Search Results - "Mercier, Cedric"
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Making time perception shorter with pitch and interval patterns
Published in Behaviour & information technology (25-01-2024)“…The average attention span of humans is decreasing. To adapt to the change, researchers investigate visual and auditory techniques that alter the perception of…”
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Common Strategy for Adult and Pediatric Medulloblastoma: A Multicenter Series of 253 Adults
Published in International journal of radiation oncology, biology, physics (01-06-2007)“…Purpose: To assess prognostic factors for adults with medulloblastoma in a multicenter, retrospective study. Methods and Materials: Data were collected by file…”
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Optimize administration protocol of capecitabine plus docetaxel combination in metastatic breast cancer patients
Published in Current topics in medicinal chemistry (01-08-2012)“…Combining several cytotoxics is the current mainstay for treating breast cancer patients. The combination between capecitabine and docetaxel was found to be…”
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Early severe toxicities after capecitabine intake: possible implication of a cytidine deaminase extensive metabolizer profile
Published in Cancer chemotherapy and pharmacology (01-05-2009)“…We report here the case of a 19-year-old female patient who suffered from extremely severe toxicities (G4 mucitis, fever, diarrhea, alteration of general…”
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Integrating pharmacogenetics into gemcitabine dosing-time for a change?
Published in Nature reviews. Clinical oncology (01-07-2011)“…A number of biomarkers that predict clinical outcome in response to gemcitabine treatment have been identified. These markers could be used in the clinic to…”
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Cytidine Deaminase Residual Activity in Serum Is a Predictive Marker of Early Severe Toxicities in Adults After Gemcitabine-Based Chemotherapies
Published in Journal of clinical oncology (01-01-2010)“…PURPOSE Anticipating toxicities with gemcitabine is an ongoing story, and deregulation in cytidine deaminase (CDA) could be associated with increased risk of…”
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Physicochemical properties and cellular toxicity of (poly)aminoalkoxysilanes-functionalized ZnO quantum dots
Published in Nanotechnology (24-08-2012)“…Luminescent ZnO nanocrystals were synthesized by basic hydrolysis of Zn(OAc)(2) in the presence of oleic acid and then functionalized with…”
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Routine Dihydropyrimidine Dehydrogenase Testing for Anticipating 5-Fluorouracil–Related Severe Toxicities: Hype or Hope?
Published in Clinical colorectal cancer (01-10-2010)“…Abstract 5-Fluorouracil (5-FU) is a mainstay for treating colorectal cancer, alone or more frequently as part of combination therapies. However, its…”
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Severe or lethal toxicities upon capecitabine intake: is DPYD genetic polymorphism the ideal culprit?
Published in Trends in pharmacological sciences (Regular ed.) (01-12-2007)Get full text
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Could daratumumab induce the maturation of plasmablasts in Plasmablastic lymphoma?—Potential therapeutic applications
Published in European journal of haematology (01-04-2021)Get full text
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Pulmonary hypertension in patients with myeloproliferative neoplasms: A large cohort of 183 patients
Published in European journal of internal medicine (01-10-2019)“…Chronic myeloproliferative neoplasms (MPN) are recognized as a cause of pulmonary hypertension (pH). We ought to describe the prevalence and characteristics of…”
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Profiling Dihydropyrimidine Dehydrogenase Deficiency in Patients with Cancer Undergoing 5-Fluorouracil/Capecitabine Therapy
Published in Clinical colorectal cancer (01-11-2006)“…Fluoropyrimidine drugs such as 5-fluorouracil (5-FU) and capecitabine are a mainstay in the treatment of numerous solid tumors, including colorectal cancers,…”
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Efficacy and safety of autologous stem cell transplantation after induction therapy with lenalidomide, bortezomib, and dexamethasone
Published in European journal of haematology (01-10-2019)“…Objectives Recently, phase III trials assessed a new combination of lenalidomide, bortezomib, and dexamethasone (RVD) in induction therapy in…”
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A transcriptomic signature predicting septic outcome in patients undergoing autologous stem cell transplantation
Published in Experimental hematology (01-09-2018)“…•A transcriptomic signature predicts infection in neutropenic patients.•The expression of 11 genes can be used routinely for sepsis prediction.•Early…”
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5-FU-induced neurotoxicity in cancer patients with profound DPD deficiency syndrome: a report of two cases
Published in Cancer chemotherapy and pharmacology (01-09-2011)“…Purpose 5-Fluorouracil (5-FU) is a mainstay for treating various solid tumours in adults, including digestive and head and neck cancers. 5-FU-related…”
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Pulmonary hypertension in patients with chronic myeloproliferative neoplasms
Published in Leukemia & lymphoma (01-01-2014)Get full text
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DPD-based adaptive dosing of 5-FU in patients with head and neck cancer: impact on treatment efficacy and toxicity
Published in Cancer chemotherapy and pharmacology (2011)“…Background Fluoropyrimidine drugs are widely used in head and neck cancer (HNC). DPD deficiency is a pharmacogenetics syndrome associated with severe/lethal…”
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Sudden death related to toxicity in a patient on capecitabine and irinotecan plus bevacizumab intake: pharmacogenetic implications
Published in Journal of clinical oncology (01-02-2012)Get full text
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Genotype-based methods for anticipating gemcitabine-related severe toxicities may lead to false-negative results
Published in Journal of clinical oncology (20-10-2007)Get full text
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