Search Results - "Mercer, A.A"

Vascular endothelial growth factor (VEGF)-like protein from orf virus NZ2 binds to VEGFR2 and neuropilin-1 by Wise, L.M, Veikkola, T, Mercer, A.A, Savory, L.J, Fleming, S.B, Caesar, C, Vitali, A, Makinen, T, Alitalo, K, Stacker, S.A

“…Orf virus, a member of the poxvirus family, produces a pustular dermatitis in sheep, goats, and humans. The lesions induced after infection with orf virus show…”
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Infection with recombinant orf viruses demonstrates that the viral interleukin-10 is a virulence factor by Fleming, S.B, Anderson, I.E, Thomson, J, Deane, D.L, McInnes, C.J, McCaughan, C.A, Mercer, A.A, Haig, D.M

“…Orf virus is the prototype parapoxvirus that causes the contagious skin disease orf. It encodes an orthologue of the cytokine interleukin (IL)-10. Recombinant…”
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Bovine papular stomatitis virus encodes a functionally distinct VEGF that binds both VEGFR-1 and VEGFR-2 by Inder, M.K, Ueda, N, Mercer, A.A, Fleming, S.B, Wise, L.M

“…Bovine papular stomatitis virus (BPSV), a member of the genus Parapoxvirus, causes proliferative dermatitis in cattle and humans. Other species of the genus…”
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Orf virus interleukin-10 inhibits cytokine synthesis in activated human THP-1 monocytes, but only partially impairs their proliferation by Wise, L, McCaughan, C, Tan, C.K, Mercer, A.A, Fleming, S.B

“…The sheep parapoxvirus orf virus (ORFV) induces acute, pustular skin lesions in humans. ORFV encodes an orthologue of interleukin-10 (IL-10) that, whilst it…”
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Recent isolates of parapoxvirus of Finnish reindeer (Rangifer tarandus tarandus) are closely related to bovine Pseudocowpox virus by Tikkanen, M.K, McInnes, C.J, Mercer, A.A, Buttner, M, Tuimala, J, Hirvela-Koski, V, Neuvonen, E, Huovilainen, A

“…1 National Veterinary and Food Research Institute, Department of Virology, PO Box 45, Hämeentie 57, FIN-00581 Helsinki, Finland 2 Moredun Research Institute,…”
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A homolog of interleukin-10 is encoded by the poxvirus orf virus by Fleming, S.B. (University of Otago, Dunedin, New Zealand.), McCaughan, C.A, Andrews, A.E, Nash, A.D, Mercer, A.A

“…A gene encoding a polypeptide with homology to interleukin-10 (IL-10) has been discovered in the genome of orf virus (OV) strain NZ2, a parapoxvirus that…”
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Vascular endothelial growth factors encoded by Orf virus show surprising sequence variation but have a conserved, functionally relevant structure by Mercer, A.A, Wise, L.M, Scagliarini, A, McInnes, C.J, Buttner, M, Rziha, H.J, McCaughan, C.A, Fleming, S.B, Ueda, N, Nettleton, P.F

“…The first report of a vascular endothelial growth factor (VEGF)-like gene in Orf virus included the surprising observation that the genes from two isolates…”
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Homologs of vascular endothelial growth factor are encoded by the Poxvirus orf virus by LYTTLE, D. J, FRASER, K. M, FLEMING, S. B, MERCER, A. A, ROBINSON, A. J

“…A gene encoding a polypeptide with homology to mammalian vascular endothelial growth factors (VEGFs) has been discovered in the genome of orf virus (OV), a…”
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Parapoxviruses are strongly inhibited in vitro by cidofovir by Nettleton, P.F, Gilray, J.A, Reid, H.W, Mercer, A.A

“…Three parapoxviruses which cause orf or related diseases in humans and animals and the orthopoxvirus, vaccinia virus, were tested for their in vitro…”
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Parapoxvirus of Red Deer: Evidence for Its Inclusion as a New Member in the Genus Parapoxvirus by Robinson, Anthony J., Mercer, Andrew A.

“…There are three accepted members of the parapoxvirus genus, orf virus (OV), papular stomatitis virus (PSV), and pseudocowpox virus (PCV). OV is maintained in…”
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Molecular characterization of a plasmid-borne (pGT633) erythromycin resistance determinant (ermGT) from Lactobacillus reuteri 100-63 by Tannock, G W, Luchansky, J B, Miller, L, Connell, H, Thode-Andersen, S, Mercer, A A, Klaenhammer, T R

“…Lactobacillus reuteri 100-63 contains a 9.8 kb plasmid (pGT633) encoding resistance to the macrolide-lincosamide-streptogramin (MLS) type B antibiotics. The…”
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reactivity of monoclonal antibodies against orf virus with other parapoxviruses and the identification of a 39 kDa immunodominant protein by Housawi, F.M.T, Roberts, G.M, Gilray, J.A, Pow, I, Reid, H.W, Nettleton, P.F, Sumption, K.J, Hibma, M.H, Mercer, A.A

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Lack of cross-protection between vaccinia virus and orf virus in hysterectomy-procured, barrier-maintained lambs by Mercer, A A, Yirrell, D L, Reid, H W, Robinson, A J

“…Hysterectomy-procured, barrier maintained lambs were immunised with either of virus or vaccinia virus and subsequently challenged with both viruses. Under…”
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The structure and cloning of orf virus DNA by Mercer, A A, Fraser, K, Barns, G, Robinson, A J

“…A map of cleavage sites for the restriction endonucleases EcoRI, HindIII, BamHI, HpaI, and KpnI for a New Zealand strain of orf virus (NZ2) DNA has been…”
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Sequence and transcriptional analysis of an orf virus gene encoding ankyrinlike repeat sequences by Sullivan, J.T. (Otago Univ., Dunedin (New Zealand). Centre for Gene Research), Fraser, K.M, Fleming, S.B, Robinson, A.J, Mercer, A.A

“…A 1608 bp region located approximately 5.0 kb from the left end of the orf virus (OV) genome (strain NZ2) was sequenced. The sequence revealed a single open…”
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Vaccinia virus-like early transcriptional control sequences flank an early gene in orf virus by Fleming, S B, Fraser, K M, Mercer, A A, Robinson, A J

“…The purpose of this study was to map the initiation (tsp) and termination points of transcripts arising from an open reading frame (ORF3) found in the inverted…”
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orf virus sequence showing homology to the 14K 'fusion' protein of vaccinia virus by Naase, M, Nicholson, B.H, Fraser, K.M, Mercer, A.A, Robinson, A.J

“…The nucleotide sequence of a region of DNA 30 kb from the right end of the orf virus genome has been determined. Examination of the sequences revealed an open…”
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Conservation and variation in orf virus genomes by Robinson, A J, Barns, G, Fraser, K, Carpenter, E, Mercer, A A

“…The genomes of several orf virus strains were analyzed with the restriction endonucleases EcoRI, HindIII, BamHI, and KpnI, and cleavage site maps were deduced…”
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Orf virus and vaccinia virus do not cross-protect sheep by Robinson, A.J, Mercer, A.A

“…Inoculation of lambs with a New Zealand strain of orf virus (NZ 2) failed to protect them against subsequent infection with the Lister strain of vaccinia…”
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