Search Results - "Merlini, P A"

Prothrombotic Genetic Risk Factors in Young Survivors of Myocardial Infarction by Ardissino, D., Mannucci, P.M., Merlini, P.A., Duca, F., Fetiveau, R., Tagliabue, L., Tubaro, M., Galvani, M., Ottani, F., Ferrario, M., Corral, J., Margaglione, M.

“…It has long been thought that an individual thrombotic tendency increases the risk of myocardial infarction, especially in young adults. Several…”
Get full text

Persistent activation of coagulation mechanism in unstable angina and myocardial infarction by MERLINI, P. A, BAUER, K. A, OLTRONA, L, ARDISSINO, D, CATTANEO, M, BELLI, C, MANNUCI, P. M, ROSENBERG, R. D

“…The blood coagulation system is activated in the acute phase of unstable angina and acute myocardial infarction. However, it remains unclear whether augmented…”
Get full text

Tissue-factor antigen and activity in human coronary atherosclerotic plaques by Ardissino, D, Merlini, P A, Ariëns, R, Coppola, R, Bramucci, E, Mannucci, P M

“…Coronary atherosclerotic-plaque thrombosis is a key event in the pathogenesis of unstable angina and myocardial infarction. Although plaque rupture or…”
Get more information

The association of factor V Leiden with myocardial infarction is replicated in 1880 patients with premature disease by MANNUCCI, P. M., ASSELTA, R., DUGA, S., GUELLA, I., SPREAFICO, M., LOTTA, L., MERLINI, P. A., PEYVANDI, F., KATHIRESAN, S., ARDISSINO, D.

“…See also Tosetto A. Thrombophilic mutations and cardiovascular disease: the case is still open. This issue, pp 2113–5. Summary.  Aims: Gain‐of‐function…”
Get full text

A novel polymorphism in intron 1a of the human factor VII gene (G73A): study of a healthy Italian population and of 190 young survivors of myocardial infarction by PEYVANDI, F, MANNUCCI, P. M, BUCCIARELLI, P, ZEINALI, S, AKHAVAN, S, SACCHI, E, MERLINI, P. A, PERRY, D. J

“…We have identified a novel polymorphism located in intron 1a of the human factor VII gene, caused by the nucleotide change G to A at position + 73. In a…”
Get full text

Direct thrombin inhibitors for the treatment of acute coronary syndromes and during percutaneous coronary interventions by Paoli, G, Merlini, P A, Ardissino, D

“…As acute coronary syndromes are principally sustained by plaque complication and subsequent thrombus formation, anticoagulant therapy plays a central role in…”
Get more information

Combination therapy with metoprolol and nifedipine versus monotherapy in patients with stable angina pectoris results of the international multicenter angina exercise (IMAGE) study by Savonitto, Stefano, Ardissino, Diego, Egstrup, Kenneth, Rasmussen, Klaus, Bae, Erling A., Omland, Tor, Schjelderup-mathiesen, Per M., Marraccini, Paolo, Wahlqvist, Inger, Merlini, Piera Angelica, Rehnqvist, Nina

“…Objectives. This study was designed to investigate whether combination therapy with metoprolol and nifedipine provides a greater anti-ischemic effect than does…”
Get full text

Thrombin activity and early outcome in unstable angina pectoris by ARDISSINO, D, MERLINI, P. A, GAMBA, G, BARBERIS, P, DEMICHELI, G, TESTA, S, COLOMBI, E, POLI, A, FETIVEAU, R, MONTEMARTINI, C

“…The blood coagulation system is frequently activated in the acute phase of unstable angina, but it is unknown whether the augmented function of the hemostatic…”
Get full text

C-reactive protein elevation and early outcome in patients with unstable angina pectoris by Oltrona, Luigi, Ardissino, Diego, Merlini, Piera A., Spinola, Alessandra, Chiodo, Federico, Pezzano, Antonio

“…C-reactive protein, a reactant of the acute phase of inflammation, has been shown to be increased in patients with unstable angina. Moreover, it has recently…”
Get full text

Phenotype commitment in vascular smooth muscle cells derived from coronary atherosclerotic plaques: differential gene expression of endothelial nitric oxide synthase by Rossi, M L, Marziliano, N, Merlini, P A, Bramucci, E, Canosi, U, Presbitero, P, Arbustini, E, Mannucci, P M, Ardissino, D

“…Unstable angina and myocardial infarction are the clinical manifestations of the abrupt thrombotic occlusion of an epicardial coronary artery as a result of…”
Get full text

Adjunctive stent implantation following directional coronary atherectomy in patients with coronary artery disease by Bramucci, Ezio, Angoli, Luigi, Merlini, Piera Angelica, Barberis, Paolo, Laudisa, Maria Luisa, Colombi, Elisabetta, Poli, Arnaldo, Kubica, Jaceck, Ardissino, Diego

“…Objectives. This prospective case-control study evaluated the acute and long-term results of stent implantation preceded by debulking of the plaque by means of…”
Get full text

Active platelet‐binding conformation of plasma von Willebrand factor in young women with acute myocardial infarction by PEYVANDI, F., HOLLESTELLE, M. J., PALLA, R., MERLINI, P. A., FEYS, H. B., VANHOORELBEKE, K., LENTING, P. J., MANNUCCI, P. M.

Get full text

Activation of the hemostatic mechanism after pharmacological cardioversion of acute nonvalvular atrial fibrillation by OLTRONA, L, BROCCOLINO, M, MERLINI, P. A, SPINOLA, A, PEZZANO, A, MANNUCCI, P. M

“…Given that the restoration of sinus rhythm after chronic atrial fibrillation is associated with embolic events, anticoagulation is prescribed before and after…”
Get full text

Twenty-four months clinical outcomes of sirolimus-eluting stents for the treatment of small coronary arteries: the long-term SES-SMART clinical study by Menozzi, Alberto, Solinas, Emilia, Ortolani, Paolo, Repetto, Alessandra, Saia, Francesco, Piovaccari, Giancarlo, Manari, Antonio, Magagnini, Enrico, Vignali, Luigi, Bonizzoni, Erminio, Merlini, Piera Angelica, Cavallini, Claudio, Ardissino, Diego

“…Aims It has been demonstrated that, in comparison with bare-metal stents (BMS), sirolimus-eluting stents (SES) reduce restenosis after the percutaneus…”
Get full text

Thrombin generation and activity during thrombolysis and concomitant heparin therapy in patients with acute myocardial infarction by Merlini, Piera Angelica, Bauer, Kenneth A, Oltrona, Luigi, Ardissino, Diego, Spinola, Alessandra, Cattaneo, Marco, Broccolino, Marco, Mannucci, Pier Mannuccio, Rosenberg, Robert D

“…Objectives. This prospective study investigated the behavior of thrombin generation and activity during thrombolysis and concomitant heparin administration…”
Get full text

Genetic polymorphisms to evaluate the risk of myocardial infarction: a long way away by Merlini, P A, Ardissino, D

Get more information

Effect of Transdermal Nitroglycerin or N-Acetylcysteine, or Both, in the Long-Term Treatment of Unstable Angina Pectoris by Ardissino, Diego, Merlini, Piera Angelica, Savonitto, Stefano, Demicheli, Gloria, Zanini, Paola, Bertocchi, Federico, Falcone, Colomba, Ghio, Stefano, Marinoni, Giampiero, Montemartini, Carlo, Mussini, Antonio

“…Objectives. This study was designed to evaluate whether the addition of transdermal nitroglycerin or oral N-acetylcysteine, or both, to conventional medical…”
Get full text

Coagulation markers and outcomes in acute coronary syndromes by Ardissino, Diego, Merlini, Piera Angelica, Eisenberg, Paul R., Kottke-Marchant, Kandice, Crenshaw, Brian S., Granger, Christopher B.

“…Am Heart J 1998;136:S7-S18…”
Get full text

Invasive coronary revascularisation is better than conservative treatment in patients with acute coronary syndromes by GONZI, GIANLUCA, MERLINI, PIERA ANGELICA, ARDISSINO, DIEGO

“…Cumulative all cause mortality was not significantly different between the two groups during long term follow up (death and non-fatal acute myocardial…”
Get full text

Persistent Thrombin Generation During Heparin Therapy in Patients With Acute Coronary Syndromes by Merlini, Piera Angelica, Ardissino, Diego, Bauer, Kenneth A, Oltrona, Luigi, Pezzano, Antonio, Bottasso, Biancamaria, Rosenberg, Robert D, Mannucci, Pier Mannuccio

“…Intravenous heparin, a fundamental therapy in the treatment of patients with acute coronary syndromes, acts by inhibiting thrombin and activated factors X, IX,…”
Get full text