Search Results - "Merry, B"
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1
Parallel, Realistic and Controllable Terrain Synthesis
Published in Computer graphics forum (01-05-2015)“…The challenge in terrain synthesis for virtual environments is to provide a combination of precise user control over landscape form, with interactive response…”
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2
Molecular mechanisms linking calorie restriction and longevity
Published in International Journal of Biochemistry and Cell Biology (01-11-2002)“…Calorie-restricted feeding retards the rate of ageing in mammalian and invertebrate species. The molecular mechanisms underlying this effect include a lower…”
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3
Oxidative stress and mitochondrial function with aging – the effects of calorie restriction
Published in Aging cell (01-02-2004)“…Summary Accumulated oxidative stress resulting from a gradual shift in the redox status of tissues is now considered to be a key mechanism underlying the aging…”
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Effect of caloric restriction on mitochondrial reactive oxygen species production and bioenergetics: reversal by insulin
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-01-2004)“…To gain insight into the antiaging mechanisms of caloric restriction (CR), mitochondria from liver tissue of male Brown Norway rats were used to study the…”
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Assembly of the Elongin A Ubiquitin Ligase Is Regulated by Genotoxic and Other Stresses
Published in The Journal of biological chemistry (12-06-2015)“…Elongin A performs dual functions in cells as a component of RNA polymerase II (Pol II) transcription elongation factor Elongin and as the substrate…”
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Cockayne syndrome B protein regulates recruitment of the Elongin A ubiquitin ligase to sites of DNA damage
Published in The Journal of biological chemistry (21-04-2017)“…Elongin A performs dual functions as the transcriptionally active subunit of RNA polymerase II (Pol II) elongation factor Elongin and as the substrate…”
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Evaluation of non-reducing end pathologic glycosaminoglycan detection method for monitoring therapeutic response to enzyme replacement therapy in human mucopolysaccharidosis I
Published in Molecular genetics and metabolism (01-02-2020)“…Therapeutic development and monitoring require demonstration of effects on disease phenotype. However, due to the complexity of measuring clinically-relevant…”
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Safety of laronidase delivered into the spinal canal for treatment of cervical stenosis in mucopolysaccharidosis I
Published in Molecular genetics and metabolism (01-09-2015)“…Enzyme replacement therapy with laronidase (recombinant human alpha-l-iduronidase) is successfully used to treat patients with mucopolysaccharidosis type I…”
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9
The home environment and toddler physical activity: an ecological momentary assessment study
Published in Pediatric obesity (01-02-2017)“…Summary Background Physical activity (PA) promotion/obesity prevention in toddlerhood should include home environments. Objective The aim of the study was to…”
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The molecular basis by which dietary restricted feeding reduces mitochondrial reactive oxygen species generation
Published in Mechanisms of ageing and development (2011)“…▶ The paper explains why mitochondria from DR rats generate lower rates of mitochondrial H 2O 2. ▶ Enhanced proton leak through the ANT induces mild uncoupling…”
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Specific antibody titer alters the effectiveness of intrathecal enzyme replacement therapy in canine mucopolysaccharidosis I
Published in Molecular genetics and metabolism (01-05-2012)“…Intrathecal enzyme replacement therapy is an experimental option to treat central nervous system disease due to lysosomal storage. Previous work shows that MPS…”
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12
Dietary restriction in rodents—delayed or retarded ageing?
Published in Mechanisms of ageing and development (01-09-2005)“…Dietary restriction (DR) feeding increases survival significantly in strains of rats and mice. There remains however, the question as to whether these two…”
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Arterial pathology in canine mucopolysaccharidosis-I and response to therapy
Published in Laboratory investigation (01-05-2011)“…Mucopolysaccharidosis-I (MPS-I) is an inherited deficiency of α-L-iduronidase (IdU) that causes lysosomal accumulation of glycosaminoglycans (GAG) in a variety…”
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14
Early versus late treatment of spinal cord compression with long-term intrathecal enzyme replacement therapy in canine mucopolysaccharidosis type I
Published in Molecular genetics and metabolism (01-10-2010)“…Enzyme replacement therapy (ERT) with intravenous recombinant human alpha-l-iduronidase (IV rhIDU) is a treatment for patients with mucopolysaccharidosis I…”
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Calorie Restriction and Age-Related Oxidative Stress
Published in Annals of the New York Academy of Sciences (01-06-2000)“…: Calorie restriction (CR) in mammals has been recognized as the best characterized and most reproducible strategy for extending maximum survival, retarding…”
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Amelioration of renal cortex histological alterations by aqueous garlic extract in gentamicin induced renal toxicity in albino rats: a histological and immunohistochemical study
Published in Alexandria journal of medicine (01-01-2021)“…Background: Aminoglycosides, particularly gentamicin, endure crucial antibiotics in the armamentarium for severe Gram-negative bacterial infections through…”
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The effect of aging and caloric restriction on mitochondrial protein density and oxygen consumption
Published in Experimental gerontology (01-03-2004)“…It has been proposed that part of the anti-aging mechanism of caloric restriction (CR) involves changes in mitochondrial function. To investigate this…”
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18
Simplifying Character Skins with Analytic Error Metrics
Published in Computer graphics forum (01-03-2010)“…Traditionally, levels of detail (LOD) for animated characters are computed from a single pose. Later techniques refined this approach by considering a set of…”
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Faster GPU-based convolutional gridding via thread coarsening
Published in Astronomy and computing (01-07-2016)“…Convolutional gridding is a processor-intensive step in interferometric imaging. While it is possible to use graphics processing units (GPUs) to accelerate…”
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Lack of Effect of Caloric Restriction on Bioenergetics and Reactive Oxygen Species Production in Intact Rat Hepatocytes
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (01-02-2005)“…To investigate the hypothesis that caloric restriction alters mitochondrial function in situ, intact hepatocytes were isolated from fully fed and…”
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