Search Results - "Merezhko, Maria"

Mechanisms of secretion and spreading of pathological tau protein by Brunello, Cecilia A., Merezhko, Maria, Uronen, Riikka-Liisa, Huttunen, Henri J.

“…Accumulation of misfolded and aggregated forms of tau protein in the brain is a neuropathological hallmark of tauopathies, such as Alzheimer’s disease and…”
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Secretion of Tau via an Unconventional Non-vesicular Mechanism by Merezhko, Maria, Brunello, Cecilia A., Yan, Xu, Vihinen, Helena, Jokitalo, Eija, Uronen, Riikka-Liisa, Huttunen, Henri J.

“…Tauopathies are characterized by cerebral accumulation of Tau protein aggregates that appear to spread throughout the brain via a cell-to-cell transmission…”
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The Cell Biology of Tau Secretion by Merezhko, Maria, Uronen, Riikka-Liisa, Huttunen, Henri J.

“…The progressive accumulation and spread of misfolded tau protein in the nervous system is the hallmark of tauopathies, progressive neurodegenerative diseases…”
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Multiplex assay for live-cell monitoring of cellular fates of amyloid-β precursor protein (APP) by Merezhko, Maria, Muggalla, Pranuthi, Nykänen, Niko-Petteri, Yan, Xu, Sakha, Prasanna, Huttunen, Henri J

“…Amyloid-β precursor protein (APP) plays a central role in pathogenesis of Alzheimer's disease. APP has a short half-life and undergoes complex proteolytic…”
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Live-cell monitoring of protein localization to membrane rafts using protein-fragment complementation by Merezhko, Maria, Pakarinen, Emmi, Uronen, Riikka-Liisa, Huttunen, Henri J

“…The plasma membrane consists of a variety of discrete domains differing from the surrounding membrane in composition and properties. Selective partitioning of…”
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