Search Results - "Merkle, Roberta K."

Role of glycosylation in hyperphosphorylation of tau in Alzheimer’s disease by Liu, Fei, Zaidi, Tanweer, Iqbal, Khalid, Grundke-Iqbal, Inge, Merkle, Roberta K., Gong, Cheng-Xin

“…In Alzheimer’s disease (AD) brain, microtubule-associated protein tau is abnormally modified by hyperphosphorylation and glycosylation, and is aggregated as…”
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Carbohydrate composition analysis of glycoconjugates by gas-liquid chromatography/mass spectrometry by Merkle, R K, Poppe, I

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Lectin affinity chromatography of glycopeptides by Merkle, R K, Cummings, R D

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Cloning, expression, purification, and characterization of the murine lysosomal acid α-mannosidase by Merkle, Roberta K, Zhang, Yong, Ruest, Paul J, Lal, Anita, Liao, Yung-Feng, Moremen, Kelley W

“…Catabolism of α-linked mannose residues on eukaryotic glycoproteins is accomplished by a broad specificity lysosomal α-mannosidase (EC 3.2.1.24). Based on…”
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The dysfunctional LDL receptor in a monensin-resistant mutant of Chinese hamster ovary cells lacks selected O-linked oligosaccharides by Seguchi, T, Merkle, R K, Ono, M, Kuwano, M, Cummings, R D

“…The Chinese hamster ovary (CHO) cell line Monr31, which is resistant to the cytotoxic ionophore monensin, produces a receptor for the low density lipoprotein…”
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Cloning, expression, purification, and characterization of the acid α-mannosidase from Trypanosoma cruzi by Vandersall-Nairn, Alison S., Merkle, Roberta K., O'Brien, Keith, Oeltmann, Thomas N., Moremen, Kelley W.

“…The acid α-mannosidase of Trypanosoma cruzi is a broad-specificity hydrolase involved in the catabolism of glycoconjugates, presumably in the digestive…”
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Isolation and characterization of a class II alpha-mannosidase cDNA from lepidopteran insect cells by Jarvis, D.L, Bohlmeyer, D.A, Liao, Y.F, Lomax, K.K, Merkle, R.K, Weinkauf, C, Moremen, K.W

“…Lepidopteran insect cells are used routinely as hosts for foreign glycoprotein expression by recombinant baculoviruses, but the precise nature of their…”
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Cloning, expression, purification, and characterization of the murine lysosomal acid α-mannosidase1The sequences reported in this paper have been deposited in the GenBank data base with accession number U87240.1 by Merkle, Roberta K, Zhang, Yong, Ruest, Paul J, Lal, Anita, Liao, Yung-Feng, Moremen, Kelley W

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Complex-type N-linked oligosaccharides of gp120 from human immunodeficiency virus type 1 contain sulfated N-acetylglucosamine by SHILATIFARD, A, MERKLE, R. K, HELLAND, D. E, WELLES, J. L, HASELTINE, W. A, CUMMINGS, R. D

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Immunocytochemical Localization of Mutant Low Density Lipoprotein Receptors That Fail to Reach the Golgi Complex by Pathak, Ravindra K., Merkle, Roberta K., Cummings, Richard D., Goldstein, Joseph L., Brown, Michael S., Richard G. W. Anderson

“…In the low density lipoprotein (LDL) receptor system, blocks in intracellular movement of a cell surface receptor result from naturally occurring mutations…”
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gp160 of HIV-I synthesized by persistently infected Molt-3 cells is terminally glycosylated: evidence that cleavage of gp160 occurs subsequent to oligosaccharide processing by Merkle, R K, Helland, D E, Welles, J L, Shilatifard, A, Haseltine, W A, Cummings, R D

“…The envelope glycoprotein of HIV-I in infected, cultured human T cells is synthesized as a precursor of apparent Mr 160 kDa (gp160) and is cleaved to two…”
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Characterization of an S-type lectin purified from porcine heart by Merkle, R K, Zhou, Q, Schultz, T K, Harper, W B, Cummings, R D

“…We have purified a carbohydrate-binding protein from porcine heart by affinity chromatography on asialofetuin-Sepharose and have characterized this protein…”
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Enzymatic sulfation of N-glycosidically linked oligosaccharides by endothelial cell membranes by Merkle, R K, Heifetz, A

“…Homogenates of human vascular endothelial cells catalyze the transfer of 35SO4 from 3'-phosphoadenosine 5'-phospho[35S]sulfate into macromolecular endogenous…”
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Localization of adenylate cyclase during development of Dictyostelium discoideum by Merkle, R K, Rutherford, C L

“…Cyclic AMP is known to function as the chemotactic signal during aggregation of single-celled amoebae of the cellular slime mold Dictyostelium discoideum…”
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Localization and levels of cyclic AMP during development of Dictyostelium discoideum by Merkle, R K, Cooper, K K, Rutherford, C L

“…Cyclic AMP functions as the chemotactic signal during aggregation of amoebae of the cellular slime mold Dictyostelium discoideum. Evidence suggests that cAMP…”
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