Search Results - "Mercurio, C."
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Hippocampal Excitability Increases during the Estrous Cycle in the Rat: A Potential Role for Brain-Derived Neurotrophic Factor
Published in The Journal of neuroscience (17-12-2003)“…To test the hypothesis that induction of BDNF may contribute to changes in hippocampal excitability occurring during the female reproductive cycle, we examined…”
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2
Valproic acid induces differentiation and transient tumor regression, but spares leukemia-initiating activity in mouse models of APL
Published in Leukemia (01-07-2012)“…Aberrant histone acetylation was physiopathologically associated with the development of acute myeloid leukemias (AMLs). Reversal of histone deacetylation by…”
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3
New limits on the ultrahigh energy cosmic neutrino flux from the ANITA experiment
Published in Physical review letters (31-07-2009)“…We report initial results of the first flight of the Antarctic Impulsive Transient Antenna (ANITA-1) 2006-2007 Long Duration Balloon flight, which searched for…”
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4
Characterizing metastatic uveal melanoma patients who develop symptomatic brain metastases
Published in Frontiers in oncology (08-09-2022)“…Metastatic uveal melanoma (mUM) is an advanced ocular malignancy characterized by a hepatotropic pattern of spread. As the incidence of brain metastases (BM)…”
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5
EPA-0398 – Parent-training intervention among a group of parents of children with ADHD
Published in European psychiatry (2014)“…Introduction Up to today, there are experimental evidences pointing out the usefulness of cognitive-behavioral interventions for the treatment of children with…”
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Anti‐tumour efficacy on glioma models of PHA‐848125, a multi‐kinase inhibitor able to cross the blood–brain barrier
Published in British journal of pharmacology (01-05-2013)“…Background and Purpose Malignant gliomas, the most common primary brain tumours, are highly invasive and neurologically destructive neoplasms with a very bad…”
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Characterization of a novel KDM1A/LSD1 inhibitor DDP_38003 in preclinical models of human and murine acute myeloid leukemia
Published in European journal of cancer (1990) (01-12-2016)“…KDM1A (LSD1) is a flavin adenine dinucleotide dependent histone demethylase, responsible for the demethylation of mono and dimethyl lysine 4 on histone H3. As…”
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New reversible inhibitors of histone lysine demethylase (KDM1A/LSD1). From high throughput screening to the identification of low nanomolar inhibitors with cellular activity
Published in European journal of cancer (1990) (01-12-2016)“…Background: Lysine specific demethylase 1 KDM1A (LSD1) is an epigenetic eraser that regulates histone methylation at residues K4 and K9 and plays an important…”
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EPA-0401 – The emotional and behavioral regulation among two groups of ADHD children: an experience
Published in European psychiatry (2014)“…The recent research (Barkley, 1997) showed a significant relation between ADHD and difficulties in emotional regulation among primary school children. During…”
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10
Design, synthesis and preliminary evaluation of a series of histone deacetylase inhibitors carrying a benzodiazepine ring
Published in European journal of medicinal chemistry (01-08-2013)“…A series of new histone deacetylase inhibitors were designed and synthesized based on hybridization between SAHA or oxamflatin and…”
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571 Novel potent inhibitors of the Histone Demethylase KDM1A: Synthesis, pharmacological evaluation and in vivo activity
Published in European journal of cancer (1990) (01-11-2014)Get full text
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12
Adult Neurogenesis and the Initiation of Social Aggression in Male Mice
Published in Hippocampus (01-12-2024)“…ABSTRACT The hippocampus is important for social behavior and exhibits unusual structural plasticity in the form of continued production of new granule neurons…”
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13
Characteristics of Four Upward-Pointing Cosmic-Ray-like Events Observed with ANITA
Published in Physical review letters (12-08-2016)“…We report on four radio-detected cosmic-ray (CR) or CR-like events observed with the Antarctic Impulsive Transient Antenna (ANITA), a NASA-sponsored…”
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14
Drf1, a novel regulatory subunit for human Cdc7 kinase
Published in The EMBO journal (17-06-2002)“…Studies in model organisms have contributed to elucidate multiple levels at which regulation of eukaryotic DNA replication occurs. Cdc7, an evolutionarily…”
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15
A role for hippocampal adult neurogenesis in shifting attention toward novel stimuli
Published in Behavioural brain research (30-12-2019)“…•Adult neurogenesis increases orienting toward a novel stimulus during focused activity.•Rats without ongoing neurogenesis orient normally when they are…”
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16
Preeclampsia: Long-term effects on pediatric disability
Published in Journal of neonatal-perinatal medicine (24-03-2016)“…Preeclampsia affects up to 10% of pregnancies worldwide and is one of the main causes of fetal morbidity and mortality. Although it has been linked to…”
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A new light on secukinumab in pediatric psoriasis
Published in Italian journal of dermatology and venereology (01-08-2024)Get more information
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18
Seizure susceptibility in intact and ovariectomized female rats treated with the convulsant pilocarpine
Published in Experimental neurology (01-11-2005)“…Despite numerous neuroendocrinological studies of seizures, the influence of estrogen and progesterone on seizures and epilepsy remains unclear. This may be…”
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Energy and flux measurements of ultra-high energy cosmic rays observed during the first ANITA flight
Published in Astroparticle physics (01-04-2016)“…The first flight of the Antarctic Impulsive Transient Antenna (ANITA) experiment recorded 16 radio signals that were emitted by cosmic-ray induced air showers…”
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20
Observation of ultrahigh-energy cosmic rays with the ANITA balloon-borne radio interferometer
Published in Physical review letters (08-10-2010)“…We report the observation of 16 cosmic ray events with a mean energy of 1.5 × 10¹⁹ eV via radio pulses originating from the interaction of the cosmic ray air…”
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