Search Results - "Mertens, Freya"
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An autophagy-driven pathway of ATP secretion supports the aggressive phenotype of BRAFV600E inhibitor-resistant metastatic melanoma cells
Published in Autophagy (02-09-2017)“…The ingrained capacity of melanoma cells to rapidly evolve toward an aggressive phenotype is manifested by their increased ability to develop drug-resistance,…”
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2
Regeneration in the Pituitary After Cell-Ablation Injury: Time-Related Aspects and Molecular Analysis
Published in Endocrinology (Philadelphia) (01-02-2016)“…We recently showed that the mouse pituitary holds regenerative competence. Young-adult GHCre/iDTR mice, expressing diphtheria toxin (DT) receptor in…”
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3
Intra-patient and inter-metastasis heterogeneity of HER2-low status in metastatic breast cancer
Published in European journal of cancer (1990) (01-07-2023)“…Anti-HER2 antibody-drug conjugates (ADCs) have shown important efficacy in HER2-low metastatic breast cancer (mBC). Criteria for receiving ADCs are based on a…”
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4
Exploring stem cell biology in pituitary tumors and derived organoids
Published in Endocrine-related cancer (01-07-2022)“…Pituitary tumorigenesis is highly prevalent and causes major endocrine disorders. Hardly anything is known on the behavior of the local stem cells in this…”
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5
Pituitary tumors contain a side population with tumor stem cell-associated characteristics
Published in Endocrine-related cancer (01-08-2015)“…Pituitary adenomas cause significant endocrine and mass-related morbidity. Little is known about the mechanisms that underlie pituitary tumor pathogenesis. In…”
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6
Integration of Pathological Criteria and Immunohistochemical Evaluation for Invasive Lobular Carcinoma Diagnosis: Recommendations From the European Lobular Breast Cancer Consortium
Published in Modern pathology (01-07-2024)“…Invasive lobular carcinoma (ILC) is the second most frequent type of breast cancer (BC) and its peculiar morphology is mainly driven by inactivation of CDH1,…”
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7
Notch system is differentially expressed and activated in pituitary adenomas of distinct histotype, tumor cell lines and normal pituitaries
Published in Oncotarget (22-08-2017)“…Pituitary adenomas are among the most frequent intracranial neoplasms and treatment depends on tumor subtype and clinical features. Unfortunately, non…”
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8
An autophagy-driven pathway of ATP secretion supports the aggressive phenotype of BRAF V600E inhibitor-resistant metastatic melanoma cells
Published in Autophagy (02-09-2017)“…The ingrained capacity of melanoma cells to rapidly evolve toward an aggressive phenotype is manifested by their increased ability to develop drug-resistance,…”
Get full text
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9
Abstract HER2-16: HER2-16 Inter-lesion heterogeneity of HER2-status in metastatic breast cancer: possible implications for treatment with anti-HER2 antibody-drug conjugates
Published in Cancer research (Chicago, Ill.) (01-03-2023)“…Abstract Background. Trastuzumab deruxtecan (T-DXd) has shown promising activity in patients with HER2-low metastatic breast cancer. As the HER2-status can…”
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10
Pulmonary inflammation in mice with collagen‐induced arthritis is conditioned by complete Freund's adjuvant and regulated by endogenous IFN‐γ
Published in European journal of immunology (01-12-2012)“…Following immunization with collagen II (CII) in complete Freund's adjuvant (CFA), DBA/1 mice develop arthritis of major joints. This collagen‐induced…”
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11
Pulmonary inflammation in mice with collagen-induced arthritis is conditioned by complete Freund's adjuvant and regulated by endogenous IFN-[gamma]
Published in European journal of immunology (01-12-2012)“…Following immunization with collagen II (CII) in complete Freund's adjuvant (CFA), DBA/1 mice develop arthritis of major joints. This collagen-induced…”
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Journal Article -
12
Pulmonary inflammation in mice with collagen‐induced arthritis is conditioned by complete F reund's adjuvant and regulated by endogenous IFN ‐γ
Published in European journal of immunology (01-12-2012)“…Following immunization with collagen II ( C II) in complete F reund's adjuvant ( CFA ), DBA /1 mice develop arthritis of major joints. This collagen‐induced…”
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13
Pulmonary inflammation in mice with collagen-induced arthritis is conditioned by complete F reund's adjuvant and regulated by endogenous IFN -[gamma]
Published in European journal of immunology (01-12-2012)“…Following immunization with collagen II ( C II) in complete F reund's adjuvant ( CFA ), DBA /1 mice develop arthritis of major joints. This collagen-induced…”
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