Search Results - "Merikhian, Parnaz"
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Triple-negative breast cancer: understanding Wnt signaling in drug resistance
Published in Cancer cell international (10-08-2021)“…Abstract Triple-negative breast cancer (TNBC) is not as prevalent as hormone receptor or HER2-positive breast cancers and all receptor tests come back…”
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Crosstalk between MUC1 and VEGF in angiogenesis and metastasis: a review highlighting roles of the MUC1 with an emphasis on metastatic and angiogenic signaling
Published in Cancer cell international (09-04-2021)“…VEGF and its receptor family (VEGFR) members have unique signaling transduction system that play significant roles in most pathological processes, such as…”
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MUC1 is a potential target to overcome trastuzumab resistance in breast cancer therapy
Published in Cancer cell international (05-03-2022)“…Although resistance is its major obstacle in cancer therapy, trastuzumab is the most successful agent in treating epidermal growth factor receptor 2 positive…”
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Monoclonal antibody‐based therapeutics, targeting the epidermal growth factor receptor family: from herceptin to Pan HER
Published in Journal of pharmacy and pharmacology (01-07-2018)“…Objectives Monoclonal antibody‐based of cancer therapy has been considered as one of the most successful therapeutic strategies for both haematologic…”
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Recombinant nanobody against MUC1 tandem repeats inhibits growth, invasion, metastasis, and vascularization of spontaneous mouse mammary tumors
Published in Molecular oncology (01-01-2022)“…Alteration in glycosylation pattern of MUC1 mucin tandem repeats during carcinomas has been shown to negatively affect adhesive properties of malignant cells…”
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Anti-cancer therapeutic strategies based on HGF/MET, EpCAM, and tumor-stromal cross talk
Published in Cancer cell international (19-08-2022)“…Abstract As an intelligent disease, tumors apply several pathways to evade the immune system. It can use alternative routes to bypass intracellular signaling…”
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MUC1 induces tamoxifen resistance in estrogen receptor-positive breast cancer
Published in Expert review of anticancer therapy (03-07-2017)“…Introduction: Tamoxifen, as an essential therapeutic tool in the treatment of estrogen receptor-positive breast cancer, has been available for the past three…”
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