Search Results - "Merry, T. L."

Mitochondria-targeted antioxidant supplementation improves 8 km time trial performance in middle-aged trained male cyclists by Broome, S C, Braakhuis, A J, Mitchell, C J, Merry, T L

“…Exercise increases skeletal muscle reactive oxygen species (ROS) production, which may contribute to the onset of muscular fatigue and impair athletic…”
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Voluntary resistance wheel exercise during post-natal growth in rats enhances skeletal muscle satellite cell and myonuclear content at adulthood by Smith, H. K., Merry, T. L.

“…Aim:  To determine whether voluntary free wheel (FW) or resistance wheel (RW) exercise or reduced muscle activity would influence maturational increases in…”
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Effects of aerobic fitness on hypohydration-induced physiological strain and exercise impairment by Merry, T.L, Ainslie, P.N, Cotter, J.D

“…Hypohydration exacerbates cardiovascular and thermal strain and can impair exercise capacity in temperate and warm conditions. Yet, athletes often dehydrate in…”
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Dietary supplementation of clinically utilized PI3K p110α inhibitor extends the lifespan of male and female mice by Hedges, C P, Shetty, B, Broome, S C, MacRae, C, Koutsifeli, P, Buckels, E J, MacIndoe, C, Boix, J, Tsiloulis, T, Matthews, B G, Sinha, S, Arendse, M, Jaiswal, J K, Mellor, K M, Hickey, A J R, Shepherd, P R, Merry, T L

“…Diminished insulin and insulin-like growth factor-1 signaling extends the lifespan of invertebrates ; however, whether it is a feasible longevity target in…”
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T cell protein tyrosine phosphatase (TCPTP) deficiency in muscle does not alter insulin signalling and glucose homeostasis in mice by Loh, K., Merry, T. L., Galic, S., Wu, B. J., Watt, M. J., Zhang, S., Zhang, Z.-Y., Neel, B. G., Tiganis, T.

“…Aims/hypothesis Insulin activates insulin receptor protein tyrosine kinase and downstream phosphatidylinositol-3-kinase (PI3K)/Akt signalling in muscle to…”
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Local hindlimb antioxidant infusion does not affect muscle glucose uptake during in situ contractions in rat by MERRY, T. L, DYWER, R. M, BRADLEY, E. A, RATTIGAN, S, MCCONELL, G. K

“…There is evidence that reactive oxygen species (ROS) contribute to the regulation of skeletal muscle glucose uptake during highly fatiguing ex vivo contraction…”
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Peripheral blood mononuclear cells do not reflect skeletal muscle mitochondrial function or adaptation to high-intensity interval training in healthy young men by Hedges, C P, Woodhead, J S T, Wang, H W, Mitchell, C J, Cameron-Smith, D, Hickey, A J R, Merry, T L

“…Measurement of skeletal muscle mitochondrial respiration requires invasive biopsy to obtain a muscle sample. Peripheral blood mononuclear cell (PBMC)…”
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S‐Glutathionylation of troponin I (fast) increases contractile apparatus Ca2+ sensitivity in fast‐twitch muscle fibres of rats and humans by Mollica, J. P., Dutka, T. L., Merry, T. L., Lamboley, C. R., McConell, G. K., McKenna, M. J., Murphy, R. M., Lamb, G. D.

“…Key points  •  Reactive oxygen‐based molecules generated within muscle fibres in both exercise and pathological conditions can greatly affect muscle function…”
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MitoQ supplementation augments acute exercise-induced increases in muscle PGC1α mRNA and improves training-induced increases in peak power independent of mitochondrial content and function in untrained middle-aged men by Broome, S.C., Pham, T., Braakhuis, A.J., Narang, R., Wang, H.W., Hickey, A.J.R., Mitchell, C.J., Merry, T.L.

“…The role of mitochondrial ROS in signalling muscle adaptations to exercise training has not been explored in detail. We investigated the effect of…”
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Do reactive oxygen species regulate skeletal muscle glucose uptake during contraction? by Merry, Troy L, McConell, Glenn K

“…The mechanisms regulating skeletal muscle glucose uptake during contraction remain poorly defined. Recent studies suggest reactive oxygen species may be an…”
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S ‐Glutathionylation of troponin I (fast) increases contractile apparatus Ca 2+ sensitivity in fast‐twitch muscle fibres of rats and humans by Mollica, J. P., Dutka, T. L., Merry, T. L., Lamboley, C. R., McConell, G. K., McKenna, M. J., Murphy, R. M., Lamb, G. D.

“…Key points  Reactive oxygen‐based molecules generated within muscle fibres in both exercise and pathological conditions can greatly affect muscle function…”
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