Search Results - "Merk, Hans F"

Omalizumab is Effective in Cold Urticaria - Results of a Randomized, Placebo Controlled Trial by Metz, Martin, M.D, Schütz, Andrea, M.D, Weller, Karsten, M.D, Gorczyza, Marina, M.D, Zimmer, Sebastian, M.D, Staubach, Petra, M.D, Merk, Hans F., M.D, Maurer, Marcus, M.D

“…Cold urticaria is a potentially life-threatening disease and placebo treatment of patients does not provide protection from cold-induced systemic reactions…”
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Prospective Randomized Long-Term Study on the Efficacy and Safety of UV-Free Blue Light for Treating Mild Psoriasis Vulgaris by Pfaff, Stephanie, Liebmann, Jörg, Born, Matthias, Merk, Hans F, von Felbert, Verena

“…Blue light irradiation reduces the proliferation of keratinocytes and modulates T-cell immune response in vitro and has been shown to reduce the severity of…”
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SNAP-Tag Technology Mediates Site Specific Conjugation of Antibody Fragments with a Photosensitizer and Improves Target Specific Phototoxicity in Tumor Cells by Hussain, Ahmad Fawzi, Kampmeier, Florian, von Felbert, Verena, Merk, Hans-F, Tur, Mehmet Kemal, Barth, Stefan

“…Cancer cells can be killed by photosensitizing agents that induce toxic effects when exposed to nonhazardous light, but this also causes significant damage to…”
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Species-Specific Differential AhR Expression Protects Human Neural Progenitor Cells against Developmental Neurotoxicity of PAHs by Gassmann, Kathrin, Abel, Josef, Bothe, Hanno, Haarmann-Stemmann, Thomas, Merk, Hans F., Quasthoff, Kim N., Rockel, Thomas Dino, Schreiber, Timm, Fritsche, Ellen

“…Background: Because of their lipophilicity, persistent organic pollutants (POPs) cross the human placenta, possibly affecting central nervous system…”
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Hyperpigmentation and higher incidence of cutaneous malignancies in moderate-high PCB- and dioxin exposed individuals by Leijs, Marike M., Esser, André, Amann, Philipp M., Schettgen, Thomas, Gube, Monika, Merk, Hans F., Kraus, Thomas, Baron, Jens M.

“…Polychlorinated biphenyls (PCB) are well known persistent and toxic environmental pollutants. Our aim was to identify effects of moderate-high exposure to…”
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Prospective, Randomized Study on the Efficacy and Safety of Local UV-Free Blue Light Treatment of Eczema by Keemss, Kim, Pfaff, Stephanie C, Born, Matthias, Liebmann, Jörg, Merk, Hans F, von Felbert, Verena

“…Blue light was shown to reduce the activation of T cells and modulate cytokine release in vitro. Therefore, we investigated the efficacy of blue light in the…”
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Polysorbate 80 in medical products and nonimmunologic anaphylactoid reactions by Coors, Esther A, Seybold, Heidi, Merk, Hans F, Mahler, Vera

“…Polyoxyethylene-sorbitan-20-monooleate (also known as polysorbate 80 and Tween 80) is a solubilizing agent ubiquitously used in nutritives, creams, ointments,…”
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Prospective randomized study on the efficacy of blue light in the treatment of psoriasis vulgaris by Weinstabl, Antonia, Hoff-Lesch, Susanne, Merk, Hans F, von Felbert, Verena

“…Blue light has no known toxic effects on human skin, but reduces the proliferative capacity of keratinocytes in vitro. We therefore investigated the efficacy…”
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Interferon Alpha Signalling and Its Relevance for the Upregulatory Effect of Transporter Proteins Associated with Antigen Processing (TAP) in Patients with Malignant Melanoma by Heise, Ruth, Amann, Philipp M, Ensslen, Silke, Marquardt, Yvonne, Czaja, Katharina, Joussen, Sylvia, Beer, Daniel, Abele, Rupert, Plewnia, Gabriele, Tampé, Robert, Merk, Hans F, Hermanns, Heike M, Baron, Jens M

“…Interferon alpha (IFNα) is routinely used in the clinical practice for adjuvant systemic melanoma therapy. Understanding the molecular mechanism of IFNα…”
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Characterization of SLCO5A1/OATP5A1, a solute carrier transport protein with non-classical function by Sebastian, Katrin, Detro-Dassen, Silvia, Rinis, Natalie, Fahrenkamp, Dirk, Müller-Newen, Gerhard, Merk, Hans F, Schmalzing, Günther, Zwadlo-Klarwasser, Gabriele, Baron, Jens Malte

“…Organic anion transporting polypeptides (OATP/SLCO) have been identified to mediate the uptake of a broad range of mainly amphipathic molecules. Human OATP5A1…”
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Management of patients with seasonal allergic rhinitis: Diagnostic consideration of sensitization to non‐frequent pollen allergens by Höflich, Conny, Balakirski, Galina, Hajdu, Zuzanna, Baron, Jens Malte, Fietkau, Katharina, Merk, Hans F., Strassen, Ulrich, Bier, Henning, Dott, Wolfgang, Mücke, Hans‐Guido, Straff, Wolfgang, Wurpts, Gerda, Yazdi, Amir S., Chaker, Adam, Röseler, Stefani T. M.

“…Background Diagnosis of pollen allergies is mainly based on test allergens for skin prick testing. In the minimum battery of test inhalant allergens…”
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A Skin-Like Cytochrome P450 Cocktail Activates Prohaptens to Contact Allergenic Metabolites by Bergström, Moa Andresen, Ott, Hagen, Carlsson, Anna, Neis, Mark, Zwadlo-Klarwasser, Gabriele, Jonsson, Charlotte A.M., Merk, Hans F., Karlberg, Ann-Therese, Baron, Jens M.

“…Allergic contact dermatitis is a complex syndrome representing immunological responses to cutaneous exposure to protein-reactive chemicals. Although many…”
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False‐positive test results in diagnosing allergy to glatiramer acetate: Case report and a systematic literature review by Röseler, Stefani, Leufgens, Friederike, Merk, Hans F., Baron, Jens M., Moll‐Slodowy, Silke, Wurpts, Gerda, Balakirski, Galina

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Evaluation of the sensitizing potential of antibiotics in vitro using the human cell lines THP-1 and MUTZ-LC and primary monocyte‐derived dendritic cells by Sebastian, Katrin, Ott, Hagen, Zwadlo-Klarwasser, Gabriele, Skazik-Voogt, Claudia, Marquardt, Yvonne, Czaja, Katharina, Merk, Hans F., Baron, Jens Malte

“…Since the 7th amendment to the EU cosmetics directive foresees a complete ban on animal testing, alternative in vitro methods have been established to evaluate…”
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P-Glycoprotein (ABCB1) expression in human skin is mainly restricted to dermal components by Skazik, Claudia, Wenzel, Jörg, Marquardt, Yvonne, Kim, Arianna, Merk, Hans F., Bickers, David R., Baron, Jens M.

“…:  Several transport proteins are constitutively expressed in skin cells, but the putative role of the ABC transporter P‐glycoprotein (P‐gp) in human skin is…”
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Expression of Multiple Cytochrome P450 Enzymes and Multidrug Resistance-Associated Transport Proteins in Human Skin Keratinocytes by Baron, Jens M., Höller, Daniela, Schiffer, Ruth, Frankenberg, Silke, Neis, Mark, Merk, Hans F., Jugert, Frank K.

“…Cytochrome P450 enzymes metabolize various endogenous and exogenous small molecular weight compounds. Transport-associated proteins, such as P-glycoprotein,…”
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Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts by Wiederholt, Tonio, Heise, Ruth, Skazik, Claudia, Marquardt, Yvonne, Joussen, Sylvia, Erdmann, Kati, Schröder, Henning, Merk, Hans F., Baron, Jens Malte

“…:  Topical application of pantothenate is widely used in clinical practice for wound healing. Previous studies identified a positive effect of pantothenate on…”
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Active Transport of Contact Allergens and Steroid Hormones in Epidermal Keratinocytes is Mediated by Multidrug Resistance Related Proteins by Heise, Ruth, Skazik, Claudia, Rodriguez, Felipe, Stanzel, Sven, Marquardt, Yvonne, Joussen, Sylvia, Wendel, Andreas F., Wosnitza, Melanie, Merk, Hans F., Baron, Jens M.

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13-cis Retinoic Acid Exerts its Specific Activity on Human Sebocytes through Selective Intracellular Isomerization to All-trans Retinoic Acid and Binding to Retinoid Acid Receptors by Tsukada, Miki, Schröder, Mandy, Orfanos, Constantin E., Zouboulis, Christos C., Roos, Thomas C., Chandraratna, Roshantha A.S., Reichert, Uwe, Merk, Hans F.

“…Despite its potent biologic effect on human sebocytes, 13-cis retinoic acid exhibits low binding affinity for cellular retinoic acid binding proteins and…”
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Digenic Inheritance of Mutations in the Coproporphyrinogen Oxidase and Protoporphyrinogen Oxidase Genes in a Unique Type of Porphyria by van Tuyll van Serooskerken, Anne Moniek, de Rooij, Felix W., Edixhoven, Annie, Bladergroen, Reno S., Baron, Jens M., Joussen, Sylvia, Merk, Hans F., Steijlen, Peter M., Poblete-Gutiérrez, Pamela, te Velde, Kornelis, Paul Wilson, J.H., Koole, Rita H., van Geel, Michel, Frank, Jorge

“…The simultaneous dysfunction of two enzymes within the heme biosynthetic pathway in a single patient is rare. Not more than 15 cases have been reported. A…”
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