Search Results - "Merkel, F"

Trafficking of adeno‐associated virus vectors across a model of the blood–brain barrier; a comparative study of transcytosis and transduction using primary human brain endothelial cells by Merkel, Steven F., Andrews, Allison M., Lutton, Evan M., Mu, Dakai, Hudry, Eloise, Hyman, Bradley T., Maguire, Casey A., Ramirez, Servio H.

“…Developing therapies for central nervous system (CNS) diseases is exceedingly difficult because of the blood–brain barrier (BBB). Notably, emerging…”
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Blood biomarkers for brain injury: What are we measuring? by Kawata, Keisuke, Liu, Charles Y., Merkel, Steven F., Ramirez, Servio H., Tierney, Ryan T., Langford, Dianne

“…•Diagnosis for mild TBI remains challenging, as prognosis and return-to-activity decisions are based largely on self-report.•Identifying a blood biomarker to…”
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Mechanical Injury Induces Brain Endothelial-Derived Microvesicle Release: Implications for Cerebral Vascular Injury during Traumatic Brain Injury by Andrews, Allison M, Lutton, Evan M, Merkel, Steven F, Razmpour, Roshanak, Ramirez, Servio H

“…It is well established that the endothelium responds to mechanical forces induced by changes in shear stress and strain. However, our understanding of vascular…”
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Exosome-associated AAV vector as a robust and convenient neuroscience tool by Hudry, E, Martin, C, Gandhi, S, György, B, Scheffer, D I, Mu, D, Merkel, S F, Mingozzi, F, Fitzpatrick, Z, Dimant, H, Masek, M, Ragan, T, Tan, S, Brisson, A R, Ramirez, S H, Hyman, B T, Maguire, C A

“…Adeno-associated virus (AAV) vectors are showing promise in gene therapy trials and have proven to be extremely efficient biological tools in basic…”
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Dexamethasone Attenuates the Enhanced Rewarding Effects of Cocaine Following Experimental Traumatic Brain Injury by Merkel, Steven F., Andrews, Allison M., Lutton, Evan M., Razmpour, Roshanak, Cannella, Lee Anne, Ramirez, Servio H.

“…Clinical studies have identified traumatic brain injury (TBI) as a risk factor for the development of cocaine dependence. This claim is supported by our recent…”
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Attenuation of HIV-1 replication in macrophages by cannabinoid receptor 2 agonists by Ramirez, Servio H., Reichenbach, Nancy L., Fan, Shongshan, Rom, Slava, Merkel, Steven F., Wang, Xu, Ho, Wen‐zhe, Persidsky, Yuri

“…CB2 expression is upregulated in HIV‐1 infected macrophages; CB2 agonists limits infection by inhibition of the HIV‐1‐LTR. Infiltrating monocytes and…”
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Widespread Vascularization and Correlation of Glycosaminoglycan Accumulation to Tendon Pain in Human Plantar Fascia Tendinopathy by Merkel, Max F.R., Svensson, Rene B., Jakobsen, Jens R., Mackey, Abigail L., Schjerling, Peter, Herzog, Robert B., Magnusson, S. Peter, Konradsen, Lars, Krogsgaard, Michael R., Kjær, Michael, Johannsen, Finn E.

“…Background: Plantar fasciitis is a painful tendinous condition (tendinopathy) with a high prevalence in athletes. While a healthy tendon has limited blood…”
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ORTHOSKIM: In silico sequence capture from genomic and transcriptomic libraries for phylogenomic and barcoding applications by Pouchon, Charles, Boyer, Frédéric, Roquet, Cristina, Denoeud, France, Chave, Jérome, Coissac, Eric, Alsos, Inger Greve, Lavergne, Sébastien, Smyčka, J, Boleda, M, Thuiller, W, Gielly, L, Taberlet, P, Rioux, D, Hombiat, A, Bzeznick, B, Alberti, A, Wincker, P, Orvain, C, Perrier, C, Douzet, R, Rome, M, Valay, JG, Aubert, S, Zimmermann, N, Wüest, RO, Latzin, S, Wipf, S, Van Es, J, Garraud, L, Villaret, JC, Abdulhak, S, Bonnet, V, Huc, S, Fort, N, Legland, T, Sanz, T, Pache, G, Mikolajczak, A, Noble, V, Michaud, H, Offerhaus, B, Pires, M, Morvant, Y, Dentant, C, Salomez, P, Bonet, R, Delahaye, T, Leccia, MF, Perfus, M, Eggenberg, S, Möhl, A, Hurdu, B, Pușcaș, M, Slovák, M, Alsos, IG, Merkel, F, Lammers, Y, Coissac, E, Pouchon, C, Alberti, A, Denoeud, F, Wincker, P

“…Low‐coverage whole genome shotgun sequencing (or genome skimming) has emerged as a cost‐effective method for acquiring genomic data in nonmodel organisms. This…”
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Adolescent Traumatic Brain Injury Induces Chronic Mesolimbic Neuroinflammation with Concurrent Enhancement in the Rewarding Effects of Cocaine in Mice during Adulthood by Merkel, Steven F, Razmpour, Roshanak, Lutton, Evan M, Tallarida, Christopher S, Heldt, Nathan A, Cannella, Lee Anne, Persidsky, Yuri, Rawls, Scott M, Ramirez, Servio H

“…Clinical psychiatric disorders of depression, anxiety, and substance abuse are most prevalent after traumatic brain injury (TBI). Pre-clinical research has…”
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Identification and dynamic regulation of tight junction protein expression in human neural stem cells by Watters, Andrea K, Rom, Slava, Hill, Jeremy D, Dematatis, Marie K, Zhou, Yu, Merkel, Steven F, Andrews, Allison M, Cena, Jonathan, Potula, Raghava, Skuba, Andrew, Son, Young-Jin, Persidsky, Yuri, Ramirez, Servio H

“…Recent reports indicate that neural stem cells (NSCs) exist in a cluster-like formation in close proximity to cerebral microvessels. Similar appearing clusters…”
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Gene Therapy for the Nervous System: Challenges and New Strategies by Maguire, Casey A., Ramirez, Servio H., Merkel, Steven F., Sena-Esteves, Miguel, Breakefield, Xandra O.

“…Current clinical treatments for central nervous system (CNS) diseases, such as Parkinson’s disease and glioblastoma do not halt disease progression and have…”
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Factors affecting increased risk for substance use disorders following traumatic brain injury: What we can learn from animal models by Merkel, Steven F., Cannella, Lee Anne, Razmpour, Roshanak, Lutton, Evan, Raghupathi, Ramesh, Rawls, Scott M., Ramirez, Servio H.

“…Effects of traumatic brain injury (TBI) on mechanisms implicated in substance use disorders (SUDs). Recent studies find that TBI may affect many key brain…”
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Erratum: Exosome-associated AAV vector as a robust and convenient neuroscience tool by Hudry, E, Martin, C, Gandhi, S, György, B, Scheffer, D I, Mu, D, Merkel, S F, Mingozzi, F, Fitzpatrick, Z, Dimant, H, Masek, M, Ragan, T, Tan, S, Brisson, A R, Ramirez, S H, Hyman, B T, Maguire, C A

“…Correction to: Gene Therapy (2016) 23, 380–392; doi:10.1038/gt.2016.11 The initial Figure 2a was erroneously generated from a file from a mouse injected with…”
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Five and 10 year follow-up of en bloc small pediatric kidneys in adult recipients by Merkel, F.K

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Managers’ research education, the use of FX derivatives and corporate speculation by Entrop, Oliver, Merkel, Matthias F.

“…In contrast to the U.S., many executive managers of firms in German-speaking countries have a PhD. In this paper we analyze if a research-oriented background…”
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Multiplexing PCR allows the identification of within‐species genetic diversity in ancient eDNA by Lammers, Y., Taberlet, P., Coissac, E., Elliott, L. D., Merkel, M. F., Pitelkova, I., Alsos, I. G.

“…Sedimentary ancient DNA (sedaDNA) has rarely been used to obtain population‐level data due to either a lack of taxonomic resolution for the molecular method…”
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Mechanical properties, collagen and glycosaminoglycan content of equine superficial digital flexor tendons are not affected by training by Yeung, Ching-Yan Chloé, Svensson, René B, Mogensen, Nikoline M B, Merkel, Max F R, Schjerling, Peter, Jokipii-Utzon, Anja, Zhang, Cheng, Carstensen, Helena, Buhl, Rikke, Kjaer, Michael

“…Physical activity can activate extracellular matrix (ECM) protein synthesis and influence the size and mechanical properties of tendon. In this study, we aimed…”
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Characterization of human fetal brain endothelial cells reveals barrier properties suitable for in vitro modeling of the BBB with syngenic co-cultures by Andrews, Allison M, Lutton, Evan M, Cannella, Lee A, Reichenbach, Nancy, Razmpour, Roshanak, Seasock, Matthew J, Kaspin, Steven J, Merkel, Steven F, Langford, Dianne, Persidsky, Yuri, Ramirez, Servio H

“…Endothelial cells (ECs) form the basis of the blood–brain barrier (BBB), a physical barrier that selectively restricts transport into the brain. In vitro…”
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Does Gender-Fair Language Pay Off? The Social Perception of Professions from a Cross-Linguistic Perspective by Horvath, Lisa K, Merkel, Elisa F, Maass, Anne, Sczesny, Sabine

“…In many languages, masculine forms (e.g., German Lehrer, "teachers, masc.") have traditionally been used to refer to both women and men, although feminine…”
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Transplantation of small en bloc kidneys including a horseshoe kidney from donors aged 2 to 60 months to adult recipients: a 13-year experience by Merkel, F.K

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