Search Results - "Menz, Anne"
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Diagnostic and prognostic impact of cytokeratin 18 expression in human tumors: a tissue microarray study on 11,952 tumors
Published in Molecular medicine (Cambridge, Mass.) (15-02-2021)“…Cytokeratin 18 (CK18) is an intermediate filament protein of the cytokeratin acidic type I group and is primarily expressed in single-layered or "simple"…”
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Carboxypeptidase A1 (CPA1) Immunohistochemistry Is Highly Sensitive and Specific for Acinar Cell Carcinoma (ACC) of the Pancreas
Published in The American journal of surgical pathology (01-01-2022)“…Carboxypeptidase A1 (CPA1) is a zinc metalloprotease that is produced in pancreatic acinar cells and plays a role in cleaving C-terminal branched-chain and…”
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3
High prevalence of p16 staining in malignant tumors
Published in PloS one (21-07-2022)“…p16 (CDKN2A) is a member of the INK4 class of cell cycle inhibitors, which is often dysregulated in cancer. However, the prevalence of p16 expression in…”
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4
MUC5AC Expression in Various Tumor Types and Nonneoplastic Tissue: A Tissue Microarray Study on 10 399 Tissue Samples
Published in Technology in cancer research & treatment (01-01-2021)“…Background: Mucin 5AC (MUC5AC) belongs to the glycoprotein family of secreted gel-forming mucins and is physiologically expressed in some epithelial cells…”
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CELA3B immunostaining is a highly specific marker for acinar cell carcinoma of the pancreas
Published in PloS one (28-06-2023)“…Chymotrypsin-like elastase family member 3B (CELA3B, elastase-3B) is a pancreatic enzyme with digestive function in the intestine. Since RNA analyses of normal…”
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Cytokeratin 7 and cytokeratin 20 expression in cancer: A tissue microarray study on 15,424 cancers
Published in Experimental and molecular pathology (01-06-2022)“…Combined analysis of cytokeratin 7 (CK7) and cytokeratin 20 (CK20) is often used for assessing the origin of metastatic cancer. To evaluate the diagnostic…”
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KLK7 expression in human tumors: a tissue microarray study on 13,447 tumors
Published in BMC cancer (03-07-2024)“…Kallikrein-related peptidase 7 (KLK7) is a chymotrypsin-like serine protease which is essential for the desquamation of corneocytes and thus plays a pivotal…”
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Cadherin-16 (CDH16) immunohistochemistry: a useful diagnostic tool for renal cell carcinoma and papillary carcinomas of the thyroid
Published in Scientific reports (09-08-2023)“…Cadherin-16 (CDH16) plays a role in the embryonal development in kidney and thyroid. Downregulation of CDH16 RNA was found in papillary carcinomas of the…”
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Mesothelin Expression in Human Tumors: A Tissue Microarray Study on 12,679 Tumors
Published in Biomedicines (07-04-2021)“…Mesothelin (MSLN) represents an attractive molecule for targeted cancer therapies. To identify tumors that might benefit from such therapies, tissue…”
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Trophoblast Cell Surface Antigen 2 (Trop2) Is Expressed in Cases of EBV-Positive Diffuse Large B-Cell Lymphoma Emerging from Angioimmunoblastic T-Cell Lymphoma
Published in Reports (MDPI) (01-06-2024)“…Although trophoblast cell surface antigen 2 (Trop2)-targeting drugs are already approved or under investigation in various solid tumors, the significance of…”
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Prognostic role of proliferating CD8+ cytotoxic Tcells in human cancers
Published in Cellular oncology (Dordrecht) (01-08-2021)“…Purpose Expansion of CD8 + cytotoxic Tlymphocytes is a prerequisite for anti-cancer immune activity and has gained interest in the era of immune checkpoint…”
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p63 expression in human tumors and normal tissues: a tissue microarray study on 10,200 tumors
Published in Biomarker research (25-01-2021)“…Tumor protein 63 (p63) is a transcription factor of the p53 gene family involved in differentiation of several tissues including squamous epithelium. p63…”
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E-Cadherin expression in human tumors: a tissue microarray study on 10,851 tumors
Published in Biomarker research (05-06-2021)“…Abstract Background The E-Cadherin gene ( CDH1, Cadherin 1 ), located at 16q22.1 encodes for a calcium-dependent membranous glycoprotein with an important role…”
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Prostein expression in human tumors: a tissue microarray study on 19,202 tumors from 152 different Tumor entities
Published in Diagnostic pathology (13-01-2024)“…Prostein (P501S), also termed solute carrier family 45 member 3 (SLC45A3) is an androgen regulated protein which is preferentially expressed in prostate…”
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15
Prevalence and Significance of AGR2 Expression in Human Cancer
Published in Cancer medicine (Malden, MA) (01-11-2024)“…ABSTRACT Backround Anterior gradient 2 (AGR2) is a resident endoplasmic reticulum (ER) protein with a vital role in embryonal development, mucus maturation,…”
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Elevated MUC5AC expression is associated with mismatch repair deficiency and proximal tumor location but not with cancer progression in colon cancer
Published in Medical molecular morphology (01-06-2021)“…Mucin 5AC (MUC5AC) is a secreted gel-forming mucin expressed by several epithelia. In the colon, MUC5AC is expressed in scattered normal epithelial cells but…”
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Pattern of placental alkaline phosphatase (PLAP) expression in human tumors: a tissue microarray study on 12,381 tumors
Published in The journal of pathology. Clinical research (01-11-2021)“…Placental alkaline phosphatase (PLAP) is commonly expressed at high levels in testicular germ cell tumors. PLAP immunohistochemistry (IHC) is thus often used…”
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Mammaglobin-A Expression Is Highly Specific for Tumors Derived from the Breast, the Female Genital Tract, and the Salivary Gland
Published in Diagnostics (Basel) (01-03-2023)“…Human mammaglobin-A (SCGB2A2) is a secretory protein with an unknown function that is used as a diagnostic marker for breast cancer. However, other tumors can…”
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Expression of Trefoil Factor 1 (TFF1) in Cancer: A Tissue Microarray Study Involving 18,878 Tumors
Published in Diagnostics (Basel) (28-09-2024)“…Trefoil factor 1 (TFF1) plays a role in the mucus barrier. To evaluate the prevalence of TFF1 expression in cancer, a tissue microarray containing 18,878…”
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Epithelial Cell Adhesion Molecule (EpCAM) Expression in Human Tumors: A Comparison with Pan-Cytokeratin and TROP2 in 14,832 Tumors
Published in Diagnostics (Basel) (01-05-2024)“…EpCAM is expressed in many epithelial tumors and is used for the distinction of malignant mesotheliomas from adenocarcinomas and as a surrogate pan-epithelial…”
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