Search Results - "Merron, Andrew"

Targeted Radionuclide Therapy Using a Wnt-Targeted Replicating Adenovirus Encoding the Na/I Symporter by Peerlinck, Inge, Merron, Andrew, Baril, Patrick, Conchon, Sophie, Martin-Duque, Pilar, Hindorf, Cécilia, Burnet, Jerome, Quintanilla, Miguel, Hingorani, Mohan, Iggo, Richard, Lemoine, Nick R, Harrington, Kevin, Vassaux, Georges

“…Purpose: The Na/I symporter (hNIS) promotes concentration of iodine in cells. In cancer gene therapy, this transgene has potential as a reporter gene for…”
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Cancer-specific transgene expression mediated by systemic injection of nanoparticles by Chisholm, Edward J, Vassaux, Georges, Martin-Duque, Pilar, Chevre, Raphael, Lambert, Olivier, Pitard, Bruno, Merron, Andrew, Weeks, Mark, Burnet, Jerome, Peerlinck, Inge, Dai, Ming-Shen, Alusi, Ghassan, Mather, Stephen J, Bolton, Katherine, Uchegbu, Ijeoma F, Schatzlein, Andreas G, Baril, Patrick

“…The lack of safe and efficient systemic gene delivery vectors has largely reduced the potential of gene therapy in the clinic. Previously, we have reported…”
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Modulation of telomerase promoter tumor selectivity in the context of oncolytic adenoviruses by BILSLAND, Alan E, MERRON, Andrew, VASSAUX, Georges, KEITH, W. Nicol

“…The telomerase RNA (hTR) and reverse transcriptase (hTERT) promoters are active in most cancer cells, but not in normal cells, and are useful for…”
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Radiation-Mediated Up-Regulation of Gene Expression from Replication-Defective Adenoviral Vectors: Implications for Sodium Iodide Symporter Gene Therapy by HINGORANI, Mohan, WHITE, Christine L, VASSAUX, Georges, HARRINGTON, Kevin J, ZAIDI, Shane, MERRON, Andrew, PEERLINCK, Inge, GORE, Martin E, NUTTING, Christopher M, PANDHA, Hardev S, MELCHER, Alan A, VILE, Richard G

“…Purpose: To assess the effects of external beam radiotherapy (EBRT) on adenoviral-mediated transgene expression in vitro and in vivo and to define an optimal…”
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Assessment of the Na/I symporter as a reporter gene to visualize oncolytic adenovirus propagation in peritoneal tumours by Merron, Andrew, Baril, Patrick, Martin-Duque, Pilar, de la Vieja, Antonio, Tran, Lucile, Briat, Arnaud, Harrington, Kevin J., McNeish, Iain A., Vassaux, Georges

“…Purpose In vivo imaging of the spread of oncolytic viruses using the Na/I symporter (NIS) has been proposed. Here, we assessed whether the presence of NIS in…”
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Inhibition of repair of radiation-induced DNA damage enhances gene expression from replication-defective adenoviral vectors by Hingorani, Mohan, White, Christine L, Merron, Andrew, Peerlinck, Inge, Gore, Martin E, Slade, Andrew, Scott, Simon D, Nutting, Christopher M, Pandha, Hardev S, Melcher, Alan A, Vile, Richard G, Vassaux, Georges, Harrington, Kevin J

“…Radiation has been shown to up-regulate gene expression from adenoviral vectors in previous studies. In the current study, we show that radiation-induced dsDNA…”
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Cancer-Specific Transgene Expression Mediated by Systemic injection of Nanoparticies by CHISHOLM, EdwardJ, VASSAUX, Georges, DAI, Ming-Shen, ALUSI, Ghassan, MATHER, Stephen J, BOLTON, Katherine, UCHEGBU, Ijeoma F, SCHATZLEIN, Andreas G, BARIL, Patrick, MARTIN-DUQUE, Pilar, CHEVRE, Raphael, LAMBERT, Olivier, PITARD, Bruno, MERRON, Andrew, WEEKS, Mark, BURNET, Jerome, PEERLINCK, Inge

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