Search Results - "Meola, Dawn"

Using cultured canine cardiac slices to model the autophagic flux with doxorubicin by Boukhalfa, Asma, Robinson, Sally R, Meola, Dawn M, Robinson, Nicholas A, Ling, Lauren A, LaMastro, Joey N, Upshaw, Jenica N, Pulakat, Lakshmi, Jaffe, Iris Z, London, Cheryl A, Chen, Howard H, Yang, Vicky K

“…Chemotherapy-induced impairment of autophagy is implicated in cardiac toxicity induced by anti-cancer drugs. Imperfect translation from rodent models and lack…”
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Evaluation of matrix metalloproteinases and tissue inhibitors of metalloproteinases in aqueous humor of dogs with versus without naturally occurring primary angle-closure glaucoma by Pumphrey, Stephanie A, Zitek-Morrison, Emily, Pizzirani, Stefano, Meola, Dawn M

“…To compare concentrations of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinases (TIMPs) in aqueous humor from ophthalmologically…”
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Defining the Role of the miR-145-KLF4-αSMA Axis in Mitral Valvular Interstitial Cell Activation in Myxomatous Mitral Valve Prolapse Using the Canine Model by Yang, Vicky K, Moyer, Nicole, Zhou, Runzi, Carnevale, Sally Z, Meola, Dawn M, Robinson, Sally R, Li, Guoping, Das, Saumya

“…Mitral valve prolapse (MVP) is a common valvular disease, affecting 2-3% of the adult human population and is a degenerative condition. A total of 5-10% of the…”
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Extracellular Vesicles from Wharton's Jelly Mesenchymal Stem Cells Suppress CD4 Expressing T Cells Through Transforming Growth Factor Beta and Adenosine Signaling in a Canine Model by Crain, Sarah K, Robinson, Sally R, Thane, Kristen E, Davis, Airiel M, Meola, Dawn M, Barton, Bruce A, Yang, Vicky K, Hoffman, Andrew M

“…Mesenchymal stem cells (MSCs) are widely investigated as potential therapeutic agents due to their potent immunomodulatory capacity. Although specific…”
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Extracellular vesicular microRNAs as potential biomarker for early detection of doxorubicin‐induced cardiotoxicity by Beaumier, Amelie, Robinson, Sally R., Robinson, Nicholas, Lopez, Katherine E., Meola, Dawn M., Barber, Lisa G., Bulmer, Barret J., Calvalido, Jerome, Rush, John E., Yeri, Ashish, Das, Saumya, Yang, Vicky K.

“…Background Long‐term use of doxorubicin (DOX) is limited by cumulative dose‐dependent cardiotoxicity. Objectives Identify plasma extracellular vesicle…”
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Dysregulation of valvular interstitial cell let-7c, miR-17, miR-20a, and miR-30d in naturally occurring canine myxomatous mitral valve disease by Yang, Vicky K, Tai, Albert K, Huh, Terry P, Meola, Dawn M, Juhr, Christine M, Robinson, Nicholas A, Hoffman, Andrew M

“…Canine myxomatous mitral valve disease (MMVD) resembles the early stages of myxomatous pathology seen in human non-syndromic mitral valve prolapse, a common…”
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Intravenous administration of allogeneic Wharton jelly–derived mesenchymal stem cells for treatment of dogs with congestive heart failure secondary to myxomatous mitral valve disease by Yang, Vicky K., Meola, Dawn M., Davis, Airiel, Barton, Bruce, Hoffman, Andrew M.

“…OBJECTIVETo evaluate whether mesenchymal stem cells (MSCs) can be safely administered IV to dogs with congestive heart failure (CHF) secondary to myxomatous…”
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Identifying mitigating strategies for endothelial cell dysfunction and hypertension in response to VEGF receptor inhibitors by Camarda, Nicholas D, Lu, Qing, Meola, Dawn M, Man, Joshua J, Song, Zeyuan, Travers, Richard J, Lopez, Katherine E, Powers, Sarah N, Papanastasiou, Malvina, DeRuff, Katherine C, Mullahoo, James, Egri, Shawn B, Davison, Desiree, Sebastiani, Paola, Eblen, Scott T, Buchsbaum, Rachel, Huggins, Gordon S, London, Cheryl A, Jaffe, Jacob D, Upshaw, Jenica N, Yang, Vicky K, Jaffe, Iris Z

“…Vascular endothelial growth factor receptor inhibitors (VEGFRis) improve cancer survival but are associated with treatment-limiting hypertension, often…”
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Circulating exosome microRNA associated with heart failure secondary to myxomatous mitral valve disease in a naturally occurring canine model by Yang, Vicky K., Loughran, Kerry A., Meola, Dawn M., Juhr, Christine M., Thane, Kristen E., Davis, Airiel M., Hoffman, Andrew M.

“…Myxomatous mitral valve disease (MMVD) is functionally and histologically identical to mitral valve prolapse (MVP) in humans. Currently, there are no medical…”
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Comparison of the effects of glycerol, dimethyl sulfoxide, and hydroxyethyl starch solutions for cryopreservation of avian red blood cells by Graham, Jennifer E, Meola, Dawn M, Kini, Nisha R, Hoffman, Andrew M

“…To compare effectiveness of glycerol, dimethyl sulfoxide (DMSO), and hydroxyethyl starch (HES) solutions for cryopreservation of avian RBCs. RBCs from 12…”
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An ex vivo evaluation of efficacy of refrigerated canine plasma by Grochowsky, Adam R., Rozanski, Elizabeth A., de Laforcade, Armelle M., Sharp, Claire R., Meola, Dawn M., Schavone, Jessica J., Brooks, Majory B.

“…Objectives To determine thawing times of fresh frozen plasma (FFP), and to evaluate the activity of hemostatic proteins (coagulation factors V, VII, VIII, IX,…”
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Isolation and Mapping of Telomeric Pentanucleotide (TAACC) n Repeats of the Pacific Whiteleg Shrimp, Penaeus vannamei, Using Fluorescence In Situ Hybridization by Alcivar-Warren, Acacia, Meehan-Meola, Dawn, Wang, Yongping, Guo, Ximing, Zhou, Linghua, Xiang, Jianhai, Moss, Shaun, Arce, Steve, Warren, William, Xu, Zhenkang, Bell, Kireina

“…To develop genetic and physical maps for shrimp, accurate information on the actual number of chromosomes and a large number of genetic markers is needed…”
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Abstract 426: Effects of Non-syndromic Mitral Valve Prolapse on Valvular Interstitial Cell Extracellular Vesicle-associated Non-coding RNA in a Spontaneous Canine Disease Model by Meola, Dawn, Robinson, Sally, Yang, Vicky

“…Abstract only Non-syndromic mitral valve prolapse (MVP), or Barlow’s Disease, is a valvular heart disease with a prevalence of 2-3% in the human adult…”
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Abstract 4146686: Carvedilol Exerts Evolutionarily Conserved Cardioprotective Effects via Autophagy Modulation and Energetics Restoration by Boukhalfa, Asma, SHIN, PEI-TSZ, Meola, Dawn, Showers, Annie, Yu, Ada, Upshaw, Jenica, London, Cheryl, Jaffe, Iris, Pulakat, Lakshmi, Yang, Vicky, Chen, Howard

“…Abstract only Carvedilol (CAR) is an FDA-approved adrenergic blocker commonly given to cardiovascular disease patients. Interestingly, CAR also shows…”
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Abstract 414: A Canine Myocardial Slice Model of Doxorubicin Induced Cardiotoxicity to Study Autophagy Modulation and Its Effect on Extracellular Vesicle Associated Mirna by Robinson, Sally R, Robinson, Nicholas A, Boukhalfa, Asma, Meola, Dawn M, Chen, Howard H, Yang, Vicky K

“…Abstract only Dogs with cancer treated with chemotherapy agents such as doxorubicin (DOX) develop cardiovascular toxicity, providing an opportunity to evaluate…”
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Abstract 13538: Impact of Autophagy Modulation on Apoptosis in Chemotherapy-Induced Cardiac Toxicity by Boukhalfa, Asma, Dawn, Meola M, LaMastro, Joey, Robinson, Sally, Meng, Lin, Weng, Sydney, Robinson, Nicholas, Martin, Greg, Sosnovik, David E, Blanton, Robert M, Yang, Vicky, Chen, Howard H

“…BackgroundCardiotoxicity due to chemotherapy remains a challenge. Cardioprotective interventions have not slowed the progression to heart failure…”
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Abstract 1078: A Cross-species Platform And Phosphoproteomics Analysis To Mitigate Vegfri-induced Hypertension And Endothelial Dysfunction by Camarda, Nicholas D, Lu, Qing, Man, Joshua, Martin, Gregory, Travers, Richard J, Lopez, Katherine E, Meola, Dawn M, Powers, Sarah N, Song, Zeyuan, Papanastasiou, Malvina, DeRuff, Katherine, Mullahoo, James, Egri, Shawn, Davison, Desiree, Eblen, Scott, Jaffe, Jacob, Huggins, Gordon, London, Cheryl, Upshaw, Jenica, Yang, Vicky, Jaffe, Iris Z

“…Abstract only Introduction: Vascular endothelial growth factor receptor inhibitors (VEGFRis) are a class of tyrosine kinase inhibitors (TKIs) used to treat…”
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Multicenter investigation of hemostatic dysfunction in 15 dogs with acute pancreatitis by Nielsen, Lindsey, Holm, Jennifer, Rozanski, Elizabeth, Meola, Dawn, Price, Lori Lyn, Laforcade, Armelle

“…Objective To characterize hemostatic profiles in dogs with acute pancreatitis. Design Prospective and observational study. Setting Tertiary referral centers…”
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Effects of in vitro hemodilution with crystalloids, colloids, and plasma on canine whole blood coagulation as determined by kaolin‐activated thromboelastography by Morris, Bari R., deLaforcade, Armelle, Lee, Joyce, Palmisano, Joseph, Meola, Dawn, Rozanski, Elizabeth

“…OBJECTIVE: To investigate the effects of in vitro hemodilution with lactated Ringers solution (LRS), hetastarch (HES), and fresh frozen plasma (FFP) on whole…”
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Isolation of extracellular vesicle-associated small RNA from canine mitral valve interstitial cells using ultracentrifugation and tangential flow filtration with size exclusion chromatography by Yang, Vicky, Meola, Dawn, Thane, Kristen, Hoffman, Andrew

“…Background : Myxomatous mitral valve disease is a highly prevalent canine cardiac disease that can lead to congestive heart failure. Histologic changes in the…”
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