Search Results - "Mercep, Mladen"

Inactivation of S6 ribosomal protein gene in T lymphocytes activates a p53-dependent checkpoint response by Sulic, Sanda, Panic, Linda, Barkic, Martina, Mercep, Mladen, Uzelac, Miljana, Volarevic, Sinisa

“…Ribosome biogenesis has been associated with regulation of cell growth and cell division, but the molecular mechanisms that integrate the effect of ribosome…”
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Macrolactonolides: A novel class of anti-inflammatory compounds by Tomašković, Linda, Komac, Marijana, Makaruha Stegić, Oresta, Munić, Vesna, Ralić, Jovica, Stanić, Barbara, Banjanac, Mihailo, Marković, Stribor, Hrvačić, Boška, Čipčić Paljetak, Hana, Padovan, Jasna, Glojnarić, Ines, Eraković Haber, Vesna, Mesić, Milan, Merćep, Mladen

“…A new concept in design of safe glucocorticoid therapy was introduced by conjugating potent glucocorticoid steroids with macrolides (macrolactonolides). These…”
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Specific detection of protein carbonylation sites by 473 nm photodissociation mass spectrometry by Ladouce, Romain, MacAleese, Luke, Wittine, Karlo, Merćep, Mladen, Girod, Marion

“…The study of protein oxidation remains a challenge despite the biomedical interest in reliable biomarkers of oxidative stress. This is particularly true for…”
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Applicability of an ultrasonic nebulization system for the airways delivery of beclomethasone dipropionate in a murine model of asthma by HRVACIE, Boska, BOSNJAK, Berislav, TUDJA, Marijan, MESIE, Milan, MERCEP, Mladen

“…We have assessed the use of an ultrasonic nebulization system (UNS), composed of ultrasonic nebulizer and diffusion dryer filled with charcoal, for the…”
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2,8-Dithia-dibenzo[e,h]azulenes and Their 8-Oxa Analogs. Synthesis and Anti-inflammatory Activity by Ozimec Landek, Ivana, Pešić, Dijana, Novak, Predrag, Stanić, Barbara, Nujić, Krunoslav, Merćep, Mladen, Mesić, Milan

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Oxime blot: A novel method for reliable and sensitive detection of carbonylated proteins in diverse biological systems by Ladouce, Romain, Combes, Guillaume Fabien, Trajković, Katarina, Drmić Hofman, Irena, Merćep, Mladen

“…Oxidative stress and oxidative protein damage occur in various biological processes and diseases. The carbonyl group on amino acid side chains is the most…”
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Synthesis of 2-formyl-1-aza-dibenzo[e,h]azulenes by Pešić, Dijana, Landek, Ivana Ozimec, Čikoš, Ana, Metelko, Biserka, Gabelica, Vesna, Stanić, Barbara, Merćep, Mladen, Mesić, Milan

“…Synthesis of a novel heterocyclic class of compounds, 1‐aza‐dibenzo[e,h]azulenes [1] (6a‐c and 7a‐c), derived from dibenzo[b,f]oxepin, its 8‐chloro analogue…”
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Structural mutations of the T cell receptor ζ chain and its role in T cell activation by FRANK, S. J, NIKLINSKA, B. B, ORLOFF, D. G, MERCEP, M, ASHWELL, J. D, KLAUSNER, R. D

“…T cell hybridomas that express zeta zeta, but not zeta eta, dimers in their T cell receptors (TCRs) produce interleukin-2 (IL-2) and undergo an inhibition of…”
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Activation-Driven Programmed Cell Death and T Cell Receptor $\zeta \eta $ Expression by Merćep, Mladen, Weissman, Allan M., Frank, Stuart J., Klausner, Richard D., Ashwell, Jonathan D.

“…Activation of spontaneously dividing T cell hybridomas induces interleukin-2 (IL-2) production, a cell cycle block, and programmed cell death. T cell…”
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Dibenzo[b,f]oxepin-10(11H)-one and dibenzo[b,f]thiepin-10(11H)-one as useful synthons in the synthesis of various dibenzo[e,h]azulenes by Pešić, Dijana, Landek, Ivana Ozimec, Rupčić, Renata, Modrić, Marina, Džapo, Iva, Trojko, Rudolf, Merćep, Mladen, Mesić, Milan

“…The present review focuses on dibenzo[b,f]oxepin‐10(11H)‐one (I, X = O) and dibenzo[b,f]thiepin‐10(11H)‐one (I, X = S) as common synthons in the efficient…”
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Bone morphogenetic protein (BMP)1-3 enhances bone repair by Grgurevic, Lovorka, Macek, Boris, Mercep, Mladen, Jelic, Mislav, Smoljanovic, Tomislav, Erjavec, Igor, Dumic-Cule, Ivo, Prgomet, Stefan, Durdevic, Dragan, Vnuk, Drazen, Lipar, Marija, Stejskal, Marko, Kufner, Vera, Brkljacic, Jelena, Maticic, Drazen, Vukicevic, Slobodan

“…►BMP1-3 isoform circulates in the human plasma. ► BMP1-3 has an important role in bone repair. ► BMP1-3 as a novel biomarker of bone regeneration. ► BMP1-3…”
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Novel tetracyclic imidazole derivatives: Synthesis, dynamic NMR study, and anti-inflammatory evaluation by Rupčić, Renata, Modrić, Marina, Hutinec, Antun, Čikoš, Ana, Stanić, Barbara, Mesić, Milan, Pešić, Dijana, Merćep, Mladen

“…A series of tetracyclic imidazole derivatives 9a, 9b, 9c, 9d, 9e, 9f, 9g, 9h, 9i, 9j, 9k, 9l, 9m, 9n, 9o, 9p, 9r, 9s, 9t, 9v and 10a, 10b, 10c, 10d, 10e, 10f,…”
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Synthesis and anti-inflammatory activity of 8H-1-thia-8-aza-dibenzo[e,h]azulenes by Ozimec Landek, Ivana, Pešić, Dijana, Merćep, Mladen, Stanić, Barbara, Mesić, Milan

“…Synthesis of a novel class of fused heterotetracyclic compounds, 8H‐1‐thia‐8‐aza‐dibenzo[e,h]azulenes (VII), is described. Starting N‐benzoyl‐protected…”
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Synthesis of Naphtho[2,3-b]- and Naphtho[1,2-b]-fused Thieno[2,3-d][1]benzoxepins and Thieno[2,3-d][1]benzothiepins by Ozimec Landek, Ivana, Pešić, Dijana, Trojko, Rudolf, Devčić Bogdanović, Maja, Merćep, Mladen

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Dominant Negative Variants of the SHP-2 Tyrosine Phosphatase Inhibit Prolactin Activation of Jak2 (Janus Kinase 2) and Induction of Stat5 (Signal Transducer and Activator of Transcription 5)-Dependent Transcription by Berchtold, Susanne, Volarevic, Sinisa, Moriggl, Richard, Mercep, Mladen, Groner, Bernd

“…PRL plays a central role in the regulation of milk protein gene expression in mammary epithelial cells and in the growth and differentiation of lymphocytes. It…”
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Dissociation of Phosphoinositide Hydrolysis and Ca(2plus) Fluxes from the Biological Responses of a T-Cell Hybridoma by Sussman, Jeffrey J, Mercep, Mladen, Saito, Takashi, Germain, Ronald N, Bonvini, Ezio

“…T lymphocytes can be activated in a variety of ways, including occupancy of the T cell antigen receptor (TCR) complex or cross-linking of certain cell-surface…”
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T cell CD3-zeta eta heterodimer expression and coupling to phosphoinositide hydrolysis by Merćep, M, Bonifacino, J S, Garcia-Morales, P, Samelson, L E, Klausner, R D, Ashwell, J D

“…The T cell antigen receptor consists of an antigen-binding heterodimer that is noncovalently associated with at least five CD3 subunits (gamma, delta, epsilon,…”
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Synthesis and anti‐inflammatory activity of 8 H ‐1‐thia‐8‐aza‐dibenzo[ e , h ]azulenes by Ozimec Landek, Ivana, Pešić, Dijana, Merćep, Mladen, Stanić, Barbara, Mesić, Milan

“…Synthesis of a novel class of fused heterotetracyclic compounds, 8 H ‐1‐thia‐8‐aza‐dibenzo[ e , h ]azulenes ( VII ), is described. Starting N…”
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Fas and activation-induced Fas ligand mediate apoptosis of T cell hybridomas: inhibition of Fas ligand expression by retinoic acid and glucocorticoids by Yang, Y, Merćep, M, Ware, C F, Ashwell, J D

“…Activation of T cell hybridomas induces a G1/S cell cycle block and apoptosis. We isolated a variant of the 2B4.11 T cell hybridoma that, when activated via…”
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Activation-Driven Programmed Cell Death and T Cell Receptor Expression by Frank, Stuart J, Weissman, Allan M, Mercep, Mladen, Ashwell, Jonathan D, Klausner, Richard D

“…T cell hybidomas that express the T cell antigen receptor homodimer, but not the TCR heterodimer, are examined…”
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