Search Results - "Merritt, Kate"
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Longitudinal Structural MRI Findings in Individuals at Genetic and Clinical High Risk for Psychosis: A Systematic Review
Published in Frontiers in psychiatry (02-02-2021)“…Several cross-sectional studies report brain structure differences between healthy volunteers and subjects at genetic or clinical high risk of developing…”
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The Sander parallelogram illusion dissociates action and perception despite control for the litany of past confounds
Published in Cortex (01-01-2018)“…The two visual systems hypothesis proposes that human vision is supported by an occipito-temporal network for the conscious visual perception of the world and…”
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Relationship between Glutamate Dysfunction and Symptoms and Cognitive Function in Psychosis
Published in Frontiers in psychiatry (26-11-2013)“…The glutamate hypothesis of schizophrenia, proposed over two decades ago, originated following the observation that administration of drugs that block NMDA…”
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Caring for refugees and asylum seekers in Canada: Early experiences and comprehensive global health training for medical students
Published in Canadian medical education journal (01-12-2020)Get full text
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Relationship between brain glutamate levels and clinical outcome in individuals at ultra high risk of psychosis
Published in Neuropsychopharmacology (New York, N.Y.) (01-11-2014)“…Alterations in brain glutamate levels may be associated with psychosis risk, but the relationship to clinical outcome in at-risk individuals is unknown…”
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White Matter Microstructure Abnormalities in Individuals at High Risk for Psychosis: A Meta-Analysis of Fractional Anisotropic Changes Associated With Transition to Psychosis
Published in BJPsych open (01-06-2024)“…Aims Recent studies have focussed on detecting white matter abnormalities in subjects who transition to psychosis (UHR-T). Research suggests that fractional…”
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Effects of Antipsychotic Administration on Brain Glutamate in Schizophrenia: A Systematic Review of Longitudinal 1H-MRS Studies
Published in Frontiers in psychiatry (28-04-2017)“…Schizophrenia is associated with brain glutamate dysfunction, but it is currently unclear whether antipsychotic administration can reduce the extent of…”
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Automatic Online Motor Control Is Intact in Parkinson's Disease With and Without Perceptual Awareness
Published in eNeuro (01-09-2017)“…In the double-step paradigm, healthy human participants automatically correct reaching movements when targets are displaced. Motor deficits are prominent in…”
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165. Nature of Glutamate Alterations in Schizophrenia: A Meta-Analysis of Proton Magnetic Resonance Spectroscopy Studies
Published in Schizophrenia bulletin (01-03-2017)“…Background: Alterations in glutamatergic neurotransmission may be fundamental to the pathophysiology of schizophrenia and the glutamatergic system may be a…”
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Nature of Glutamate Alterations in Schizophrenia: A Meta-analysis of Proton Magnetic Resonance Spectroscopy Studies
Published in JAMA psychiatry (Chicago, Ill.) (01-07-2016)“…Alterations in glutamatergic neurotransmission may be fundamental to the pathophysiology of schizophrenia, and the glutamatergic system is a target for novel…”
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Remission from antipsychotic treatment in first episode psychosis related to longitudinal changes in brain glutamate
Published in NPJ schizophrenia (01-08-2019)“…Neuroimaging studies in schizophrenia have linked elevated glutamate metabolite levels to non-remission following antipsychotic treatment, and also indicate…”
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Variability and Magnitude of Brain Glutamate Levels in Schizophrenia: A Meta and Mega-Analysis
Published in Biological psychiatry (1969) (15-05-2024)Get full text
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Dopamine and glutamate in individuals at high risk for psychosis: a meta‐analysis of in vivo imaging findings and their variability compared to controls
Published in World psychiatry (01-10-2021)“…Dopaminergic and glutamatergic dysfunction is believed to play a central role in the pathophysiology of schizophrenia. However, it is unclear if abnormalities…”
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A Longitudinal Study of Head Circumference Trajectories in Autism and Autistic Traits
Published in Journal of autism and developmental disorders (12-10-2024)“…Increased head circumference is an established finding in autism spectrum disorder (ASD); however, it is unclear when this increase occurs, if it persists and…”
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Association of Age, Antipsychotic Medication, and Symptom Severity in Schizophrenia With Proton Magnetic Resonance Spectroscopy Brain Glutamate Level: A Mega-analysis of Individual Participant-Level Data
Published in JAMA psychiatry (Chicago, Ill.) (01-06-2021)“…Proton magnetic resonance spectroscopy (1H-MRS) studies indicate that altered brain glutamatergic function may be associated with the pathophysiology of…”
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T40. GLYCERYL TRINITRATE IN FIRST EPISODE PSYCHOSIS UNMEDICATED WITH ANTIPSYCHOTICS: A RANDOMISED CONTROLLED FEASIBILITY STUDY
Published in Schizophrenia bulletin (18-05-2020)“…Abstract Background There is a pressing need for new classes of treatment for psychosis. A key therapeutic target for novel compounds is the NMDA receptor,…”
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Glyceryl trinitrate in first-episode psychosis unmedicated with antipsychotics: A randomised controlled pilot study
Published in Journal of psychopharmacology (Oxford) (01-08-2020)“…Background: There is a pressing need for new classes of treatment for psychosis. A key therapeutic target for novel compounds is the NMDA receptor, which may…”
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Exploring causal mechanisms of psychosis risk
Published in Neuroscience and biobehavioral reviews (01-07-2024)“…Robust epidemiological evidence of risk and protective factors for psychosis is essential to inform preventive interventions. Previous evidence syntheses have…”
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The impact of cumulative obstetric complications and childhood trauma on brain volume in young people with psychotic experiences
Published in Molecular psychiatry (01-09-2023)“…Psychotic experiences (PEs) occur in 5–10% of the general population and are associated with exposure to childhood trauma and obstetric complications. However,…”
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Molecular and micro-architectural mapping of gray matter alterations in psychosis
Published in Molecular psychiatry (12-09-2024)“…The psychosis spectrum encompasses a heterogeneous range of clinical conditions associated with abnormal brain development. Detecting patterns of atypical…”
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