Search Results - "Menta, Ramon"
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Comparative Analysis between the In Vivo Biodistribution and Therapeutic Efficacy of Adipose-Derived Mesenchymal Stromal Cells Administered Intraperitoneally in Experimental Colitis
Published in International journal of molecular sciences (23-06-2018)“…Mesenchymal stem cells (MSCs) have emerged as a promising treatment for inflammatory diseases. The immunomodulatory effect of MSCs takes place both by direct…”
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Intralymphatic Administration of Adipose Mesenchymal Stem Cells Reduces the Severity of Collagen-Induced Experimental Arthritis
Published in Frontiers in immunology (21-04-2017)“…Mesenchymal stem cells (MSCs) are multipotent stromal cells with immunomodulatory properties. They have emerged as a very promising treatment for autoimmunity…”
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Biodistribution and Efficacy of Human Adipose-Derived Mesenchymal Stem Cells Following Intranodal Administration in Experimental Colitis
Published in Frontiers in immunology (08-06-2017)“…Mesenchymal stem cells (MSCs) have a large potential in cell therapy for treatment of inflammatory and autoimmune diseases, thanks to their immunomodulatory…”
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Adipose‐derived mesenchymal stromal cells modulate experimental autoimmune arthritis by inducing an early regulatory innate cell signature
Published in Immunity, Inflammation and Disease (01-06-2016)“…Modulation of innate immune responses in rheumatoid arthritis and other immune‐mediated disorders is of critical importance in the clinic since a growing body…”
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Human adipose mesenchymal stem cells modulate myeloid cells toward an anti-inflammatory and reparative phenotype: role of IL-6 and PGE2
Published in Stem cell research & therapy (02-11-2020)“…Mesenchymal stem cells (MSCs) activate the endogenous immune regulatory system, inducing a therapeutic effect in recipients. MSCs have demonstrated the ability…”
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Dissecting Allo-Sensitization After Local Administration of Human Allogeneic Adipose Mesenchymal Stem Cells in Perianal Fistulas of Crohn's Disease Patients
Published in Frontiers in immunology (14-06-2019)“…Adipose mesenchymal stem cells (ASC) are considered minimally immunogenic. This is due to the low expression of human leukocyte antigens I (HLA-I), lack of…”
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Requirement of IFN-gamma-mediated indoleamine 2,3-dioxygenase expression in the modulation of lymphocyte proliferation by human adipose-derived stem cells
Published in Tissue engineering. Part A (01-10-2009)“…Human adipose-derived mesenchymal stem cells (hASCs) are mesenchymal stem cells (MSCs) with reduced immunogenicity and capability to modulate immune responses…”
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Toll-like receptor-mediated signaling in human adipose-derived stem cells: implications for immunogenicity and immunosuppressive potential
Published in Tissue engineering. Part A (01-07-2009)“…Human adipose-derived stem cells (hASCs) are mesenchymal stem cells with reduced immunogenicity and the capability to modulate immune responses. These…”
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Human adipose-derived stem cells impair natural killer cell function and exhibit low susceptibility to natural killer-mediated lysis
Published in Stem cells and development (20-05-2012)“…Human adipose-derived stem cells (hASCs) have been successfully used in treating numerous diseases. However, several aspects need to be considered,…”
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Human cardiac stem cells inhibit lymphocyte proliferation through paracrine mechanisms that correlate with indoleamine 2,3-dioxygenase induction and activity
Published in Stem cell research & therapy (25-10-2018)“…Transplantation of allogeneic human cardiac/stem progenitor cells (hCSCs) is currently being tested in several phase I/II clinical trials as a novel and…”
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Human Cardiac-Derived Stem/Progenitor Cells Fine-Tune Monocyte-Derived Descendants Activities toward Cardiac Repair
Published in Frontiers in immunology (26-10-2017)“…Cardiac repair following MI relies on a finely regulated immune response involving sequential recruitment of monocytes to the injured tissue. Monocyte-derived…”
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T Lymphocyte Prestimulation Impairs in a Time-Dependent Manner the Capacity of Adipose Mesenchymal Stem Cells to Inhibit Proliferation: Role of Interferon γ, Poly I:C, and Tryptophan Metabolism in Restoring Adipose Mesenchymal Stem Cell Inhibitory Effect
Published in Stem cells and development (15-09-2015)“…The immunomodulatory properties of mesenchymal stem/stromal cells (MSCs) make them an attractive therapeutic tool to treat chronic inflammatory diseases, such…”
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Tryptophan concentration is the main mediator of the capacity of adipose mesenchymal stromal cells to inhibit T-lymphocyte proliferation in vitro
Published in Cytotherapy (Oxford, England) (01-12-2014)“…Abstract Background aims Mesenchymal stromal cells (MSCs) have immunomodulatory properties that are mediated by cell-to-cell interactions and paracrine effects…”
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Endoscopic submucosal injection of adipose-derived mesenchymal stem cells ameliorates TNBS-induced colitis in rats and prevents stenosis
Published in Stem cell research & therapy (10-04-2018)“…Mesenchymal stem cells have potential applications in inflammatory bowel disease due to their immunomodulatory properties. Our aim was to evaluate the…”
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Human Adipose‐Derived Mesenchymal Stem Cells Modulate Experimental Autoimmune Arthritis by Modifying Early Adaptive T Cell Responses
Published in Stem cells (Dayton, Ohio) (01-12-2015)“…Mesenchymal stem cells (MSCs) are multipotent stromal cells with immunosuppressive properties. They have emerged as a very promising treatment for autoimmunity…”
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Human adipose tissue–derived mesenchymal stromal cells promote B-cell motility and chemoattraction
Published in Cytotherapy (Oxford, England) (01-12-2014)“…Abstract Background aims Mesenchymal stromal cells hold special interest for cell-based therapy because of their tissue-regenerative and immunosuppressive…”
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Adipose mesenchymal stromal cell function is not affected by methotrexate and azathioprine
Published in BioResearch open access (01-12-2013)“…Given their capacity to modulate the immune response, adipose mesenchymal stem or stromal cells (ASCs) have been used as therapeutic tools to treat chronic…”
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