Search Results - "Merkord, J"
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Influence of daily oral prophylactic selenium treatment on the dibutyltin dichloride (DBTC)-induced pancreatitis in rats
Published in EXCLI journal (01-01-2017)“…Dibutyltin dichloride (DBTC) is an organotin compound used as model for acute and chronic pancreatitis. Oxidative stress is one of the mechanisms of…”
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Pancreatic fibrosis in experimental pancreatitis induced by dibutyltin dichloride
Published in Gastroenterology (New York, N.Y. 1943) (01-05-1997)“…BACKGROUND & AIMS: Regulatory mechanisms in chronic pancreatitis finally resulting in pancreatic fibrosis cannot be studied sufficiently in human pancreas…”
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Acute interstitial pancreatitis in rats induced by dibutyltin dichloride (DBTC) : Pathogenesis and natural course of lesions
Published in Pancreas (01-11-1997)“…Dibutyltin dichloride (DBTC; 6 mg/kg body weight, i.v.) induced acute interstitial pancreatitis in rats. The course of the pancreatitis was examined within 28…”
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The Course of Pancreatic Fibrosis Induced by Dibutyltin Dichloride (DBTC)
Published in Annals of the New York Academy of Sciences (01-06-1999)“…In summary, in addition to an acute interstitial pancreatitis the organotin compound DBTC induced a pancreatic fibrosis in rats. The course of the pancreatic…”
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Influence of selenium treatment on the acute toxicity of dibutyltin dichloride in rats
Published in Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] (01-10-2006)“…Background/Aims: Dibutyltin dichloride (DBTC) is an organotin compound used as a model for acute pancreatitis. The aim was to determine the effect of various…”
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Cytokine mRNA levels and lymphocyte infiltration in pancreatic tissue during experimental chronic pancreatitis induced by dibutyltin dichloride
Published in Digestive diseases and sciences (01-08-2001)“…There is little information available regarding the role of inflammatory cells in the pathogenesis of chronic pancreatitis. Therefore, we analyzed the local…”
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Repeated administration of a mild acute toxic dose of di-n-butyltin dichloride at intervals of 3 weeks induces severe lesions in pancreas and liver of rats
Published in Human & experimental toxicology (01-08-2001)“…Di-n-butyltin dichloride (DBTC) induced thymus atrophy, bile duct lesions, pancreatitis, and liver lesions in rats. Depending on dose [6 and 8 mg/kg…”
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Heat shock response is associated with protection against acute interstitial pancreatitis in rats
Published in Digestive diseases and sciences (01-11-2000)“…We recently reported that hyperthermia induces pancreatic expression of heat shock proteins (HSPs), particularly HSP70 isoforms, and protects against cerulein…”
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Antidotal effects of 2,3-dimercaptopropane-1-sulfonic acid (DMPS) and meso-2,3-dimercaptosuccinic acid (DMSA) on the organotoxicity of dibutyltin dichloride (DBTC) in rats
Published in Human & experimental toxicology (01-02-2000)“…1. Dialkyltin compounds have been widely used in industry and agriculture, mainly as biocides, catalysts and plast stabilizer. In dependence on the length of…”
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Oxygen radical generation and acute pancreatitis : effects of dibutyltin dichloride/ethanol and ethanol on rat pancreas
Published in Pancreas (01-11-1995)“…Recent studies suggest that enhanced release of free oxygen radicals plays an important role in the pathogenesis of acute pancreatitis. Therefore, we studied…”
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Influence of daily oral prophylactic Selenium treatment on the DBTC-induced pancreatitis in rats
Published in Toxicology letters (05-10-2008)Get full text
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Acute pancreatitis and bile duct lesions in rat induced by dibutyltin dichloride
Published in Experimental pathology (1981) (1989)“…After i.v. or i.p. administration of a single dose of dibutyltin dichloride (DBTC) the following changes were observed in pancreas and bile ducts of male rats:…”
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Expression of multidrug resistance proteins in rat and human chronic pancreatitis
Published in Pancreas (01-01-2004)“…The expression of the ABC-transporters MDR-1, MRP1, and MRP-2 was investigated in healthy pancreas and in chronic pancreatitis tissue samples in rats and…”
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Expression of cytokine mRNA in an experimental model of chronic pancreatitis
Published in Gastroenterology (New York, N.Y. 1943) (15-04-1998)Get full text
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Trlchothecene T-2 toxine (T-2) induces toxlc effects on the developing immune system in rats
Published in Toxicology letters (01-08-1995)Get full text
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Electron Microscopic Detection of Tin Accumulation in Biliopancreatic Concrements after Induction of Chronic Pancreatitis in Rats by Di- n -butyltin Dichloride
Published in Ultrastructural pathology (2002)“…The organotin compound di- n -butyltin dichloride (DBTC) is able to induce an acute and later a chronic pancreatitis in rats. In previous papers the authors…”
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