Search Results - "Merritt, Andrew"

Peptidomimetic analogues of an Arg-Trp-x-x-Trp motif responsible for interaction of translocase MraY with bacteriophage ϕX174 lysis protein E by Kerr, Rachel V., Fairbairn, Julia A., Merritt, Andrew T., Bugg, Timothy D.H.

“…[Display omitted] Translocase MraY is the target for bacteriophage ϕX174 lysis protein E, which interacts via a protein–protein interaction mediated by Phe-288…”
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Collaborative practices for medicinal chemistry research across the big pharma and not-for-profit interface by Andrews, David M., Swarbrick, Martin E., Merritt, Andrew T.

“…•Many global research groups are using collaborative medicinal chemistry to derisk early portfolios.•The opportunities and issues in inter-organizational…”
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Gluteal-Sparing Approach for Posterior Iliac Crest Bone Graft: Description of a New Technique and Assessment of Morbidity in Ninety-Two Patients After Spinal Fusion by MERRITT, Andrew L, SPINNICKE, Anthony, PETTIGREW, Kate, ALAMIN, Todd F

“…Retrospective clinical series. Description of alternative technique for the harvesting of posterior iliac crest bone graft (ICBG) and assessment of associated…”
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A combined geomorphological and geophysical approach to characterising relict landslide hazard on the Jurassic Escarpments of Great Britain by Boon, David P., Chambers, Jonathan E., Hobbs, Peter R.N., Kirkham, Mathew, Merritt, Andrew J., Dashwood, Claire, Pennington, Catherine, Wilby, Philip R.

“…The Jurassic Escarpment in the North York Moors in Northern Britain has a high density of deep-seated relict landslides but their regional hazard is poorly…”
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Hand Injuries in Rock Climbing by Merritt, Andrew L., MD, Huang, Jerry I., MD

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A cleavable linker strategy for optimising enolate alkylation reactions of a polymer-supported Evans' oxazolidin-2-one by Green, Rachel, Merritt, Andrew T, Bull, Steven D

“…A cleavable linker strategy has been used to optimise the enolate alkylation reactions of a recyclable L-tyrosine derived polymer-supported oxazolidin-2-one…”
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The clerodane ring system: investigating the viability of a direct Diels-Alder approach by Merritt, Andrew T, Pouwer, Rebecca H, Williams, David J, Williams, Craig M, Ley, Steven V

“…A direct synthetic approach to the spiro-γ-lactone clerodane ring system has been investigated. This work builds on that of Jung and highlights the inherent…”
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Prospective, Double-Blind, Randomized, Placebo-Controlled Comparison of Acetazolamide Versus Ibuprofen for Prophylaxis Against High Altitude Headache: The Headache Evaluation at Altitude Trial (HEAT) by Gertsch, Jeffrey H., Lipman, Grant S., Holck, Peter S., Merritt, Andrew, Mulcahy, Allison, Fisher, Robert S., Basnyat, Buddha, Allison, Eric, Hanzelka, Keeli, Hazan, Alberto, Meyers, Zachary, Odegaard, Justin, Pook, Benjamin, Thompson, Mark, Slomovic, Brant, Wahlberg, Henrik, Wilshaw, Vanessa, Weiss, Eric A., Zafren, Ken

“…Objective High altitude headache (HAH) is the most common neurological complaint at altitude and the defining component of acute mountain sickness (AMS)…”
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Dihydropyrancarboxamides Related to Zanamivir:  A New Series of Inhibitors of Influenza Virus Sialidases. 1. Discovery, Synthesis, Biological Activity, and Structure−Activity Relationships of 4-Guanidino- and 4-Amino-4H-pyran-6-carboxamides by Smith, Paul W, Sollis, Steven L, Howes, Peter D, Cherry, Peter C, Starkey, Ian D, Cobley, Kevin N, Weston, Helen, Scicinski, Jan, Merritt, Andrew, Whittington, Andrew, Wyatt, Paul, Taylor, Neil, Green, Darren, Bethell, Richard, Madar, Safia, Fenton, Robert J, Morley, Peter J, Pateman, Tony, Beresford, Alan

“…4-Amino- and 4-guanidino-4H-pyran-6-carboxamides 4 and 5 related to zanamivir (GG167) are a new class of inhibitors of influenza virus sialidases…”
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Rationale and Treatment of Multiple-Ligament Injured Knees: The Seattle Perspective by Merritt, Andrew L., MD, Wahl, Christopher J., MD

“…The senior author (CJW) is the primary surgeon for the management of multiple-ligament knee injuries at Harborview Medical Center and the University of…”
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Myth: blood transfusion is effective for sickle cell anemia-associated priapism by Merritt, Andrew L, Haiman, Christopher, Henderson, Sean O

“…Priapism is a recognized complication of sickle cell anemia (SCA). When initial conventional treatments fail, simple or exchange blood transfusion has been…”
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Pituitary Disorders by Owolabi, Mark, Malone, Michael, Merritt, Andrew

“…In this article, we will review common pituitary disorders. There are 6 hormones secreted by the anterior pituitary gland: thyroid-stimulating hormone,…”
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Thyroid Disorders by Dhir, Gauri, Jain, Vasudha, Merritt, Andrew

“…This article includes a review of information primary care physicians need to know direct their evaluation and treatment of thyroid disorders that include sick…”
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Combinatorial chemistry: Rumors of the demise of combinatorial chemistry are greatly exaggerated by Merritt, Andrew T, Gerritz, Samuel W

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Mountain Sickness Knowledge Among Foreign Travelers in Cuzco, Peru by Merritt, Andrew L, Camerlengo, Anne, Meyer, Carinne, Mull, J. Dennis

“…Category 1 Continuing Medical Education credit for physicians is available to Wilderness Medical Society members for this article. Go to…”
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Setting a Long Story Straight: Attic εὐθύς ‘straight’, Ionic ῑθύς ‘id.’, and Vedic sādhú- ‘id.’ by Merritt, Andrew

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Prognostic Factors for Bacterial Cultures Positive for Propionibacterium acnes and Other Organisms in a Large Series of Revision Shoulder Arthroplasties Performed for Stiffness, Pain, or Loosening by Pottinger, Paul, Butler-Wu, Susan, Neradilek, Moni Blazej, Merritt, Andrew, Bertelsen, Alexander, Jette, Jocelyn L, Warme, Winston J, Matsen, Frederick A

“…BACKGROUND:Propionibacterium acnes has been grown on culture in half of the reported cases of chronic infection associated with shoulder arthroplasty. The…”
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Four‐dimensional imaging of moisture dynamics during landslide reactivation by Uhlemann, Sebastian, Chambers, Jonathan, Wilkinson, Paul, Maurer, Hansruedi, Merritt, Andrew, Meldrum, Philip, Kuras, Oliver, Gunn, David, Smith, Alister, Dijkstra, Tom

“…Landslides pose significant risks to communities and infrastructure, and mitigating these risks relies on understanding landslide causes and triggering…”
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Uptake of new technology in lead optimization for drug discovery by Merritt, Andrew T

“…The arrival of combinatorial chemistry in pharmaceutical lead optimization has usually been greeted with reservation by chemists at the bench—it isn't what…”
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Maximizing Planter Potential: An Analysis of the Church Planter Assessment of The Wesleyan Church by Merritt, Andrew W

“…Since the mid 1980s, efforts have been made by church leaders across denominations within the United States to assess the potential of a prospective church…”
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