Search Results - "Merola, Roberta"
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Circulating cell free DNA and citrullinated histone H3 as useful biomarkers of NETosis in endometrial cancer
Published in Journal of experimental & clinical cancer research (21-04-2022)“…Cancer mortality is mainly caused by organ failure and thrombotic events. It has been demonstrated that NETosis, a chromatin release mechanism implemented by…”
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Iodixanol versus iopromide in cancer patients: Evidence from a randomized clinical trial
Published in Journal of cellular physiology (01-03-2018)“…To assess the safety profile of iso‐osmolar contrast medium (CM) versus low osmolar CM in cancer patients with an estimated glomerular filtration rate (eGFR)…”
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Long-Term Response in a Patient with del(5q) Myelodysplastic Syndrome Who Discontinued Lenalidomide and Obtained a Good Response and Tolerance to Rechallenge
Published in Case reports in oncology (25-04-2014)“…Background: The introduction of the immunomodulatory drug lenalidomide has revolutionized the treatment of patients with myelodysplastic syndromes (MDS) and…”
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Epidermal growth factor receptor gene copy number may predict lapatinib sensitivity in HER2-positive metastatic breast cancer
Published in Expert opinion on pharmacotherapy (01-04-2013)“…Lapatinib, a dual HER2/EGFR tyrosine kinase inhibitor (TKI), associated to capecitabine represents the treatment of choice in HER2-positive metastatic breast…”
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Epithelial-Restricted Gene Profile of Primary Cultures from Human Prostate Tumors: A Molecular Approach to Predict Clinical Behavior of Prostate Cancer
Published in Molecular cancer research (01-02-2006)“…The histopathologic and molecular heterogeneity of prostate cancer and the limited availability of human tumor tissue make unraveling the mechanisms of…”
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Regaining the response to erythropoietin following azacitidine in chronic myelomonocytic leukemia previously evolved from refractory anemia
Published in Blood research (01-09-2015)“…KCI Citation Count: 0…”
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Epidermal growth factor receptor gene copy number in 101 advanced colorectal cancer patients treated with chemotherapy plus cetuximab
Published in Journal of translational medicine (16-04-2010)“…Responsiveness to Cetuximab alone can be mediated by an increase of Epidermal Growth factor Receptor (EGFR) Gene Copy Number (GCN). Aim of this study was to…”
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Long-term hematological response in a patient with 5q- syndrome after suspension of lenalidomide therapy and further improvement with deferasirox therapy
Published in Blood research (01-06-2014)“…KCI Citation Count: 0…”
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Genetic profile identification in clinically localized prostate carcinoma
Published in Urologic oncology (01-09-2009)“…Abstract Purpose To confirm our previously obtained results, we genetically characterized prostate cancer from patients undergo radical prostatectomy in a…”
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Comprehensive Characterization of Cancer Driver Genes and Mutations
Published in Cell (05-04-2018)“…Identifying molecular cancer drivers is critical for precision oncology. Multiple advanced algorithms to identify drivers now exist, but systematic attempts to…”
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Pathogenic Germline Variants in 10,389 Adult Cancers
Published in Cell (05-04-2018)“…We conducted the largest investigation of predisposition variants in cancer to date, discovering 853 pathogenic or likely pathogenic variants in 8% of 10,389…”
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Circulating cell-free DNA content as blood based biomarker in endometrial cancer
Published in Oncotarget (29-12-2017)“…Altered circulating cell-free DNA (cfDNA) levels are related to cancer development and aggressiveness. Up to now, very few studies have been performed for…”
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Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas
Published in Cell reports (Cambridge) (03-04-2018)“…This integrated, multiplatform PanCancer Atlas study co-mapped and identified distinguishing molecular features of squamous cell carcinomas (SCCs) from five…”
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PCA3 in prostate cancer and tumor aggressiveness detection on 407 high-risk patients: a National Cancer Institute experience
Published in Journal of experimental & clinical cancer research (06-02-2015)“…Prostate cancer (PCa) is the most common male cancer in Europe and the US. The early diagnosis relies on prostate specific antigen (PSA) serum test, even if it…”
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Abstract 350: Che-1/aatf-induced transcriptionally active chromatin promotes cell growth in multiple myeloma
Published in Cancer research (Chicago, Ill.) (01-07-2018)“…Abstract Tumor transformation is the result of genetic and epigenetic modifications that alter gene transcription, consequently producing a specific oncogenic…”
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Temozolomide Low-dose Chemotherapy in Newly Diagnosed Low-grade Gliomas: Activity, Safety, and Long-term Follow-up
Published in Tumori (01-05-2017)“…Purpose To explore the efficacy and toxicity of an extended schedule of temozolomide (50 mg/mq 1 week on/1 week off) in a population of newly diagnosed…”
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EGFR molecular profiling in advanced NSCLC: a prospective phase II study in molecularly/clinically selected patients pretreated with chemotherapy
Published in Journal of thoracic oncology (01-04-2012)“…The optimal use of epidermal growth factor receptor (EGFR)-related molecular markers to prospectively identify tyrosine kinase inhibitor (TKI)-sensitive…”
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