Search Results - "Merrill, Bryan D."

Gut-microbiota-targeted diets modulate human immune status by Wastyk, Hannah C., Fragiadakis, Gabriela K., Perelman, Dalia, Dahan, Dylan, Merrill, Bryan D., Yu, Feiqiao B., Topf, Madeline, Gonzalez, Carlos G., Van Treuren, William, Han, Shuo, Robinson, Jennifer L., Elias, Joshua E., Sonnenburg, Erica D., Gardner, Christopher D., Sonnenburg, Justin L.

“…Diet modulates the gut microbiome, which in turn can impact the immune system. Here, we determined how two microbiota-targeted dietary interventions,…”
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A metabolomics pipeline for the mechanistic interrogation of the gut microbiome by Han, Shuo, Van Treuren, Will, Fischer, Curt R., Merrill, Bryan D., DeFelice, Brian C., Sanchez, Juan M., Higginbottom, Steven K., Guthrie, Leah, Fall, Lalla A., Dodd, Dylan, Fischbach, Michael A., Sonnenburg, Justin L.

“…Gut microorganisms modulate host phenotypes and are associated with numerous health effects in humans, ranging from host responses to cancer immunotherapy to…”
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Robust variation in infant gut microbiome assembly across a spectrum of lifestyles by Olm, Matthew R, Dahan, Dylan, Carter, Matthew M, Merrill, Bryan D, Yu, Feiqiao B, Jain, Sunit, Meng, Xiandong, Tripathi, Surya, Wastyk, Hannah, Neff, Norma, Holmes, Susan, Sonnenburg, Erica D, Jha, Aashish R, Sonnenburg, Justin L

“…Infant microbiome assembly has been intensely studied in infants from industrialized nations, but little is known about this process in nonindustrialized…”
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Bacteroides thetaiotaomicron-Infecting Bacteriophage Isolates Inform Sequence-Based Host Range Predictions by Hryckowian, Andrew J., Merrill, Bryan D., Porter, Nathan T., Van Treuren, William, Nelson, Eric J., Garlena, Rebecca A., Russell, Daniel A., Martens, Eric C., Sonnenburg, Justin L.

“…Our emerging view of the gut microbiome largely focuses on bacteria, while less is known about other microbial components, such as bacteriophages (phages)…”
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DDX6 Represses Aberrant Activation of Interferon-Stimulated Genes by Lumb, Jennifer H., Li, Qin, Popov, Lauren M., Ding, Siyuan, Keith, Marie T., Merrill, Bryan D., Greenberg, Harry B., Li, Jin Billy, Carette, Jan E.

“…The innate immune system tightly regulates activation of interferon-stimulated genes (ISGs) to avoid inappropriate expression. Pathological ISG activation…”
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The CIAMIB: a Large and Metabolically Diverse Collection of Inflammation-Associated Bacteria from the Murine Gut by Wong, Erin Oi-Yan, Brownlie, Emma Joan Elizabeth, Ng, Katharine Michelle, Kathirgamanathan, Sornnujah, Yu, Feiqiao Brian, Merrill, Bryan D, Huang, Kerwyn Casey, Martin, Alberto, Tropini, Carolina, Navarre, William Wiley

“…Gut inflammation directly impacts the growth and stability of commensal gut microbes and can lead to long-lasting changes in microbiota composition that can…”
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Characterization of Five Novel Brevibacillus Bacteriophages and Genomic Comparison of Brevibacillus Phages by Berg, Jordan A, Merrill, Bryan D, Crockett, Justin T, Esplin, Kyle P, Evans, Marlee R, Heaton, Karli E, Hilton, Jared A, Hyde, Jonathan R, McBride, Morgan S, Schouten, Jordan T, Simister, Austin R, Thurgood, Trever L, Ward, Andrew T, Breakwell, Donald P, Hope, Sandra, Grose, Julianne H

“…Brevibacillus laterosporus is a spore-forming bacterium that causes a secondary infection in beehives following European Foulbrood disease. To better…”
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A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites by Dodd, Dylan, Spitzer, Matthew H., Van Treuren, William, Merrill, Bryan D., Hryckowian, Andrew J., Higginbottom, Steven K., Le, Anthony, Cowan, Tina M., Nolan, Garry P., Fischbach, Michael A., Sonnenburg, Justin L.

“…A pathway for the production of aromatic amino acid metabolites in Clostridium sporogenes is described; modulation of serum levels of these metabolites in…”
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Software-based analysis of bacteriophage genomes, physical ends, and packaging strategies by Merrill, Bryan D, Ward, Andy T, Grose, Julianne H, Hope, Sandra

“…Phage genome analysis is a rapidly growing field. Recurrent obstacles include software access and usability, as well as genome sequences that vary in sequence…”
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Bystander Phage Therapy: Inducing Host-Associated Bacteria to Produce Antimicrobial Toxins against the Pathogen Using Phages by Brady, T Scott, Fajardo, Christopher P, Merrill, Bryan D, Hilton, Jared A, Graves, Kiel A, Eggett, Dennis L, Hope, Sandra

“…is often present in beehives, including presence in hives infected with the causative agent of American Foulbrood (AFB), . In this work, 12 bacteriophages…”
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Ultra-deep sequencing of Hadza hunter-gatherers recovers vanishing gut microbes by Carter, Matthew M., Olm, Matthew R., Merrill, Bryan D., Dahan, Dylan, Tripathi, Surya, Spencer, Sean P., Yu, Feiqiao B., Jain, Sunit, Neff, Norma, Jha, Aashish R., Sonnenburg, Erica D., Sonnenburg, Justin L.

“…The gut microbiome modulates immune and metabolic health. Human microbiome data are biased toward industrialized populations, limiting our understanding of…”
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Community-led, integrated, reproducible multi-omics with anvi’o by Eren, A. Murat, Kiefl, Evan, Shaiber, Alon, Veseli, Iva, Miller, Samuel E., Schechter, Matthew S., Fink, Isaac, Pan, Jessica N., Yousef, Mahmoud, Fogarty, Emily C., Trigodet, Florian, Watson, Andrea R., Esen, Özcan C., Moore, Ryan M., Clayssen, Quentin, Lee, Michael D., Kivenson, Veronika, Graham, Elaina D., Merrill, Bryan D., Karkman, Antti, Blankenberg, Daniel, Eppley, John M., Sjödin, Andreas, Scott, Jarrod J., Vázquez-Campos, Xabier, McKay, Luke J., McDaniel, Elizabeth A., Stevens, Sarah L. R., Anderson, Rika E., Fuessel, Jessika, Fernandez-Guerra, Antonio, Maignien, Lois, Delmont, Tom O., Willis, Amy D.

“…Big data abound in microbiology, but the workflows designed to enable researchers to interpret data can constrain the biological questions that can be asked…”
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Independent host- and bacterium-based determinants protect a model symbiosis from phage predation by Lynch, Jonathan B., Bennett, Brittany D., Merrill, Bryan D., Ruby, Edward G., Hryckowian, Andrew J.

“…Bacteriophages (phages) are diverse and abundant constituents of microbial communities worldwide, capable of modulating bacterial populations in diverse ways…”
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A PCR-Based Method for Distinguishing between Two Common Beehive Bacteria, Paenibacillus larvae and Brevibacillus laterosporus by Berg, Jordan A, Merrill, Bryan D, Breakwell, Donald P, Hope, Sandra, Grose, Julianne H

“…and are two bacteria that are members of the family. Both are commonly found in beehives and have historically been difficult to distinguish from each other…”
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Phase-variable capsular polysaccharides and lipoproteins modify bacteriophage susceptibility in Bacteroides thetaiotaomicron by Porter, Nathan T., Hryckowian, Andrew J., Merrill, Bryan D., Fuentes, Jaime J., Gardner, Jackson O., Glowacki, Robert W. P., Singh, Shaleni, Crawford, Ryan D., Snitkin, Evan S., Sonnenburg, Justin L., Martens, Eric C.

“…A variety of cell surface structures dictate interactions between bacteria and their environment, including their viruses (bacteriophages). Members of the…”
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Bacteriophages as an alternative to conventional antibiotic use for the prevention or treatment of Paenibacillus larvae in honeybee hives by Brady, T. Scott, Merrill, Bryan D., Hilton, Jared A., Payne, Ashley M., Stephenson, Michael B., Hope, Sandra

“…[Display omitted] •39 phages tested for lysis in 59 P. larvae field isolates.•Phage treatment does not affect standard bee death rates.•Antibiotics reduce…”
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Characterization of Paenibacillus larvae bacteriophages and their genomic relationships to firmicute bacteriophages by Merrill, Bryan D, Grose, Julianne H, Breakwell, Donald P, Burnett, Sandra H

“…Paenibacillus larvae is a Firmicute bacterium that causes American Foulbrood, a lethal disease in honeybees and is a major source of global agricultural…”
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The genomes, proteomes, and structures of three novel phages that infect the Bacillus cereus group and carry putative virulence factors by Grose, Julianne H, Belnap, David M, Jensen, Jordan D, Mathis, Andrew D, Prince, John T, Merrill, Bryan D, Burnett, Sandra H, Breakwell, Donald P

“…This article reports the results of studying three novel bacteriophages, JL, Shanette, and Basilisk, which infect the pathogen Bacillus cereus and carry genes…”
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Putative type 1 thymidylate synthase and dihydrofolate reductase as signature genes of a novel Bastille-like group of phages in the subfamily Spounavirinae by Asare, Paul Tetteh, Jeong, Tae-Yong, Ryu, Sangryeol, Klumpp, Jochen, Loessner, Martin J, Merrill, Bryan D, Kim, Kwang-Pyo

“…Spounavirinae viruses have received an increasing interest as tools for the control of harmful bacteria due to their relatively broad host range and strictly…”
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Complete Genome Sequences of Paenibacillus larvae Phages BN12, Dragolir, Kiel007, Leyra, Likha, Pagassa, PBL1c, and Tadhana by Walker, Jamison K, Merrill, Bryan D, Berg, Jordan A, Dhalai, Aziza, Dingman, Douglas W, Fajardo, Chris P, Graves, Kiel, Hill, Hunter L, Hilton, Jared A, Imahara, Cameron, Knabe, Bradley K, Mangohig, James, Monk, Josh, Mun, Heejin, Payne, Ashley M, Salisbury, Alicia, Stamereilers, Casey, Velez, Kathie, Ward, Andy T, Breakwell, Donald P, Grose, Julianne H, Hope, Sandra, Tsourkas, Philippos K

“…We present here the complete genomes of eight phages that infect , the causative agent of American foulbrood in honeybees. Phage PBL1c was originally isolated…”
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