Search Results - "Mensinga, Tjeert"
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Toll-like receptor 3 blockade in rhinovirus-induced experimental asthma exacerbations: A randomized controlled study
Published in Journal of allergy and clinical immunology (01-04-2018)“…Human rhinoviruses (HRVs) commonly precipitate asthma exacerbations. Toll-like receptor 3, an innate pattern recognition receptor, is triggered by HRV, driving…”
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2
Cannabinoid modulations of resting state EEG θ power and working memory are correlated in humans
Published in Journal of cognitive neuroscience (01-09-2010)“…Object representations in working memory depend on neural firing that is phase-locked to oscillations in the theta band (4-8 Hz). Cannabis intake disrupts…”
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3
Cognitive and psychomotor effects in males after smoking a combination of tobacco and cannabis containing up to 69 mg delta-9-tetrahydrocannabinol (THC)
Published in Psychopharmacologia (01-05-2009)“…Rationale Δ 9 -Tetrahydrocannabinol (THC) is the main active constituent of cannabis. In recent years, the average THC content of some cannabis cigarettes has…”
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4
Delta-9-tetrahydrocannabinol (THC) serum concentrations and pharmacological effects in males after smoking a combination of tobacco and cannabis containing up to 69 mg THC
Published in Psychopharmacologia (01-12-2008)“…Rationale Δ 9 -Tetrahydrocannabinol (THC) is the main active constituent of cannabis. In recent years, the average THC content of some cannabis cigarettes has…”
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5
Potato glycoalkaloids and adverse effects in humans: an ascending dose study
Published in Regulatory toxicology and pharmacology (01-02-2005)“…Glycoalkaloids in potatoes may induce gastro-intestinal and systemic effects, by cell membrane disruption and acetylcholinesterase inhibition, respectively…”
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6
Safety and immunogenicity of influenza whole inactivated virus vaccines: A phase I randomized clinical trial
Published in Human vaccines & immunotherapeutics (03-04-2015)“…BACKGROUND: Influenza vaccine production capacity is still insufficient to meet global demand in case of a pandemic. To expand worldwide influenza vaccine…”
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7
Health implications of exposure to Environmental nitrogenous compounds
Published in Toxicological reviews (2003)“…All living systems need nitrogen for the production of complex organic molecules, such as proteins, nucleic acids, vitamins, hormones and enzymes. Due to the…”
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8
Disposition of smoked cannabis with high Δ(9)-tetrahydrocannabinol content: a kinetic model
Published in Toxicology and applied pharmacology (01-08-2010)“…No model exists to describe the disposition and kinetics of inhaled cannabis containing a high THC dose. We aimed to develop a kinetic model providing…”
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THE PHARMACOKINETICS OF GLYCYRRHIZIC ACID EVALUATED BY PHYSIOLOGICALLY BASED PHARMACOKINETIC MODELING
Published in Drug metabolism reviews (01-01-2001)“…Glycyrrhizic acid is widely applied as a sweetener in food products and chewing tobacco. In addition, it is of clinical interest for possible treatment of…”
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10
Determinants of Maximally Attained Level of Pulmonary Function
Published in American journal of respiratory and critical care medicine (15-04-2004)“…This study investigated the determinants of sex-specific maximally attained levels of FEV(1), VC, and the ratio of FEV(1) to VC. Subjects were between the ages…”
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11
Disposition of smoked cannabis with high Δ9-tetrahydrocannabinol content: A kinetic model
Published in Toxicology and applied pharmacology (01-08-2010)“…No model exists to describe the disposition and kinetics of inhaled cannabis containing a high THC dose. We aimed to develop a kinetic model providing…”
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12
A Dose-Escalating Study With the Fetal Estrogen Estetrol in Healthy Men
Published in The journal of clinical endocrinology and metabolism (01-09-2018)“…Luteinizing hormone-releasing hormone (LHRH) agonists have replaced estrogens for endocrine treatment of advanced prostate cancer (PC) because of…”
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13
Effect of mavoglurant (AFQ056), a selective mGluR5 antagonist, on the pharmacokinetics of a combined oral contraceptive containing ethinyl estradiol and levonorgestrel in healthy women
Published in International journal of clinical pharmacology and therapeutics (01-07-2015)“…To compare the pharmacokinetics (PKs) of a combination oral contraceptive (OC) when given alone or concomitantly with the selective metabotropic glutamate…”
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14
Disposition of smoked cannabis with high 9-tetrahydrocannabinol content: A kinetic model
Published in Toxicology and applied pharmacology (01-08-2010)“…No model exists to describe the disposition and kinetics of inhaled cannabis containing a high THC dose. We aimed to develop a kinetic model providing…”
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15
The relationship of eosinophilia and positive skin test reactivity to respiratory symptom prevalence in a community-based population study
Published in Journal of allergy and clinical immunology (01-07-1990)“…We studied the relationship of the prevalence of a variety of respiratory symptoms to positive skin test reactivity (skin test index greater than or equal to…”
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16
Cognitive and psychomotor effects in males after smoking a combination of tobacco and cannabis containing up to 69mg delta-9-tetrahydrocannabinol (THC)
Published in Psychopharmacology (01-05-2009)“…Rationale: Delta 9-Tetrahydrocannabinol (THC) is the main active constituent of cannabis. In recent years, the average THC content of some cannabis cigarettes…”
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Journal Article -
17
Disposition of smoked cannabis with high {Delta}{sup 9}-tetrahydrocannabinol content: A kinetic model
Published in Toxicology and applied pharmacology (01-08-2010)“…Introduction: No model exists to describe the disposition and kinetics of inhaled cannabis containing a high THC dose. We aimed to develop a kinetic model…”
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18
A human physiologically-based model for glycyrrhzic acid, a compound subject to presystemic metabolism and enterohepatic cycling
Published in Pharmaceutical research (01-12-2000)“…To analyze the role of the kinetics of glycyrrhizic acid (GD) in its toxicity. A physiologically-based pharmacokinetic (PBPK) model that has been developed for…”
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A Population Physiologically Based Pharmacokinetic/Pharmacodynamic Model for the Inhibition of 11-β-Hydroxysteroid Dehydrogenase Activity by Glycyrrhetic Acid
Published in Toxicology and applied pharmacology (01-01-2001)“…Glycyrrhizic acid is widely applied as a sweetener in food products and chewing tobacco. Habitual consumption of this compound may lead to hypertension and…”
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20
IPV-Vero Vaccine Induces a Strong Booster Reaction and is Well Tolerated in Adults
Published in Scandinavian journal of infectious diseases (1998)“…A phase 1-2 trial was conducted in 48 adults to study safety and immunogenicity of an inactivated poliovirus vaccine produced using Vero cells (IPV-Vero)…”
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