Search Results - "Merrill, JE"

Cytokines in inflammatory brain lesions: helpful and harmful by Merrill, Jean E., Benveniste, Etty N.

“…Multiple sclerosis (MS) is thought to be an autoimmune disease. In healthy individuals, the T cells of the immune system, when activated by an infectious…”
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Proinflammatory and antiinflammatory cytokines in multiple sclerosis and central nervous system acquired immunodeficiency syndrome by Merrill, J E

“…While certain cytokines such as interleukin-1 (IL-1), tumor necrosis factor-alpha (TNF-alpha), IL-6, and transforming growth factor-beta (TGF-beta) may be…”
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Risk Factors for Driving After and During Marijuana Use by Aston, Elizabeth R, Merrill, Jennifer E, McCarthy, Denis M, Metrik, Jane

“…Use of marijuana before or while driving significantly contributes to driving impairment and elevated risk of motor vehicle accidents; however, this risk…”
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Is the pregame to blame? Event-level associations between pregaming and alcohol-related consequences by Merrill, Jennifer E, Vermont, Leah N, Bachrach, Rachel L, Read, Jennifer P

“…Pregaming (drinking before a social occasion) predicts alcohol consequences between persons; people who pregame report greater consequences than those who do…”
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Beyond the “Binge” threshold: Heavy drinking patterns and their association with alcohol involvement indices in college students by Read, Jennifer P, Beattie, Melissa, Chamberlain, Rebecca, Merrill, Jennifer E

“…Abstract Despite its ubiquity, the term “Binge” drinking has been controversial. Among other things, the grouping of drinkers into a single risk category based…”
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Complementary patterns of gene expression by human oligodendrocyte progenitors and their environment predict determinants of progenitor maintenance and differentiation by Sim, Fraser J., Lang, Jennifer K., Waldau, Ben, Roy, Neeta S., Schwartz, Theodore E., Pilcher, Webster H., Chandross, Karen J., Natesan, Sridaran, Merrill, Jean E., Goldmanm, Steven A.

“…Objective Glial progenitor cells are abundant in adult human white matter. This study was designed to identify signaling pathways regulating their self‐renewal…”
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In vitro study of mediators of inflammation in multiple sclerosis by MERRILL, J. E, STROM, S. R, ELLISON, G. W, MYERS, L. W

“…Prostaglandin E levels have previously been demonstrated to be elevated in multiple sclerosis (MS). We have further investigated other products of activated…”
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Microglial cell cytotoxicity of oligodendrocytes is mediated through nitric oxide by Merrill, JE, Ignarro, LJ, Sherman, MP, Melinek, J, Lane, TE

“…Rat ameboid microglia are able to lyse rat oligodendrocytes in vitro. The lysis is inhibited by transforming growth factor-beta, antagonists of nitric oxide…”
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Differential expression, cytokine modulation, and specific functions of type-1 and type-2 tumor necrosis factor receptors in rat glia by Dopp, Joel M, Mackenzie-Graham, Allan, Otero, Glen C, Merrill, Jean E

“…Tumor necrosis factor alpha (TNF α) and lymphotoxin alpha (LT α) induce pleiotropic cellular effects through low-affinity 55 kDa type-1 receptors (TNFR1,…”
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Inflammatory Events at the Blood Brain Barrier: Regulation of Adhesion Molecules, Cytokines, and Chemokines by Reactive Nitrogen and Oxygen Species by Merrill, Jean E., Murphy, Seán P.

“…Recruitment of inflammatory cells into the CNS during pathological processes associated with neurodegeneration, trauma, autoimmune disease, and infection…”
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HIV-1, macrophages, glial cells, and cytokines in AIDS nervous system disease by Merrill, J E, Chen, I S

“…Hallmarks of central nervous system (CNS) disease in AIDS patients are headaches, fever, subtle cognitive changes, abnormal reflexes, and ataxia. Dementia and…”
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Intercellular signaling in glial cells: calcium waves and oscillations in response to mechanical stimulation and glutamate by Charles, A C, Merrill, J E, Dirksen, E R, Sanderson, M J

“…Intercellular Ca2+ signaling in primary cultures of glial cells was investigated with digital fluorescence video imaging. Mechanical stimulation of a single…”
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Nitric oxide as a potential pathological mechanism in demyelination: its differential effects on primary glial cells in vitro by Mitrovic, B, Ignarro, L J, Montestruque, S, Smoll, A, Merrill, J E

“…Because we believe that macrophage-derived nitric oxide contributes to pathology of demyelinating diseases, we have determined the differential effects of…”
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Tumor necrosis factor alpha, interleukin 1 and related cytokines in brain development: normal and pathological by Merrill, J E

“…Microglia and astrocytes produce several cytokines including interleukin 1 (IL1) and tumor necrosis factor alpha (TNF alpha), which have pleiotropic effects in…”
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Mechanisms of damage to myelin and oligodendrocytes and their relevance to disease by MERRILL, J. E, SCOLDING, N. J

“…Oligodendrocytes synthesize and maintain myelin in the central nervous system (CNS). Damage may occur to these cells in a number of conditions, including…”
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Interactions of the nervous and immune systems in development, normal brain homeostasis, and disease by Merrill, J E, Jonakait, G M

“…Neurotransmitters, neuropeptides, neurotrophins, and neuroendocrine hormones have traditionally been assigned functions in normal development and homeostasis…”
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Inducible nitric-oxide synthase and nitric oxide production in human fetal astrocytes and microglia. A kinetic analysis by Ding, M, St Pierre, B A, Parkinson, J F, Medberry, P, Wong, J L, Rogers, N E, Ignarro, L J, Merrill, J E

“…The understanding of the induction and regulation of inducible nitric-oxide synthase (iNOS) in human cells may be important in developing therapeutic…”
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Photosynthetic inorganic carbon utilization and growth of Porphyra linearis (Rhodophyta) by ISRAEL, A, KATZ, S, DUBINSKY, Z, MERRILL, J. E, FRIEDLANDER, M

“…Photosynthetic (oxygen evolution) and growth (biomass increase) responses to ambient pH and inorganic carbon (Ci) supply were determined for Porphyra linearis…”
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Tumor necrosis factor identified in multiple sclerosis brain by HOFMAN, F. M, HINTON, D. R, JOHNSON, K, MERRILL, J. E

“…Frozen brain specimens from patients with multiple sclerosis (MS) and other neurologic diseases were analyzed using immunocytochemical techniques for the…”
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Human immunodeficiency virus 1 envelope proteins induce interleukin 1, tumor necrosis factor alpha, and nitric oxide in glial cultures derived from fetal, neonatal, and adult human brain by Koka, P, He, K, Zack, J A, Kitchen, S, Peacock, W, Fried, I, Tran, T, Yashar, S S, Merrill, J E

“…Although microglia are the only cells found to be productively infected in the central nervous system of acquired immunodeficiency disease syndrome (AIDS)…”
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