Search Results - "Merten, C. A."

Combi-seq for multiplexed transcriptome-based profiling of drug combinations using deterministic barcoding in single-cell droplets by Mathur, L., Szalai, B., Du, N. H., Utharala, R., Ballinger, M., Landry, J. J. M., Ryckelynck, M., Benes, V., Saez-Rodriguez, J., Merten, C. A.

“…Anti-cancer therapies often exhibit only short-term effects. Tumors typically develop drug resistance causing relapses that might be tackled with drug…”
Get full text

Drop-based microfluidic devices for encapsulation of single cells by Köster, Sarah, Angilè, Francesco E, Duan, Honey, Agresti, Jeremy J, Wintner, Anton, Schmitz, Christian, Rowat, Amy C, Merten, Christoph A, Pisignano, Dario, Griffiths, Andrew D, Weitz, David A

“…We use microfluidic devices to encapsulate, incubate, and manipulate individual cells in picoliter aqueous drops in a carrier fluid at rates of up to several…”
Get more information

Fusoselect: cell–cell fusion activity engineered by directed evolution of a retroviral glycoprotein by Merten, Christoph A., Stitz, Jörn, Braun, Gundula, Medvedovska, Julia, Cichutek, Klaus, Buchholz, Christian J.

“…Membrane fusion plays a key role in many biological processes including vesicle trafficking, synaptic transmission, fertilization or cell entry of enveloped…”
Get full text

Modulation of Phase Shift between Wnt and Notch Signaling Oscillations Controls Mesoderm Segmentation by Sonnen, Katharina F., Lauschke, Volker M., Uraji, Julia, Falk, Henning J., Petersen, Yvonne, Funk, Maja C., Beaupeux, Mathias, François, Paul, Merten, Christoph A., Aulehla, Alexander

“…How signaling dynamics encode information is a central question in biology. During vertebrate development, dynamic Notch signaling oscillations control…”
Get full text

A competition-based assay for the screening of species-specific antibiotics by Granieri, Lucia, Miller, Oliver J., Griffiths, Andrew D., Merten, Christoph A.

“…Objectives To develop a high throughput screening-compatible assay for the selection of species-specific antibiotics that do not harm human cells. Methods…”
Get full text

Circumventing Tolerance to the Prion Protein (PrP): Vaccination with PrP-Displaying Retrovirus Particles Induces Humoral Immune Responses against the Native Form of Cellular PrP by NIKLES, Daphne, BACH, Patricia, BOLLER, Klaus, MERTEN, Christoph A, MONTRASIO, Fabio, HEPPNER, Frank L, AGUZZI, Adriano, CICHUTEK, Klaus, KALINKE, Ulrich, BUCHHOLZ, Christian J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Directed Evolution of Retrovirus Envelope Protein Cytoplasmic Tails Guided by Functional Incorporation into Lentivirus Particles by MERTEN, Christoph A, STITZ, Jörn, BRAUN, Gundula, POESCHLA, Eric M, CICHUTEK, Klaus, BUCHHOLZ, Christian J

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Displaying Epidermal Growth Factor on Spleen Necrosis Virus-Derived Targeting Vectors by Merten, Christoph A., Engelstaedter, Martin, Buchholz, Christian J., Cichutek, Klaus

“…Targeted gene transfer into human cells has previously been achieved with spleen necrosis virus (SNV)-derived vector particles harboring envelope (Env)…”
Get full text