Search Results - "Merker, J D"

ESMO recommendations on the use of circulating tumour DNA assays for patients with cancer: a report from the ESMO Precision Medicine Working Group by Pascual, J., Attard, G., Bidard, F.-C., Curigliano, G., De Mattos-Arruda, L., Diehn, M., Italiano, A., Lindberg, J., Merker, J.D., Montagut, C., Normanno, N., Pantel, K., Pentheroudakis, G., Popat, S., Reis-Filho, J.S., Tie, J., Seoane, J., Tarazona, N., Yoshino, T., Turner, N.C.

“…Circulating tumour DNA (ctDNA) assays conducted on plasma are rapidly developing a strong evidence base for use in patients with cancer. The European Society…”
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Efficacy and safety of midostaurin in patients with advanced systemic mastocytosis: 10-year median follow-up of a phase II trial by DeAngelo, D J, George, T I, Linder, A, Langford, C, Perkins, C, Ma, J, Westervelt, P, Merker, J D, Berube, C, Coutre, S, Liedtke, M, Medeiros, B, Sternberg, D, Dutreix, C, Ruffie, P-A, Corless, C, Graubert, T J, Gotlib, J

“…Patients with advanced systemic mastocytosis (SM) (e.g. aggressive SM (ASM), SM with an associated hematologic neoplasm (SM-AHN) and mast cell leukemia (MCL))…”
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STAT3 mutations are frequent in CD30+ T-cell lymphomas and T-cell large granular lymphocytic leukemia by Ohgami, R S, Ma, L, Merker, J D, Martinez, B, Zehnder, J L, Arber, D A

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Complete response to gemtuzumab ozogamicin in a patient with refractory mast cell leukemia by Alvarez-Twose, I, Martínez-Barranco, P, Gotlib, J, García-Montero, A, Morgado, J M, Jara-Acevedo, M, Merker, J D, Peñalver, F J, Matito, A, Hou, Y, Sánchez-Muñoz, L, Mayado, A, Mollejo, M, Escribano, L, Orfao, A

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Growth of Histoplasma capsulatum isolates is better on potato dextrose agar with chloramphenicol than on brain heart infusion agar by Burtelow, M.A., Merker, J.D., Baron, E.J.

“…Histoplasma capsulatum ( H.  capsulatum) grows poorly on standard, non-enriched laboratory culture media. In many clinical laboratories, brain heart infusion…”
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Patterns of Heteroduplex Formation Associated With the Initiation of Meiotic Recombination in the Yeast Saccharomyces cerevisiae by Merker, Jason D, Dominska, Margaret, Petes, Thomas D

“…The double-strand break repair (DSBR) model of recombination predicts that heteroduplexes will be formed in regions that flank the double-strand break (DSB)…”
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Context dependence of meiotic recombination hotspots in yeast: the relationship between recombination activity of a reporter construct and base composition by Petes, Thomas D, Merker, Jason D

“…Borde and colleagues reported that a reporter plasmid inserted at different genomic locations in Saccharomyces cerevisiae had different levels of meiotic…”
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A Genetic Approach for Identifying Critical Residues in the Fingers and Palm Subdomains of HIV-1 Reverse Transcriptase by Wrobel, John A., Chao, Shih-Fong, Conrad, Michael J., Merker, Jason D., Swanstrom, Ronald, Pielak, Gary J., Hutchison, Clyde A.

“…By using oligonucleotide-directed saturation mutagenesis, we collected 366 different single amino acid substitutions in a 109-aa segment (residues 95-203) in…”
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Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC) by Horak, Peter, Griffith, Malachi, Danos, Arpad M., Pitel, Beth A., Madhavan, Subha, Liu, Xuelu, Chow, Cynthia, Williams, Heather, Carmody, Leigh, Barrow-Laing, Lisa, Rieke, Damian, Kreutzfeldt, Simon, Stenzinger, Albrecht, Tamborero, David, Benary, Manuela, Rajagopal, Padma Sheila, Ida, Cristiane M., Lesmana, Harry, Satgunaseelan, Laveniya, Merker, Jason D., Tolstorukov, Michael Y., Campregher, Paulo Vidal, Warner, Jeremy L., Rao, Shruti, Natesan, Maya, Shen, Haolin, Venstrom, Jeffrey, Roy, Somak, Tao, Kayoko, Kanagal-Shamanna, Rashmi, Xu, Xinjie, Ritter, Deborah I., Pagel, Kym, Krysiak, Kilannin, Dubuc, Adrian, Akkari, Yassmine M., Li, Xuan Shirley, Lee, Jennifer, King, Ian, Raca, Gordana, Wagner, Alex H., Li, Marylin M., Plon, Sharon E., Kulkarni, Shashikant, Griffith, Obi L., Chakravarty, Debyani, Sonkin, Dmitriy

“…Several professional societies have published guidelines for the clinical interpretation of somatic variants, which specifically address diagnostic,…”
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yeast HSM3 gene is not involved in DNA mismatch repair in rapidly dividing cells by Merker, J.D, Datta, A, Kolodner, R.D, Petes, T.D

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Microarray Detection of Human Parainfluenzavirus 4 Infection Associated with Respiratory Failure in an Immunocompetent Adult by Chiu, Charles Y., Rouskin, Silvi, Koshy, Anita, Urisman, Anatoly, Fischer, Kael, Yagi, Shigeo, Schnurr, David, Eckburg, Paul B., Tompkins, Lucy S., Blackburn, Brian G., Merker, Jason D., Patterson, Bruce K., Ganem, Don, DeRisi, Joseph L.

“…A pan-viral DNA microarray, the Virochip (University of California, San Francisco), was used to detect human parainfluenzavirus 4 (HPIV-4) infection in an…”
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Comprehensive whole-genome sequencing of an early-stage primary myelofibrosis patient defines low mutational burden and non-recurrent candidate genes by Merker, Jason D, Roskin, Krishna M, Ng, Dana, Pan, Cuiping, Fisk, Dianna G, King, Jasmine J, Hoh, Ramona, Stadler, Michael, Okumoto, Lawrence M, Abidi, Parveen, Hewitt, Rhonda, Jones, Carol D, Gojenola, Linda, Clark, Michael J, Zhang, Bing, Cherry, Athena M, George, Tracy I, Snyder, Michael, Boyd, Scott D, Zehnder, James L, Fire, Andrew Z, Gotlib, Jason

“…In order to identify novel somatic mutations associated with classic BCR/ABL1-negative myeloproliferative neoplasms, we performed high-coverage genome…”
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The histone methylase Set2p and the histone deacetylase Rpd3p repress meiotic recombination at the HIS4 meiotic recombination hotspot in Saccharomyces cerevisiae by Merker, Jason D., Dominska, Margaret, Greenwell, Patricia W., Rinella, Erica, Bouck, David C., Shibata, Yoichiro, Strahl, Brian D., Mieczkowski, Piotr, Petes, Thomas D.

“…The rate of meiotic recombination in the yeast Saccharomyces cerevisiae varies widely in different regions of the genome with some genes having very high…”
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Complete response to gemtuzumab ozogamicin in a patient with refractory mast cell leukemia by Alvarez-Twose, I, Martínez-Barranco, P, Gotlib, J, García-Montero, A, Morgado, J M, Jara-Acevedo, M, Merker, J D, Peñalver, F J, Matito, A, Hou, Y, Sánchez-Muñoz, L, Mayado, A, Mollejo, M, Escribano, L, Orfao, A

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