Search Results - "Mertens, W. C"

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    Gemcitabine in advanced renal cell carcinoma. A phase II study of the National Cancer Institute of Canada Clinical Trials Group by Mertens, W C, Eisenhauer, E A, Moore, M, Venner, P, Stewart, D, Muldal, A, Wong, D

    Published in Annals of oncology (01-04-1993)
    “…Gemcitabine (2', 2'-difluorodeoxycytidine; dFdC) an anticancer agent with activity in preclinical models, was felt to be a promising new chemotherapy drug…”
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    Journal Article
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    Systemic bone-seeking radionuclides for palliation of painful osseous metastases: current concepts by Mertens, W. C, Filipczak, L. A, Ben-Josef, E, Davis, L. P, Porter, A. T

    Published in CA: a cancer journal for clinicians (01-11-1998)
    “…Bone metastases require multidisciplinary treatment, the primary goal of which is to relieve pain and improve quality of life. Among the options available,…”
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    Journal Article
  3. 3

    Radionuclide therapy of bone metastases: prospects for enhancement of therapeutic efficacy by Mertens, W C

    Published in Seminars in oncology (01-06-1993)
    “…Systemically administered, beta-emitting radionuclides provide effective pain relief for many patients with symptomatic osseous metastases. Unfortunately,…”
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    Journal Article
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    Metastatic melanoma from intraocular primary tumors: The Southwest Oncology Group experience in phase II advanced melanoma clinical trials by FLAHERTY, L. E, UNGER, J. M, LIU, P. Y, MERTENS, W. C, SONDAK, V. K

    Published in American journal of clinical oncology (01-12-1998)
    “…Ocular melanoma is an uncommon malignancy that, in the presence of metastatic disease, has a poor prognosis for response to treatment and survival. Patients…”
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    Journal Article
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    Docetaxel in advanced renal carcinoma. A phase II trial of the National Cancer Institute of Canada Clinical Trials Group by Mertens, W C, Eisenhauer, E A, Jolivet, J, Ernst, S, Moore, M, Muldal, A

    Published in Annals of oncology (01-02-1994)
    “…Most patients diagnosed with renal carcinoma developed metastatic disease at some time during their course, with available therapy inducing response in only a…”
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    Journal Article
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    Effect of indomethacin plus ranitidine in advanced melanoma patients on high-dose interleukin-2 by Mertens, W C, Bramwell, V H, Gwadry-Sridhar, F, Romano, W, Banerjee, D, Lala, P K

    Published in The Lancet (British edition) (15-08-1992)
    “…Preclinical models of advanced melanoma have shown that chronic indomethacin therapy combined with interleukin 2 (IL-2) can eradicate experimental metastases…”
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    Journal Article
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    Strontium 89 therapy and relief of pain in patients with prostatic carcinoma metastatic to bone: a dose response relationship? by Mertens, W C, Stitt, L, Porter, A T

    Published in American journal of clinical oncology (01-06-1993)
    “…Reports published in the English literature of clinical trials utilizing intravenous strontium 89 (89Sr) in the treatment of patients with prostatic…”
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    Journal Article
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    Glutathione S-transferase expression in renal cell carcinoma: a new marker of differentiation by Grignon, D J, Abdel-Malak, M, Mertens, W C, Sakr, W A, Shepherd, R R

    Published in Modern pathology (01-02-1994)
    “…Expression of two GST isoenzymes (alpha and pi) was assessed immunohistochemically in 46 cases of renal cell carcinoma (RCC) for which clinical follow-up was…”
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    Journal Article
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    Oral indomethacin and ranitidine in advanced melanoma: A phase II study by Mertens, W.C., Lohmann, R.C.

    “…As a result of preclinical data demonstrating the antitumour and antimetastatic efficiency of indomethacin in murine models, and the clinical observation of…”
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    Journal Article Conference Proceeding
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    Adjuvant chemotherapy in the treatment of soft-tissue sarcoma by Mertens, W C, Bramwell, V H

    Published in Clinical orthopaedics and related research (01-04-1993)
    “…Standard therapy for treatment of soft-tissue sarcoma dictates adequate surgical resection with or without radiation therapy. However, metastases occur in a…”
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    Journal Article
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    Adjuvant chemotherapy for soft tissue sarcomas by Mertens, W C, Bramwell, V H

    “…Despite considerable interest in this subject and the completion of a number of randomized trials, the use of adjuvant chemotherapy after definitive local…”
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    Journal Article
  13. 13

    Strontium-89 and Low-Dose Infusion Cisplatin for Patients with Hormone Refractory Prostate Carcinoma Metastatic to Bone: A Preliminary Report by Mertens, Wilson C, Porter, Arthur T, Reid, Robert H, Powe, John E

    Published in The Journal of nuclear medicine (1978) (01-08-1992)
    “…Strontium-89 has been used for the treatment of painful bony metastases in patients suffering from disseminated adenocarcinoma of the prostate, with a variable…”
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    Journal Article
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    Malignant paraganglioma with skeletal metastases and spinal cord compression: response and palliation with chemotherapy by Mertens, W C, Grignon, D J, Romano, W

    “…Paragangliomas (carotid body tumours, chemodectomas) may arise in any area of the body where sympathetic ganglia are present, including chemoreceptors, the…”
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    Journal Article
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    Differential aspects of sleep epilepsy by Young, G B, Blume, W T, Wells, G A, Mertens, W C, Eder, S

    Published in Canadian journal of neurological sciences (01-11-1985)
    “…A review of patients with epilepsy showed that 5.9% had seizures exclusively in sleep (ES) and 4.7% had seizures predominantly but not exclusively in sleep…”
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    Osteosarcoma and other tumors of bone by Mertens, Wilson C, Bramwell, Vivien

    Published in Current opinion in oncology (01-07-1994)
    “…Steady progress has been made in the identification of genetic alterations and prognostic factors in osteosarcoma. Imaging studies continue to be employed not…”
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    Journal Article
  17. 17

    Osteosarcoma and other tumors of bone by Mertens, Wilson C, Bramwell, Vivien

    Published in Current opinion in oncology (01-07-1995)
    “…Although no major advances in local or systemic therapy have been reported, further progress has been made in the identification of genetic alterations and…”
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    Journal Article
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    Sustained oral indomethacin and ranitidine with intermittent continuous infusion interleukin-2 in advanced renal cell carcinoma by Mertens, W C, Bramwell, V H, Banerjee, D, Gwadry-Sridhar, F, al-Mutter, N, Parhar, R S, Lala, P K

    Published in Cancer biotherapy (1993)
    “…Experimental work in murine models has shown that, during the development of tumors, prostaglandin E2 produced by host macrophages inactivates natural killer…”
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    Journal Article