Search Results - "Merchant, Randall"

Effect of Citicoline on Functional and Cognitive Status Among Patients With Traumatic Brain Injury: Citicoline Brain Injury Treatment Trial (COBRIT) by Zafonte, Ross D, Bagiella, Emilia, Ansel, Beth M, Novack, Thomas A, Friedewald, William T, Hesdorffer, Dale C, Timmons, Shelly D, Jallo, Jack, Eisenberg, Howard, Hart, Tessa, Ricker, Joseph H, Diaz-Arrastia, Ramon, Merchant, Randall E, Temkin, Nancy R, Melton, Sherry, Dikmen, Sureyya S

“…CONTEXT Traumatic brain injury (TBI) is a serious public health problem in the United States, yet no treatment is currently available to improve outcome after…”
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Using Decision Tree Methodology to Predict Employment After Moderate to Severe Traumatic Brain Injury by Stromberg, Katharine A, Agyemang, Amma A, Graham, Kristin M, Walker, William C, Sima, Adam P, Marwitz, Jennifer H, Harrison-Felix, Cynthia, Hoffman, Jeanne M, Brown, Allen W, Kreutzer, Jeffrey S, Merchant, Randall

“…To build decision tree prediction models for long-term employment outcomes of individuals after moderate to severe closed traumatic brain injury (TBI) and…”
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Altered white matter in cocaine-dependent subjects with traumatic brain injury: A diffusion tensor imaging study by Ma, Liangsuo, Steinberg, Joel L, Keyser-Marcus, Lori, Ramesh, Divya, Narayana, Ponnada A, Merchant, Randall E, Moeller, F. Gerard, Cifu, David X

“…Highlights • We tested white matter impairment in cocaine-dependent subjects (CDs). • We conducted diffusion tensor imaging Tract-Based Spatial Statistics…”
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The effect of oral care on intracranial pressure in critically ill adults by Szabo, Christina M, Grap, Mary Jo, Munro, Cindy L, Starkweather, Angela, Merchant, Randall E

“…A major goal in the care of patients with neurological problems is to prevent or minimize episodes of increased intracranial pressure (ICP). Elevations in ICP…”
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Nutritional Supplementation with Chlorella pyrenoidosa Lowers Serum Methylmalonic Acid in Vegans and Vegetarians with a Suspected Vitamin B₁₂ Deficiency by Merchant, Randall Edward, Phillips, Todd W, Udani, Jay

“…Since vitamin B12 occurs in substantial amounts only in foods derived from animals, vegetarians and particularly vegans are at risk of developing deficiencies…”
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Tumor infiltration by myeloid suppressor cells in response to T cell activation in rat gliomas by GRAF, Martin R, SAUER, Jeremy T, MERCHANT, Randall E

“…We have recently reported that activation of tumor-specific T cells by subcutaneous vaccination with irradiated T9 glioma cells of syngeneic rats with a…”
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Molecular detection of tumor-associated antigens shared by human cutaneous melanomas and gliomas by Chi, DD, Merchant, RE, Rand, R, Conrad, AJ, Garrison, D, Turner, R, Morton, DL, Hoon, DS

“…Both melanocytes and glial cells are derived embryologically from the neural ectoderm. Their malignant transformed counterparts, melanoma and glioma cells,…”
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IL-6 Secretion by a Rat T9 Glioma Clone Induces a Neutrophil-Dependent Antitumor Response with Resultant Cellular, Antiglioma Immunity by Graf, Martin R, Prins, Robert M, Merchant, Randall E

“…Previously, we reported that IL-6 transduction attenuates tumor formation of a rat T9 glioma clone (termed T9.F). This study focuses on the mechanisms of the…”
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Thymic function and output of recent thymic emigrant T cells during intracranial glioma progression by Prins, Robert M, Graf, Martin R, Merchant, Randall E, Black, Keith L, Wheeler, Christopher J

“…One of the hallmarks of patients with glioblastoma multiforme (GBM) is profound lymphopenia mostly confined to the T cell lineage. A deficiency in the…”
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Cytotoxic T cells infiltrating a glioma express an aberrant phenotype that is associated with decreased function and apoptosis by PRINS, Robert M, GRAF, Martin R, MERCHANT, Randall E

“…In this study, we report on novel alterations found in rat intracranial (i.c.) tumor-infiltrating T lymphocytes (TIL) that are indicative of T cell defects and…”
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Outcome measures for clinical trials in neurotrauma by Bullock, M Ross, Merchant, Randall E, Choi, Sung C, Gilman, Charlotte B, Kreutzer, Jeffrey S, Marmarou, Anthony, Teasdale, Graham M

“…Under the auspices of the American Brain Injury Consortium and the Joint Section of Neurotrauma and Critical Care of the American Association of Neurological…”
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Nutritional supplementation with Chlorella pyrenoidosa for mild to moderate hypertension by Merchant, Randall E, Andre, Cynthia A, Sica, Domenic A

“…Pharmacological treatment of hypertension reduces the risk of cardiovascular disease; however, randomized, controlled clinical trials and population studies…”
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Irradiated tumor cell vaccine for treatment of an established glioma. II. Expansion of myeloid suppressor cells that promote tumor progression by PRINS, Robert M, SCOTT, Gail P, MERCHANT, Randall E, GRAF, Martin R

“…These studies report the identification of a population of myeloid suppressor cells (MSC) that are preferentially enriched in the spleens and…”
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Diagnosing Level of Consciousness: The Limits of the Glasgow Coma Scale Total Score by Bodien, Yelena G, Barra, Alice, Temkin, Nancy R, Barber, Jason, Foreman, Brandon, Vassar, Mary, Robertson, Claudia, Taylor, Sabrina R, Markowitz, Amy J, Manley, Geoffrey T, Giacino, Joseph T, Edlow, Brian L

“…In nearly all clinical and research contexts, the initial severity of a traumatic brain injury (TBI) is measured using the Glasgow Coma Scale (GCS) total…”
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Prognostic value of day-of-injury plasma GFAP and UCH-L1 concentrations for predicting functional recovery after traumatic brain injury in patients from the US TRACK-TBI cohort: an observational cohort study by Korley, Frederick K, Jain, Sonia, Sun, Xiaoying, Puccio, Ava M, Yue, John K, Gardner, Raquel C, Wang, Kevin K W, Okonkwo, David O, Yuh, Esther L, Mukherjee, Pratik, Nelson, Lindsay D, Taylor, Sabrina R, Markowitz, Amy J, Diaz-Arrastia, Ramon, Manley, Geoffrey T, Adeoye, Opeolu, Badatjia, Neeraj, Duhaime, Ann-Christine, Ferguson, Adam, Foreman, Brandon, Giacino, Joseph T, Gopinath, Shankar, Grandhi, Ramesh, Kitagawa, Ryan, Madden, Christopher, Merchant, Randall, McCrea, Mike, Ngwenya, Laura, Rabinowitz, Miri, Robertson, Claudia, Schnyer, David, Stein, Murray, Vassar, Mary, Wang, Vincent, Valadka, Alex, Zafonte, Ross

“…The prognostic value of glial fibrillary acidic protein (GFAP) and ubiquitin C-terminal hydrolase L1 (UCH-L1) as day-of-injury predictors of functional outcome…”
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Irradiated tumor cell vaccine for treatment of an established glioma. I. Successful treatment with combined radiotherapy and cellular vaccination by GRAF, Martin R, PRINS, Robert M, HAWKINS, William T, MERCHANT, Randall E

“…Rats bearing a 5-day intracranial (i.c.) syngeneic glioma were treated with a subcutaneous (s.c.) vaccination consisting of irradiated glioma cells or a…”
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Predicting Long-Term Global Outcome after Traumatic Brain Injury: Development of a Practical Prognostic Tool Using the Traumatic Brain Injury Model Systems National Database by Walker, William C, Stromberg, Katharine A, Marwitz, Jennifer H, Sima, Adam P, Agyemang, Amma A, Graham, Kristin M, Harrison-Felix, Cynthia, Hoffman, Jeanne M, Brown, Allen W, Kreutzer, Jeffrey S, Merchant, Randall

“…For patients surviving serious traumatic brain injury (TBI), families and other stakeholders often desire information on long-term functional prognosis, but…”
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Cognitive Outcome 1 Year After Mild Traumatic Brain Injury: Results From the TRACK-TBI Study by Schneider, Andrea L.C., Huie, J. Russell, Boscardin, W. John, Nelson, Lindsay, Barber, Jason K., Yaffe, Kristine, Diaz-Arrastia, Ramon, Ferguson, Adam R., Kramer, Joel, Jain, Sonia, Temkin, Nancy, Yuh, Esther, Manley, Geoffrey T., Gardner, Raquel C.

“…The objectives of this study were to develop and establish concurrent validity of a clinically relevant definition of poor cognitive outcome 1 year after mild…”
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Association of obesity with mild traumatic brain injury symptoms, inflammatory profile, quality of life and functional outcomes: a TRACK-TBI Study by Eagle, Shawn R, Puccio, Ava M, Nelson, Lindsay D, McCrea, Michael, Giacino, Joseph, Diaz-Arrastia, Ramon, Conkright, William, Jain, Sonia, Sun, Xiaoying, Manley, Geoffrey, Okonkwo, David O, Ferguson, Adam R., Gopinath, Shankar, Grandhi, Ramesh, Dirk Keene, C., Merchant, Randall, Robertson, Claudia, Schnyer, David, Temkin, Nancy, Yue, John K., Zafonte, Ross

“…AbstractObjectivesObesity is associated with chronic inflammation, which may impact recovery from mild traumatic brain injury (mTBI). The objective was to…”
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Contrasting effects of interleukin-2 secretion by rat glioma cells contingent upon anatomical location: accelerated tumorigenesis in the central nervous system and complete rejection in the periphery by Graf, Martin R, Prins, Robert M, Poulsen, Gail A, Merchant, Randall E

“…Rat T9.F glioma cells were transduced with the interleukin (IL)-2 gene. Clone T9.F/IL2/#12 secreted a high level of IL-2 (15 ng/10 6 cells/48 h). Enhanced…”
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