Search Results - "Mepham, Jennifer"

The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders by Thomas, Raymond H, Meeking, Melissa M, Mepham, Jennifer R, Tichenoff, Lisa, Possmayer, Fred, Liu, Suya, MacFabe, Derrick F

“…Gastrointestinal symptoms and altered blood phospholipid profiles have been reported in patients with autism spectrum disorders (ASD). Most of the phospholipid…”
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Propionic acid induced behavioural effects of relevance to autism spectrum disorder evaluated in the hole board test with rats by Meeking, Melissa M., MacFabe, Derrick F., Mepham, Jennifer R., Foley, Kelly A., Tichenoff, Lisa J., Boon, Francis H., Kavaliers, Martin, Ossenkopp, Klaus-Peter

“…Autism spectrum disorders (ASD) are a set of neurodevelopmental disorders characterized by abnormal social interactions, impaired language, and stereotypic and…”
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Examining the non-spatial pretraining effect on a water maze spatial learning task in rats treated with multiple intracerebroventricular (ICV) infusions of propionic acid: Contributions to a rodent model of ASD by Mepham, Jennifer R., MacFabe, Derrick F., Boon, Francis H., Foley, Kelly A., Cain, Donald P., Ossenkopp, Klaus-Peter

“…•ICV infusion of PPA produced hyperactivity (increased distance travelled) in an open-field test in adult male rats.•ICV infusions of PPA produced faster…”
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Altered brain phospholipid and acylcarnitine profiles in propionic acid infused rodents: further development of a potential model of autism spectrum disorders by Thomas, Raymond H, Foley, Kelly A, Mepham, Jennifer R, Tichenoff, Lisa J, Possmayer, Fred, MacFabe, Derrick F

“…J. Neurochem. (2010) 113, 515-529. Recent studies have demonstrated intraventricular infusions of propionic acid (PPA) a dietary and enteric short-chain fatty…”
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Impaired Spatial Cognition in Adult Rats Treated with Multiple Intracerebroventricular (ICV) Infusions of the Enteric Bacterial Metabolite, Propionic Acid, and Return to Baseline After 1 Week of No Treatment: Contribution to a Rodent Model of ASD by Mepham, Jennifer R., Boon, Francis H., Foley, Kelly A., Cain, Donald P., MacFabe, Derrick F., Ossenkopp, Klaus-Peter

“…Propionic acid (PPA) is a dietary short chain fatty acid and an enteric bacterial metabolite. Intracerebroventricular (ICV) infusions of PPA in rodents have…”
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Exploring the effect of prenatal maternal stress on the microbiomes of mothers and infants: A systematic review by Mepham, Jennifer, Nelles‐McGee, Taylor, Andrews, Krysta, Gonzalez, Andrea

“…Prenatal maternal stress (PNMS)—characterized by exposure to stress, anxiety, depression, or intimate partner violence—has been linked to biological…”
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Maternal Childhood Maltreatment History and Child Behavior Problems: Developmental Patterns and Mediation via Maternal Depressive Symptoms and Parenting Behavior by Harris, Madeleine, MacMillan, Harriet, Mepham, Jennifer, Joshi, Divya, Wekerle, Christine, Atkinson, Leslie, Gonzalez, Andrea

“…Maternal exposure to childhood maltreatment (CM) is associated with offspring behavioral problems; however, little work has examined these associations…”
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Cytosolic TDP-43 expression following axotomy is associated with caspase 3 activation in NFL−/− mice: Support for a role for TDP-43 in the physiological response to neuronal injury by Moisse, Katie, Mepham, Jennifer, Volkening, Kathryn, Welch, Ian, Hill, Tracy, Strong, Michael J

“…Abstract TAR DNA binding protein (TDP-43) mislocalization has been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS). We have recently…”
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An investigation of the experiences of physiotherapists during the Aotearoa New Zealand COVID-19 pandemic 2020 by Goh, Pei Han

“…Explores the experiences of physiotherapists in New Zealand during the initial Covid-19 outbreak in early 2020, using an online survey of workers from both the…”
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The complement factor C5a receptor is upregulated in NFL−/− mouse motor neurons by Humayun, Saima, Gohar, May, Volkening, Kathryn, Moisse, Katie, Leystra-Lantz, Cheryl, Mepham, Jennifer, McLean, Jesse, Strong, Michael J

“…Abstract In NFL−/− mice, a model of motor neuron degeneration in ALS, degenerating spinal motor neurons express high levels of the receptor for the C5a…”
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