Search Results - "Mercogliano, Florencia"

Tumor Necrosis Factor α Blockade: An Opportunity to Tackle Breast Cancer by Mercogliano, María Florencia, Bruni, Sofía, Elizalde, Patricia V, Schillaci, Roxana

“…Breast cancer is the most frequently diagnosed cancer and the principal cause of mortality by malignancy in women and represents a main problem for public…”
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JUVENILE EXPOSURE TO A HIGH FAT DIET PROMOTES BEHAVIORAL AND LIMBIC ALTERATIONS IN THE ABSENCE OF OBESITY by Vinuesa, Angeles, Pomilio, Carlos, Menafra, Martin, Bonaventura, Maria Marta, Garay, Laura, Mercogliano, María Florencia, Lantos, Roxana Schillaci Victoria Lux, Brites, Fernando, Beauquis, Juan, Saravia, Flavia

“…Highlights • Mice fed with high fat diet (HFD) developed hyperinsulinemia, dyslipidemia and prothrombotic risk. • The liver of HDF mice showed high…”
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Cancer immune exclusion: breaking the barricade for a successful immunotherapy by Bruni, Sofia, Mercogliano, María Florencia, Mauro, Florencia Luciana, Cordo Russo, Rosalia Inés, Schillaci, Roxana

“…Immunotherapy has changed the course of cancer treatment. The initial steps were made through tumor-specific antibodies that guided the setup of an antitumor…”
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Emerging Targeted Therapies for HER2-Positive Breast Cancer by Mercogliano, María Florencia, Bruni, Sofía, Mauro, Florencia Luciana, Schillaci, Roxana

“…Breast cancer is the most common cancer in women and the leading cause of death. HER2 overexpression is found in approximately 20% of breast cancers and is…”
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p42/p44 MAPK-mediated Stat3Ser727 phosphorylation is required for progestin-induced full activation of Stat3 and breast cancer growth by Tkach, Mercedes, Rosemblit, Cinthia, Rivas, Martín A, Proietti, Cecilia J, Díaz Flaqué, María Celeste, Mercogliano, María Florencia, Beguelin, Wendy, Maronna, Esteban, Guzmán, Pablo, Gercovich, Felipe G, Deza, Ernesto Gil, Elizalde, Patricia V, Schillaci, Roxana

“…Stat3 is a signaling node for multiple oncogenic pathways and is therefore frequently active in breast cancer. As experimental and clinical evidence reveals…”
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Harnessing Tumor Necrosis Factor Alpha to Achieve Effective Cancer Immunotherapy by Mercogliano, María Florencia, Bruni, Sofía, Mauro, Florencia, Elizalde, Patricia Virginia, Schillaci, Roxana

“…Tumor necrosis factor alpha (TNFα) is a pleiotropic cytokine known to have contradictory roles in oncoimmunology. Indeed, TNFα has a central role in the onset…”
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FXYD5/Dysadherin, a Biomarker of Endometrial Cancer Myometrial Invasion and Aggressiveness: Its Relationship With TGF-β1 and NF-κB Pathways by Besso, María José, Rosso, Marina, Lapyckyj, Lara, Moiola, Cristian Pablo, Matos, María Laura, Mercogliano, María Florencia, Schillaci, Roxana, Reventos, Jaume, Colas, Eva, Gil-Moreno, Antonio, Wernicke, Alejandra, Orti, Roberto, Vazquez-Levin, Mónica Hebe

“…Endometrial cancer (EC) is the second most common gynecological cancer worldwide. Myometrial invasion (MI) is a key event in EC dissemination. This study aimed…”
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Inhibition of MHC‐I by Brucella abortus is an early event during infection and involves EGFR pathway by Velásquez, Lis N, Milillo, M Ayelén, Delpino, M Victoria, Trotta, Aldana, Mercogliano, M Florencia, Pozner, Roberto G, Schillaci, Roxana, Elizalde, Patricia V, Giambartolomei, Guillermo H, Barrionuevo, Paula

“…Brucella abortus is able to persist inside the host despite the development of potent CD8+ T‐cell responses. We have recently reported the ability of B…”
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Retraction Note: Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy by Flaqué, María C. Díaz, Galigniana, Natalia M, Béguelin, Wendy, Vicario, Rocío, Proietti, Cecilia J, Russo, Rosalía Cordo, Rivas, Martín A, Tkach, Mercedes, Guzmán, Pablo, Roa, Juan C, Maronna, Esteban, Pineda, Viviana, Muéoz, Sergio, Mercogliano, María Florencia, Charreau, Eduardo H, Yankilevich, Patricio, Schillaci, Roxana, Elizalde, Patricia V

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Corrigendum: FXYD5/Dysadherin, a biomarker of endometrial cancer myometrial invasion and aggressiveness: its relationship with TGF-β1 and NF-κB pathways by Besso, María José, Rosso, Marina, Lapyckyj, Lara, Moiola, Cristian Pablo, Matos, María Laura, Mercogliano, María Florencia, Schillaci, Roxana, Reventos, Jaume, Colas, Eva, Gil-Moreno, Antonio, Wernicke, Alejandra, Orti, Roberto, Vazquez-Levin, Mónica Hebe

“…[This corrects the article DOI: 10.3389/fonc.2019.01306.]…”
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Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy by Díaz Flaqué, María C, Galigniana, Natalia M, Béguelin, Wendy, Vicario, Rocío, Proietti, Cecilia J, Russo, Rosalía, Rivas, Martín A, Tkach, Mercedes, Guzmán, Pablo, Roa, Juan C, Maronna, Esteban, Pineda, Viviana, Muñoz, Sergio, Mercogliano, María, Charreau, Eduardo H, Yankilevich, Patricio, Schillaci, Roxana, Elizalde, Patricia V

“…The role of the progesterone receptor (PR) in breast cancer remains a major clinical challenge. Although PR induces mammary tumor growth, its presence in…”
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RETRACTED ARTICLE: Progesterone receptor assembly of a transcriptional complex along with activator protein 1, signal transducer and activator of transcription 3 and ErbB-2 governs breast cancer growth and predicts response to endocrine therapy by Díaz Flaqué, María C, Galigniana, Natalia M, Béguelin, Wendy, Vicario, Rocío, Proietti, Cecilia J, Russo, Rosalía Cordo, Rivas, Martín A, Tkach, Mercedes, Guzmán, Pablo, Roa, Juan C, Maronna, Esteban, Pineda, Viviana, Muñoz, Sergio, Mercogliano, María Florencia, Charreau, Eduardo H, Yankilevich, Patricio, Schillaci, Roxana, Elizalde, Patricia V

“…Abstract Introduction The role of the progesterone receptor (PR) in breast cancer remains a major clinical challenge. Although PR induces mammary tumor growth,…”
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Heregulin Co-opts PR Transcriptional Action Via Stat3 Role As a Coregulator to Drive Cancer Growth by Proietti, Cecilia J, Izzo, Franco, Díaz Flaqué, María Celeste, Cordo Russo, Rosalía, Venturutti, Leandro, Mercogliano, María Florencia, De Martino, Mara, Pineda, Viviana, Muñoz, Sergio, Guzmán, Pablo, Roa, Juan C, Schillaci, Roxana, Elizalde, Patricia V

“…Accumulated findings have demonstrated the presence of bidirectional interactions between progesterone receptor (PR) and the ErbB family of receptor tyrosine…”
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Abstract PO2-18-05: Blocking soluble TNF to Improve potency of trastuzumab deruxtecan by increasing internalization and antitumor innate immune response in a resistant HER2-positive breast cancer model by Bruni, Sofia, Mauro, Florencia, Naveiro, Sofia, Cordo-Russo, Rosalia, Dupont, Agustina, Florencia, Mercogliano María, Schillaci, Roxana

“…Abstract Background Trastuzumab deruxtecan (T-DXd) administration improves response for patients with HER2-positive metastatic breast cancer (HER2+ BC)…”
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Pituitary stem cells: past, present and future perspectives by Pérez Millán, María Inés, Cheung, Leonard Y. M., Mercogliano, Florencia, Camilletti, Maria Andrea, Chirino Felker, Gonzalo T., Moro, Lucia N., Miriuka, Santiago, Brinkmeier, Michelle L., Camper, Sally A.

“…Pituitary cells that express the transcription factor SOX2 are stem cells because they can self-renew and differentiate into multiple pituitary…”
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Abstract P1-11-12: Soluble TNFα blockade enhances trastuzumab deruxtecan antitumor effect in HER2-positive breast cancer model by Bruni, Sofia, Mauro, Florencia, Proietti, Cecilia, Cordo-Russo, Rosalia, Florencia, Mercogliano María, Schillaci, Roxana

“…Abstract Background. Clinical trials have demonstrated that trastuzumab deruxtecan (T-DXd) provides a durable responses for patients with HER2-positive and…”
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Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth by Izzo, Franco, Mercogliano, Florencia, Venturutti, Leandro, Tkach, Mercedes, Inurrigarro, Gloria, Schillaci, Roxana, Cerchietti, Leandro, Elizalde, Patricia V, Proietti, Cecilia J

“…The transcription factor GATA3 is involved in mammary gland development and is crucial for the maintenance of the differentiated status of luminal epithelial…”
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ODP438 Canonical and Non-canonical Function of EZH2 in Progesterone Receptor Target Genes in Breast Cancer by Elizalde, Patricia, Belmonte, Martina, Cenciarini, Mauro, Deamicis, Agustina Roldan, Madera, Santiago, Mercogliano, Florencia, Mauro, Florencia, Bruni, Sofia, Russo, Rosalía Cordo, Schillaci, Roxana, Proietti, Cecilia

“…Abstract Enhancer of Zeste homolog 2 (EZH2) is a histone methyltransferase which catalyzes the trimethylation of lysine 27 of histone H3 (H3K27me3), an…”
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Comprehensive Identification of Pathogenic Gene Variants in Patients With Neuroendocrine Disorders by Vishnopolska, Sebastian Alexis, Mercogliano, Maria Florencia, Camilletti, Maria Andrea, Mortensen, Amanda Helen, Braslavsky, Debora, Keselman, Ana, Bergadá, Ignacio, Olivieri, Federico, Miranda, Lucas, Marino, Roxana, Ramírez, Pablo, Pérez Garrido, Natalia, Patiño Mejia, Helen, Ciaccio, Marta, Di Palma, Maria Isabel, Belgorosky, Alicia, Martí, Marcelo Adrian, Kitzman, Jacob Otto, Camper, Sally Ann, Pérez-Millán, Maria Ines

“…Abstract Purpose Congenital hypopituitarism (CH) can present in isolation or with other birth defects. Mutations in multiple genes can cause CH, and the use of…”
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OR17-02 Combining Transcriptomics And Proteomics To Unveil Possible PROP1 Interactors During Embryonic Pituitary Development by Garcia, Lucia Iglesias, Mercogliano, María Florencia, Schuster, Claudio, Cheung, Leonard, Camper, Sally Ann, Marti, Marcelo, Perez-Millan, Maria Ines

“…Abstract Disclosure: L. Iglesias Garcia: None. M.F. Mercogliano: None. C. Schuster: None. L. Cheung: None. S.A. Camper: None. M. Marti: None. M.I…”
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