Search Results - "Meredith, Elizabeth"

Intranasal Delivery of Proteins and Peptides in the Treatment of Neurodegenerative Diseases by Meredith, M. Elizabeth, Salameh, Therese S., Banks, William A.

“…The blood–brain barrier (BBB) is a major impediment to the therapeutic delivery of peptides and proteins to the brain. Intranasal delivery often provides a…”
Get full text

Countering the advert effects of lung cancer on the anticancer potential of dendritic cell populations reinstates sensitivity to anti-PD-1 therapy by Brassard, Julyanne, Gill, Meredith Elizabeth, Bernatchez, Emilie, Desjardins, Véronique, Roy, Joanny, Joubert, Philippe, Marsolais, David, Blanchet, Marie-Renée

“…Lung cancer is the leading cause of cancer-related deaths. While the recent use of immune checkpoint inhibitors significantly improves patient outcomes,…”
Get full text

Ascorbate reverses high glucose- and RAGE-induced leak of the endothelial permeability barrier by Meredith, M. Elizabeth, Qu, Zhi-Chao, May, James M.

“…•Endothelial cells accumulate millimolar concentrations of ascorbate after one hour.•Ascorbate decreases permeability under basal and high glucose…”
Get full text

Hepatic energy state is regulated by glucagon receptor signaling in mice by Berglund, Eric D, Lee-Young, Robert S, Lustig, Daniel G, Lynes, Sara E, Donahue, E Patrick, Camacho, Raul C, Meredith, M Elizabeth, Magnuson, Mark A, Charron, Maureen J, Wasserman, David H

“…The hepatic energy state, defined by adenine nucleotide levels, couples metabolic pathways with energy requirements. This coupling is fundamental in the…”
Get full text

Low ascorbic acid and increased oxidative stress in gulo(−/−) mice during development by Harrison, Fiona E, Meredith, M. Elizabeth, Dawes, Sean M, Saskowski, Jeanette L, May, James M

“…Abstract Vitamin C (ascorbic acid, AA) depletion during prenatal and postnatal development can lead to oxidative stress in the developing brain and other…”
Get full text

Identification and Quantification of Base Flow Using Carbon Isotopes by Meredith, Elizabeth L., Kuzara, Shawn L.

“…Six surface water samples from locations along Otter Creek in Southeastern Montana and a groundwater sample from a nearby monitoring well completed in the…”
Get full text

Dopamine Targets Cycling B Cells Independent of Receptors/Transporter for Oxidative Attack: Implications for Non-Hodgkin's Lymphoma by Meredith, Elizabeth J., Holder, Michelle J., Rosén, Anders, Lee, Adrian Drake, Dyer, Martin J. S., Barnes, Nicholas M., Gordon, John

“…Human B lymphocytes and derived lines from a spectrum of B cell malignancy were studied for expression of dopaminergic pathway components and for their…”
Get full text

Close encounters of the monoamine kind: immune cells betray their nervous disposition by Meredith, Elizabeth J., Chamba, Anita, Holder, Michelle J., Barnes, Nicholas M., Gordon, John

“…Summary Here we review the evidence for immune cells expressing multiple components of the serotonergic and dopaminergic systems that are more commonly…”
Get full text

The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential anti-tumor target for psychotropics by Meredith, Elizabeth J, Holder, Michelle J, Chamba, Anita, Challa, Anita, Drake-Lee, Adrian, Bunce, Christopher M, Drayson, Mark T, Pilkington, Geoffrey, Blakely, Randy D, Dyer, Martin J S, Barnes, Nicholas M, Gordon, John

“…Following our previous description of the serotonin transporter (SERT) acting as a conduit to 5-hydroxytryptamine (5-HT)-mediated apoptosis, specifically in…”
Get full text

Quantifying irrigation recharge sources using groundwater modeling by Meredith, Elizabeth, Blais, Nicole

“…•Recharge to the modeled aquifer is mainly canal leakage not irrigation infiltration.•An irrigation canal also serves as a significant drain that prevents…”
Get full text

Mechanisms of ascorbic acid stimulation of norepinephrine synthesis in neuronal cells by May, James M., Qu, Zhi-chao, Meredith, M. Elizabeth

“…► Ascorbic acid enhances norepinephrine synthesis in SH-SY5Y neuroblastoma cells. ► Norepinephrine synthesis increases linearly with intracellular ascorbate. ►…”
Get full text

Increased expression of SVCT2 in a new mouse model raises ascorbic acid in tissues and protects against paraquat-induced oxidative damage in lung by Harrison, Fiona Edith, Best, Jennifer Lee, Meredith, Martha Elizabeth, Gamlin, Clare Ruth, Borza, Dorin-Bogdan, May, James Marion, May, James Michael

“…A new transgenic mouse model for global increases in the Sodium Dependent Vitamin C transporter 2 (SVCT2) has been generated. The SVCT2-Tg mouse shows…”
Get full text

Differential regulation of the ascorbic acid transporter SVCT2 during development and in response to ascorbic acid depletion by Meredith, M. Elizabeth, Harrison, Fiona E., May, James M.

“…► SVCT2 expression levels in brain are low during development and increase with age. ► In liver, SVCT2 levels are low during embryogenesis and increase…”
Get full text

Regulation of embryonic neurotransmitter and tyrosine hydroxylase protein levels by ascorbic acid by Meredith, M.Elizabeth, May, James M

“…Abstract Scope : Ascorbic acid (ascorbate) is required to recycle tetrahydrobiopterin, which is necessary for neurotransmitter synthesis by the rate-limiting…”
Get full text

Coal aquifer contribution to streams in the Powder River Basin, Montana by Meredith, Elizabeth Brinck

“…•Coalbed methane and coalmine production can reduce groundwater baseflow to streams.•Baseflow from coal aquifers is quantified using geochemical and isotope…”
Get full text

Correction: Increased Expression of SVCT2 in a New Mouse Model Raises Ascorbic Acid in Tissues and Protects against Paraquat-Induced Oxidative Damage in Lung by Harrison, Fiona Edith, Best, Jennifer Lee, Meredith, Martha Elizabeth, Gamlin, Clare Ruth, Borza, Dorin-Bogdan, May, James Michael

Get full text

Altering the dendritic cell signature in the lung: a new adjuvant to immune checkpoint inhibitor therapies? by Brassard, Julyanne, Bernatchez, Emilie, Gill, Meredith Elizabeth, Joubert, Philippe, Blanchet, Marie-Renée

“…Abstract Lung cancer is the leading cause of cancer-related death. While the recent introduction of immune checkpoint immunotherapies significantly improves…”
Get full text

Accurately Determining Groundwater Sulfate Concentrations from Reclaimed Landscapes with Conductometric Titrations by Yiyen, Galip, Duck, Kodie V., Meredith, Elizabeth L., Walker, Robert A.

“…Conductometric titrations were used to measure sulfate concentrations in ground and surface water samples taken from land reclaimed after open-air coal mining…”
Get full text

Intracellular ascorbate tightens the endothelial permeability barrier through Epac1 and the tubulin cytoskeleton by Parker, William H, Rhea, Elizabeth Meredith, Qu, Zhi-Chao, Hecker, Morgan R, May, James M

“…Vitamin C, or ascorbic acid, both tightens the endothelial permeability barrier in basal cells and also prevents barrier leak induced by inflammatory agents…”
Get more information

Response to ‘Orbital Wegener's granulomatosis as the initial presentation in a 9-year-old child’ by Meredith, Elizabeth, Hull, Richard

Get full text