Search Results - "Menzies, Robert I."

Exosomal transmission of functional aquaporin 2 in kidney cortical collecting duct cells by Street, Jonathan M., Birkhoff, Willem, Menzies, Robert I., Webb, David J., Bailey, Matthew A., Dear, James W.

“…Non‐technical summary  Like most cells, those of the kidney release protein and RNA in structures called exosomes. It is possible that the contents of exosomes…”
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Inhibition of the purinergic P2X7 receptor improves renal perfusion in angiotensin-II-infused rats by Menzies, Robert I, Howarth, Amelia R, Unwin, Robert J, Tam, Frederick W K, Mullins, John J, Bailey, Matthew A

“…Chronic activation of the renin-angiotensin system promotes hypertension, renal microvascular dysfunction, tissue hypoxia, and inflammation. Despite similar…”
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P2X7 receptor knockout does not alter renal function or prevent angiotensin II-induced kidney injury in F344 rats by Nespoux, Josselin, Monaghan, Marie-Louise T., Jones, Natalie K., Stewart, Kevin, Denby, Laura, Czopek, Alicja, Mullins, John J., Menzies, Robert I., Baker, Andrew H., Bailey, Matthew A.

“…P2X7 receptors mediate immune and endothelial cell responses to extracellular ATP. Acute pharmacological blockade increases renal blood flow and filtration…”
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Epigenetic modulators link mitochondrial redox homeostasis to cardiac function in a sex-dependent manner by ElBeck, Zaher, Hossain, Mohammad Bakhtiar, Siga, Humam, Oskolkov, Nikolay, Karlsson, Fredrik, Lindgren, Julia, Walentinsson, Anna, Koppenhöfer, Dominique, Jarvis, Rebecca, Bürli, Roland, Jamier, Tanguy, Franssen, Elske, Firth, Mike, Degasperi, Andrea, Bendtsen, Claus, Menzies, Robert I., Streckfuss-Bömeke, Katrin, Kohlhaas, Michael, Nickel, Alexander G., Lund, Lars H., Maack, Christoph, Végvári, Ákos, Betsholtz, Christer

“…While excessive production of reactive oxygen species (ROS) is a characteristic hallmark of numerous diseases, clinical approaches that ameliorate oxidative…”
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Renal disease pathophysiology and treatment: contributions from the rat by Mullins, Linda J, Conway, Bryan R, Menzies, Robert I, Denby, Laura, Mullins, John J

“…The rat has classically been the species of choice for pharmacological studies and disease modeling, providing a source of high-quality physiological data on…”
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Hyperglycemia-induced Renal P2X7 Receptor Activation Enhances Diabetes-related Injury by Menzies, Robert I., Booth, John W.R., Mullins, John J., Bailey, Matthew A., Tam, Frederick W.K., Norman, Jill T., Unwin, Robert J.

“…Diabetes is a leading cause of renal disease. Glomerular mesangial expansion and fibrosis are hallmarks of diabetic nephropathy and this is thought to be…”
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Selecting the right therapeutic target for kidney disease by Buvall, Lisa, Menzies, Robert I., Williams, Julie, Woollard, Kevin J., Kumar, Chanchal, Granqvist, Anna B., Fritsch, Maria, Feliers, Denis, Reznichenko, Anna, Gianni, Davide, Petrovski, Slavé, Bendtsen, Claus, Bohlooly-Y, Mohammad, Haefliger, Carolina, Danielson, Regina Fritsche, Hansen, Pernille B. L.

“…Kidney disease is a complex disease with several different etiologies and underlying associated pathophysiology. This is reflected by the lack of effective…”
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Estimated health and economic impact of using high-dose influenza vaccine on respiratory and circulatory plus respiratory hospitalizations of older adults in Australia by Raina MacIntyre, C., Kevin Yin, J., Felter, Christian, Menzies, Robert I., Thommes, Edward, Largeron, Nathalie, Moa, Aye M., Trent, Mallory, Costantino, Valentina, Choi, Seulki, Alvarez, Fabián P.

“…•High-dose TIV was cost-effective compared to adjuvanted TIV.•High-dose TIV was effective in preventing influenza-associated respiratory hospitalizations in…”
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Estimating Vaccine Coverage from Serial Trivariate Serologic Data in the Presence of Waning Immunity by Wood, James G., Goeyvaerts, Nele, MacIntyre, C. Raina, Menzies, Robert I., McIntyre, Peter B., Hens, Niel

“…INTRODUCTION:Vaccine coverage data are typically collected through vaccine registers and retrospective surveys. Alternatively, cross-sectional serosurveys…”
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Models of strategies for control of rubella and congenital rubella syndrome—A 40 year experience from Australia by Gao, Zhanhai, Wood, James G, Burgess, Margaret A, Menzies, Robert I, McIntyre, Peter B, MacIntyre, C. Raina

“…Highlights ► Impact of rubella vaccination in Australia was assessed using a mathematical model. ► Model outcomes are consistent with the elimination of…”
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Activation of thiazide-sensitive co-transport by angiotensin II in the cyp1a1-Ren2 hypertensive rat by Ashek, Ali, Menzies, Robert I, Mullins, Linda J, Bellamy, Christopher O C, Harmar, Anthony J, Kenyon, Christopher J, Flatman, Peter W, Mullins, John J, Bailey, Matthew A

“…Transgenic rats with inducible expression of the mouse Ren2 gene were used to elucidate mechanisms leading to the development of hypertension and renal injury…”
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Purinergic signaling in kidney disease by Menzies, Robert I, Tam, Frederick W, Unwin, Robert J, Bailey, Matthew A

“…Nucleotides are key subunits for nucleic acids and provide energy for intracellular metabolism. They can also be released from cells to act physiologically as…”
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Transcription controls growth, cell kinetics and cholesterol supply to sustain ACTH responses by Menzies, Robert I, Zhao, Xin, Mullins, Linda J, Mullins, John J, Cairns, Carolynn, Wrobel, Nicola, Dunbar, Donald R, Bailey, Matthew A, Kenyon, Christopher J

“…Chronic ACTH exposure is associated with adrenal hypertrophy and steroidogenesis. The underlying molecular processes in mice have been analysed by microarray,…”
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Targeting the endothelium by combining endothelin-1 antagonism and SGLT-2 inhibition: better together? by Ambery, Phil, Greasley, Peter J, Menzies, Robert I, Brynne, Lena, Kulkarni, Spoorthy, Oscarsson, Jan, Davenport, Anthony P

“…Endothelin A and B receptors, together with sodium-glucose cotransporter-2 (SGLT-2) channels are important targets in improving endothelial function and…”
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Pneumonia in Elderly Australians: Reduction in Presumptive Pneumococcal Hospitalizations but No Change in All-Cause Pneumonia Hospitalizations Following 7-Valent Pneumococcal Conjugate Vaccination by Menzies, Robert I., Jardine, Andrew, McIntyre, Peter B.

“…Background. Studies evaluating long-term trends in hospitalizations coded as pneumonia following introduction of the 7-valent pneumococcal vaccine (PCV7) are…”
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No evidence of increasing Haemophilus influenzae non-b infection in Australian Aboriginal children by Menzies, Robert I., Markey, Peter, Boyd, Rowena, Koehler, Ann P., McIntyre, Peter B.

“…High, or increasing, rates of invasive Haemophilus influenzae (Hi) type a disease have been reported from North American native children from circumpolar…”
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Reduction in Hospitalizations for Pneumonia Associated With the Introduction of a Pneumococcal Conjugate Vaccination Schedule Without a Booster Dose in Australia by JARDINE, Andrew, MENZIES, Robert I, MCINTYRE, Peter B

“…Postmarketing surveillance of heptavalent pneumococcal conjugate vaccine (7vPCV) has shown significant reductions in admissions coded as pneumonia in countries…”
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Vaccine Preventable Diseases and Vaccination Policy for Indigenous Populations by Menzies, Robert I., MPH, Singleton, Rosalyn J., MD, MPH

“…There are many similarities regarding the health status of Indigenous people in the 4 English-speaking developed countries of North America and the Pacific…”
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The sodium glucose co-transporter 2 inhibitor dapagliflozin ameliorates the fluid-retaining effect of the endothelin A receptor antagonist zibotentan by Veenit, Vandana, Heerspink, Hiddo J L, Ahlström, Christine, Greasley, Peter J, Skritic, Stanko, van Zuydam, Natalie, Kohan, Donald E, Hansen, Pernille B L, Menzies, Robert I

“…ABSTRACT Background Endothelin A receptor antagonists (ETARA) slow chronic kidney disease (CKD) progression but their use is limited due to fluid retention and…”
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Vaccine myopia: adult vaccination also needs attention by Menzies, Robert I, Leask, Julie, Royle, Jenny, MacIntyre, C Raina

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