Search Results - "Menyhárt, Ákos"

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    Spectral and Multifractal Signature of Cortical Spreading Depolarisation in Aged Rats by Makra, Péter, Menyhárt, Ákos, Bari, Ferenc, Farkas, Eszter

    Published in Frontiers in physiology (08-11-2018)
    “…Cortical spreading depolarisation (CSD) is a transient disruption of ion balance that propagates along the cortex. It has been identified as an important…”
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    Journal Article
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    Comparative analysis of spreading depolarizations in brain slices exposed to osmotic or metabolic stress by Frank, Rita, Bari, Ferenc, Menyhárt, Ákos, Farkas, Eszter

    Published in BMC neuroscience (03-05-2021)
    “…Recurrent spreading depolarizations (SDs) occur in stroke and traumatic brain injury and are considered as a hallmark of injury progression. The complexity of…”
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    Journal Article
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    Nimodipine exerts a protective effect against spreading depolarization and neuroinflammation by Frank, Rita, Pesti, István, Menyhárt, Ákos, Szarvas, Péter, Gulya, Károly, Bari, Ferenc, Farkas, Eszter

    Published in Physiology (Bethesda, Md.) (01-05-2023)
    “…Abstract only Hypothesis, objective: Voltage gated Ca2+ channels (VGCCs) are widely expressed in the central nervous system and implicated in neuronal injury…”
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    Journal Article
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    Collateral is brain: Low perfusion triggers spreading depolarization and futile reperfusion after acute ischemic stroke by Törteli, Anna, Tóth, Réka, Bari, Ferenc, Farkas, Eszter, Menyhárt, Ákos

    “…Futile reperfusion is a phenomenon of inadequate perfusion despite successful recanalization after acute ischemic stroke (AIS). It is associated with poor…”
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    Journal Article
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    Nimodipine accelerates the restoration of functional hyperemia during spreading oligemia by Menyhárt, Ákos, Bálint, Armand Rafael, Kozák, Péter, Bari, Ferenc, Farkas, Eszter

    Published in Journal of neurochemistry (01-05-2024)
    “…Spreading depolarization (SD) is assumed to be the pathophysiological correlate of migraine aura, leading to spreading depression of activity and a…”
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    Journal Article
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    Spreading depolarization causes reperfusion failure after cerebral ischemia by Törteli, Anna, Tóth, Réka, Berger, Sarah, Samardzic, Sarah, Bari, Ferenc, Menyhárt, Ákos, Farkas, Eszter

    “…Despite successful recanalization, reperfusion failure associated with poor neurological outcomes develops in half of treated stroke patients. We explore here…”
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    Journal Article
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    Nimodipine augments cerebrovascular reactivity in aging but runs the risk of local perfusion reduction in acute cerebral ischemia by Kecskés, Szilvia, Menyhárt, Ákos, Bari, Ferenc, Farkas, Eszter

    Published in Frontiers in aging neuroscience (27-04-2023)
    “…The efficacy of cerebrovascular reactivity (CVR) is taken as an indicator of cerebrovascular health. We found that CVR tested with the inhalation of 10 % CO…”
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    Journal Article
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    Tissue Acidosis Associated with Ischemic Stroke to Guide Neuroprotective Drug Delivery by M Tóth, Orsolya, Menyhárt, Ákos, Frank, Rita, Hantosi, Dóra, Farkas, Eszter, Bari, Ferenc

    Published in Biology (Basel, Switzerland) (11-12-2020)
    “…Ischemic stroke is a leading cause of death and disability worldwide. Yet, the effective therapy of focal cerebral ischemia has been an unresolved challenge…”
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    Journal Article
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    Astrocyte Ca 2+ Waves and Subsequent Non-Synchronized Ca 2+ Oscillations Coincide with Arteriole Diameter Changes in Response to Spreading Depolarization by Tóth, Réka, Farkas, Attila E, Krizbai, István A, Makra, Péter, Bari, Ferenc, Farkas, Eszter, Menyhárt, Ákos

    “…Spreading depolarization (SD) is a wave of mass depolarization that causes profound perfusion changes in acute cerebrovascular diseases. Although the astrocyte…”
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    Journal Article
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    The Impact of Aging on Spreading Depolarization in the Intact and Ischemic Rat Brain by Ákos, Menyhárt

    Published 01-01-2017
    “…Background: Aging emerges as a major independent risk factor for the incidence and prevalence of ischemic stroke and predicts poor patient outcomes 41, 42 . In…”
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    Dissertation
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    Nimodipine inhibits spreading depolarization, ischemic injury, and neuroinflammation in mouse live brain slice preparations by Frank, Rita, Szarvas, Péter Archibald, Pesti, István, Zsigmond, Anna, Berkecz, Róbert, Menyhárt, Ákos, Bari, Ferenc, Farkas, Eszter

    Published in European journal of pharmacology (15-08-2024)
    “…Nimodipine is used to prevent delayed ischemic deficit in patients with aneurysmal subarachnoid hemorrhage (aSAH). Spreading depolarization (SD) is recognized…”
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    Journal Article
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    Susceptibility of the cerebral cortex to spreading depolarization in neurological disease states: The impact of aging by Hertelendy, Péter, Varga, Dániel P., Menyhárt, Ákos, Bari, Ferenc, Farkas, Eszter

    Published in Neurochemistry international (01-07-2019)
    “…Secondary injury following acute brain insults significantly contributes to poorer neurological outcome. The spontaneous, recurrent occurrence of spreading…”
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    Journal Article
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    IGF‐1 deficiency impairs neurovascular coupling in mice: implications for cerebromicrovascular aging by Toth, Peter, Tarantini, Stefano, Ashpole, Nicole M., Tucsek, Zsuzsanna, Milne, Ginger L., Valcarcel‐Ares, Noa M., Menyhart, Akos, Farkas, Eszter, Sonntag, William E., Csiszar, Anna, Ungvari, Zoltan

    Published in Aging cell (01-12-2015)
    “…Summary Aging is associated with marked deficiency in circulating IGF‐1, which has been shown to contribute to age‐related cognitive decline. Impairment of…”
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    Journal Article
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    Large-conductance Ca2+-activated potassium channels are potently involved in the inverse neurovascular response to spreading depolarization by Menyhárt, Ákos, Farkas, Attila E., Varga, Dániel P., Frank, Rita, Tóth, Réka, Bálint, Armand R., Makra, Péter, Dreier, Jens P., Bari, Ferenc, Krizbai, István A., Farkas, Eszter

    Published in Neurobiology of disease (01-11-2018)
    “…Recurrent spreading depolarizations occur in the cerebral cortex from minutes up to weeks following acute brain injury. Clinical evidence suggests that the…”
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    Journal Article
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