Search Results - "Meredith, Gloria E."

Behavioral models of Parkinson's disease in rodents: A new look at an old problem by Meredith, Gloria E., Kang, Un Jung

“…The circuitry important for voluntary movement is influenced by dopamine from the substantia nigra and regulated by the nigrostriatal system. The basal ganglia…”
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The structural basis for mapping behavior onto the ventral striatum and its subdivisions by Meredith, Gloria E., Baldo, Brian A., Andrezjewski, Matthew E., Kelley, Ann E.

“…The striatum can be divided into dorsal (caudate-putamen) and ventral parts. In the ventral division, the nucleus accumbens, which subserves adaptive and…”
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Fos After Single and Repeated Self-Administration of Cocaine and Saline in the Rat: Emphasis on the Basal Forebrain and Recalibration of Expression by ZAHM, Daniel S, BECKER, Mary L, FREIMAN, Alexander, STRAUCH, Sara, DEGARMO, Beth, GEISLER, Stefanie, MEREDITH, Gloria E, MARINELLI, Michela

“…The effects of addictive psychostimulant drugs on the brain change over repeated administrations. We evaluated a large sample of brain structures, particularly…”
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Amphetamine-Induced Place Preference and Conditioned Motor Sensitization Requires Activation of Tyrosine Kinase Receptors in the Hippocampus by Shen, Fei, Meredith, Gloria E, Napier, T. Celeste

“…The environmental context in which abused drugs are taken contribute to the drug experience and is a powerful and persistent stimulus to elicit memories of…”
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Prominent Activation of Brainstem and Pallidal Afferents of the Ventral Tegmental Area by Cocaine by GEISLER, Stefanie, MARINELLI, Michela, DEGARMO, Beth, BECKER, Mary L, FREIMAN, Alexander, BEALES, Mitch, MEREDITH, Gloria E, ZAHM, Daniel S

“…Blockade of monoamine transporters by cocaine should not necessarily lead to certain observed consequences of cocaine administration, including increased…”
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Brain-derived neurotrophic factor expression is increased in the rat amygdala, piriform cortex and hypothalamus following repeated amphetamine administration by Meredith, Gloria E, Callen, Shannon, Scheuer, Deborah A

“…The amygdala plays an important role in the regulation of motivational states, especially those associated with addiction. The amygdala also expresses high…”
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The role of oxidative stress in the dysregulation of gene expression and protein metabolism in neurodegenerative disease by Potashkin, Judith A, Meredith, Gloria E

“…There are few examples for which the genetic basis for neurodegenerative disease has been identified. For the majority of these disorders, the key to their…”
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MPTP mouse models of Parkinson's disease: an update by Meredith, Gloria E, Rademacher, David J

“…Among the most widely used models of Parkinson's disease (PD) are those that employ toxins, especially 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)…”
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The ultrastructural distribution of alpha-synuclein-like protein in normal mouse brain by Totterdell, Susan, Hanger, Diane, Meredith, Gloria E

“…The synaptic protein alpha-synuclein is found throughout the brain, although its function remains ill-defined. Abnormal accumulations of alpha-synuclein have…”
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Animal models of Parkinson’s disease progression by Meredith, Gloria E., Sonsalla, Patricia K., Chesselet, Marie-Francoise

“…Parkinson’s disease (PD) is a progressive neurodegenerative disorder whose etiology is not understood. This disease occurs both sporadically and through…”
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'Rejuvenation' protects neurons in mouse models of Parkinson's disease by Tkatch, Tatiana, Chan, C. Savio, Surmeier, D. James, Rick, Caroline, Guzman, Jaime N, Meredith, Gloria E, Ilijic, Ema, Mercer, Jeff N

“…Why dopamine-containing neurons of the brain's substantia nigra pars compacta die in Parkinson's disease has been an enduring mystery. Our studies suggest that…”
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Aberrant restoration of spines and their synapses in L-DOPA-induced dyskinesia: involvement of corticostriatal but not thalamostriatal synapses by Zhang, Yiyue, Meredith, Gloria E, Mendoza-Elias, Nasya, Rademacher, David J, Tseng, Kuei Y, Steece-Collier, Kathy

“…We examined the structural plasticity of excitatory synapses from corticostriatal and thalamostriatal pathways and their postsynaptic targets in adult…”
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Modeling PD pathogenesis in mice: Advantages of a chronic MPTP protocol by Meredith, Gloria E, Totterdell, Susan, Potashkin, Judith A, Surmeier, D. James

“…Abstract Formidable challenges for Parkinson's disease (PD) research are to understand the processes underlying nigrostriatal degeneration and how to protect…”
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Quantitative proteomic analysis of mitochondrial proteins: relevance to Lewy body formation and Parkinson's disease by Jin, Jinghua, Meredith, Gloria E., Chen, Leo, Zhou, Yong, Xu, Jing, Shie, Feng-Shiun, Lockhart, Paul, Zhang, Jing

“…The mechanisms underlying Parkinson's disease (PD) and Lewy body (LB) formation, a pathological hallmark of PD, are incompletely understood; however,…”
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Different roles of BDNF in nucleus accumbens core versus shell during the incubation of cue-induced cocaine craving and its long-term maintenance by Li, Xuan, DeJoseph, M R, Urban, Janice H, Bahi, Amine, Dreyer, Jean-Luc, Meredith, Gloria E, Ford, Kerstin A, Ferrario, Carrie R, Loweth, Jessica A, Wolf, Marina E

“…Brain-derived neurotrophic factor (BDNF) contributes to diverse types of plasticity, including cocaine addiction. We investigated the role of BDNF in the rat…”
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Effects of context-drug learning on synaptic connectivity in the basolateral nucleus of the amygdala in rats by Rademacher, David J., Mendoza-Elias, Nasya, Meredith, Gloria E.

“…Context‐drug learning produces structural and functional synaptic changes in the circuitry of the basolateral nucleus of the amygdala (BLA). However, how the…”
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Repeated amphetamine administration induces Fos in prefrontal cortical neurons that project to the lateral hypothalamus but not the nucleus accumbens or basolateral amygdala by Morshedi, Maud M., Meredith, Gloria E.

“…Rationale The development of sensitization to amphetamine (AMPH) is dependent on increases in excitatory outflow from the medial prefrontal cortex (mPFC) to…”
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Amphetamine-Associated Contextual Learning Is Accompanied by Structural and Functional Plasticity in the Basolateral Amygdala by Rademacher, David J, Rosenkranz, J. Amiel, Morshedi, Maud M, Sullivan, Elyse M, Meredith, Gloria E

“…Drug seeking and the vulnerability to relapse occur when individuals are exposed to an environment with sensory cues in which drug taking has occurred. Memory…”
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Differential laminar effects of amphetamine on prefrontal parvalbumin interneurons by Morshedi, M.M, Meredith, Gloria E

“…Abstract The increase in excitatory outflow from the medial prefrontal cortex is critical to the development of sensitization to amphetamine. There is evidence…”
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The neural substrates of amphetamine conditioned place preference: implications for the formation of conditioned stimulus-reward associations by Rademacher, David J., Kovacs, Beatrix, Shen, Fei, Napier, T. Celeste, Meredith, Gloria E.

“…Associations formed between conditioned stimuli and drug reward are major contributors in human drug addiction. To better understand the brain changes that…”
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