye Growth in Marmosets
Published in Investigative ophthalmology & visual science (01-05-2006)“…The purpose of this study was to examine the possibility that all-trans-retinoic acid (RA) in the eye is a signal related to changes in scleral extracellular…”
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Acute effects of dietary retinoic acid on ocular components in the growing chick
Published in Experimental eye research (01-10-2006)“…When the eyes of chicks are induced to grow toward myopia or hyperopia by having them wear spectacle lenses or diffusers, opposite changes take place in the…”
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Biochemical properties, tissue expression, and gene structure of a short chain dehydrogenase/ reductase able to catalyze cis-retinol oxidation
Published in Journal of lipid research (01-12-1999)“…We have identified a retinol dehydrogenase (cRDH) that catalyzes the oxidation of 9-cis- but not all-trans-retinol and proposed that this enzyme plays an…”
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Characterization of a New Member of the Fatty Acid-binding Protein Family That Binds All-trans-retinol
Published in The Journal of biological chemistry (12-01-2001)“…Cellular retinol-binding protein, type I (CRBP-I) and type II (CRBP-II) are the only members of the fatty acid-binding protein (FABP) family that process…”
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Identification of Two Regions in Apolipoprotein B100 That Are Exposed on the Cytosolic Side of the Endoplasmic Reticulum Membrane
Published in The Journal of cell biology (04-05-1998)“…Protease protection assays of apolipoprotein B100 (apoB) in digitonin-permeabilized HepG2 cells indicated that multiple domains of apoB are exposed to the…”
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Identification and Characterization of a Stereospecific Human Enzyme That Catalyzes 9-cis-Retinol Oxidation
Published in The Journal of biological chemistry (02-05-1997)“…All- trans - and 9- cis -retinoic acid are active retinoids for regulating expression of retinoid responsive genes, serving as ligands for two classes of…”
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Choroidal Retinoic Acid Synthesis: A Possible Mediator between Refractive Error and Compensatory Eye Growth
Published in Experimental eye research (01-04-2000)“…Research over the past two decades has shown that the growth of young eyes is guided by vision. If near-or far-sightedness is artificially imposed by spectacle…”
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Cellular retinoic acid- and cellular retinol-binding proteins: complementary deoxyribonucleic acid cloning, chromosomal assignment, and tissue specific expression
Published in Molecular endocrinology (Baltimore, Md.) (01-08-1987)“…Both cellular retinoic acid-binding protein (CRABP) and cellular retinol-binding protein (CRBP) are widely distributed in mammalian tissues and display…”
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Identification and characterization of a stereospecific human enzyme that catalyzes 9-cis-retinol oxidation. A possible role in 9-cis-retinoic acid formation
Published in The Journal of biological chemistry (02-05-1997)“…All-trans- and 9-cis-retinoic acid are active retinoids for regulating expression of retinoid responsive genes, serving as ligands for two classes of…”
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Purification, partial characterization, and localization of Sak57, an acidic intermediate filament keratin present in rat spermatocytes, spermatids, and sperm
Published in Molecular reproduction and development (01-07-1996)“…We have purified a 57 kDa protein (designated Sak57, for spermatogenic cell/sperm‐associated keratin) from sodium dodecyl…”
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Substrate specificities and 13- cis-retinoic acid inhibition of human, mouse and bovine cis-retinol dehydrogenases
Published in Biochimica et biophysica acta (03-01-2000)“…Recent studies of the human, mouse and bovine genes for 11- cis-retinol dehydrogenase (11cRDH) and human and mouse 9- cis-retinol dehydrogenase (9cRDH) suggest…”
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Rat sperm galactosyl receptor: purification and identification by polyclonal antibodies raised against multiple antigen peptides
Published in Molecular reproduction and development (01-07-1995)“…We have previously reported the purification of rats testis galactosyl receptor, an equivalent to the Ca(2+)-dependent (C-type) minor variant of rat hepatic…”
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Localization of retinoid binding proteins, retinoid receptors, and retinaldehyde dehydrogenase in the chick eye
Published in Brain cell biology (01-07-1999)“…Retinoids have many functions in the eye, including, perhaps, the visual guidance of ocular growth. Therefore, we identified where retinoid receptors, binding…”
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Rat Sertoli and spermatogenic cells express a similar gene, and its product is antigenically related to an outer dense fiber-associated protein
Published in Molecular reproduction and development (01-12-1992)“…We have previously reported that a heterodimeric protein secreted by rat Sertoli cells is antigenically related to a protein associated with outer dense fibers…”
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Localization of retinoid binding proteins, retinoid receptors, and retinaldehyde dehydrogenase in the chick eye
Published in Journal of neurocytology (01-07-1999)“…Retinoids have many functions in the eye, including, perhaps, the visual guidance of ocular growth. Therefore, we identified where retinoid receptors, binding…”
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