Search Results - "Mera, Elvia"
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1
Role of pregnancy on insulin-induced vasorelaxation: the influence of angiotensin II receptors
Published in Canadian journal of physiology and pharmacology (01-10-2021)“…Insulin resistance is a feature of pregnancy and is associated with increased levels of angiotensin II (Ang II) and insulin. Therefore, pregnancy may change…”
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2
Dihydroergotamine Increases Histamine Brain Levels and Improves Memory in a Scopolamine-Induced Amnesia Model
Published in International journal of molecular sciences (01-04-2024)“…The beneficial effects of increasing histamine levels on memory have acquired special interest due to their applicability to psychiatric conditions that cause…”
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3
Computational Studies of Aflatoxin B1 (AFB1): A Review
Published in Toxins (07-02-2023)“…Aflatoxin B1 (AFB1) exhibits the most potent mutagenic and carcinogenic activity among aflatoxins. For this reason, AFB1 is recognized as a human group 1…”
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4
Drug Repurposing to Inhibit Histamine N -Methyl Transferase
Published in Molecules (Basel, Switzerland) (06-01-2023)“…Lower activity of the histaminergic system is associated with neurological disorders, including Alzheimer's disease (AD). Thus, the enhancement of…”
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5
Epigallocatechin 3-Gallate Has a Neuroprotective Effect in Retinas of Rabbits with Ischemia/Reperfusion through the Activation of Nrf2/HO-1
Published in International journal of molecular sciences (25-05-2020)“…Retinal ischemia-reperfusion (rI/R) generates an oxidative condition causing the death of neuronal cells. Epigallocatechin 3-gallate (EGCG) has antioxidant and…”
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6
In Vitro and Computational Studies of Perezone and Perezone Angelate as Potential Anti-Glioblastoma Multiforme Agents
Published in Molecules (Basel, Switzerland) (26-02-2022)“…Glioblastoma multiforme (GBM) represents the most malignant type of astrocytoma, with a life expectancy of two years. It has been shown that Poly (ADP-ribose)…”
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Inhibition of Astrocytic Histamine N -Methyltransferase as a Possible Target for the Treatment of Alzheimer's Disease
Published in Biomolecules (Basel, Switzerland) (26-09-2021)“…Alzheimer's disease (AD) represents the principal cause of dementia among the elderly. Great efforts have been established to understand the physiopathology of…”
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Synthesis, Cytotoxic Activity and In Silico Study of Novel Dihydropyridine Carboxylic Acids Derivatives
Published in International journal of molecular sciences (01-10-2023)“…To aid the possible prevention of multidrug resistance in tumors and cause lower toxicity, a set of sixteen novel dihydropyridine carboxylic acids derivatives…”
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9
Design of Two New Sulfur Derivatives of Perezone: In Silico Study Simulation Targeting PARP-1 and In Vitro Study Validation Using Cancer Cell Lines
Published in International journal of molecular sciences (01-01-2024)“…Poly-ADP-Ribose Polymerase (PARP-1) is an overexpressed enzyme in several carcinomas; consequently, the design of PARP-1 inhibitors has acquired special…”
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10
Synthesis of New Isoindolines Derived from L‐Α‐Amino Acids and their Selectivity on Cancer Cell Lines
Published in ChemistrySelect (Weinheim) (26-01-2024)“…Isoindolines are essential from the point of view of synthesis and their biological properties, so this work is focused on the synthesis of new isoindolines…”
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11
In vitro and computational studies of natural products related to perezone as anti-neoplastic agents
Published in Biochimie (01-04-2020)“…Many natural phyto-products as perezone (Per) exhibit anti-cancer activities. Using experimental and computational studies, it was described that Poly…”
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12
Compliance With Biochemical Objectives in Patients on Renal Replacement Therapy Before Kidney Transplantation in Mexico
Published in Transplantation proceedings (01-05-2020)“…The biochemical conditions in which patients arrive before renal transplantation (RT) are rarely evaluated; examples of them are found in the Dialysis Outcomes…”
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13
Complications of Renal Transplantation That Influence the Presence of Hyperuricemia in Its First Year of Evolution
Published in Transplantation proceedings (01-05-2020)“…Renal transplantation (RT) has evolved to improve its functionality. Some factors have been little studied, one of which is hyperuricemia and its impact on…”
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14
Partition coefficient determination of a series of isoindolines-2-substituted and its correlation with their antiproliferative activity on HeLa cells
Published in Medicinal chemistry research (01-08-2013)“…In this study, the partition coefficients (Log P ) of two series of isoindolines-2-substituted were calculated from the equation obtained for the multilinear…”
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15
Synthesis, characterization of novel isoindolinyl- and bis-isoindolinylphenylboronic anhydrides. Antiproliferative activity on glioblastoma cells and microglial cells assays of boron and isoindolines compounds
Published in Journal of organometallic chemistry (01-08-2019)“…Boron compounds importance have been raising due to the development of its synthesis and remarkable biological activities, so in this manner the study here…”
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16
In vitro and computational studies showed that perezone inhibits PARP-1 and induces changes in the redox state of K562 cells
Published in Archives of biochemistry and biophysics (15-08-2019)“…Cancer is one of the leading causes of morbidity and mortality worldwide. This disease is characterized by uncontrolled growth and proliferation of abnormal…”
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17
Participation of COX-1 and COX-2 in the contractile effect of phenylephrine in prepubescent and old rats
Published in The Korean journal of physiology & pharmacology (01-07-2017)“…Vascular reactivity can be influenced by the vascular region, animal age, and pathologies present. Prostaglandins (produced by COX-1 and COX-2) play an…”
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Effect of two series of isoindolines over HDAC8 activity and expression
Published in Medicinal chemistry research (01-06-2014)“…This work describes the effect of two series of isoindolines 1 ( a – g ) and 2 ( a – g ) on histone deacetylase 8 (HDAC8) activity by theoretical study…”
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Anticancer mechanisms determination of N‐(o‐carboxybenzoyl)‐derived compounds of L‐amino acids serie on MDA‐MB‐231 cell line of TNBC
Published in The FASEB journal (01-04-2019)“…Breast cancer is ranked as the second most frequent neoplasm worldwide [1], of which approximately 15% is subclassified as triple negative breast cancer…”
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Anticancer mechanisms determination of L‐aminoacids compounds serie on MDA‐MB‐231 cell line TNBC
Published in The FASEB journal (01-04-2020)“…Abstract only…”
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