Search Results - "Mensà, Emanuela"

Small extracellular vesicles deliver miR-21 and miR-217 as pro-senescence effectors to endothelial cells by Mensà, Emanuela, Guescini, Michele, Giuliani, Angelica, Bacalini, Maria Giulia, Ramini, Deborah, Corleone, Giacomo, Ferracin, Manuela, Fulgenzi, Gianluca, Graciotti, Laura, Prattichizzo, Francesco, Sorci, Leonardo, Battistelli, Michela, Monsurrò, Vladia, Bonfigli, Anna Rita, Cardelli, Maurizio, Recchioni, Rina, Marcheselli, Fiorella, Latini, Silvia, Maggio, Serena, Fanelli, Mirco, Amatori, Stefano, Storci, Gianluca, Ceriello, Antonio, Stocchi, Vilberto, De Luca, Maria, Magnani, Luca, Rippo, Maria Rita, Procopio, Antonio Domenico, Sala, Claudia, Budimir, Iva, Bassi, Cristian, Negrini, Massimo, Garagnani, Paolo, Franceschi, Claudio, Sabbatinelli, Jacopo, Bonafè, Massimiliano, Olivieri, Fabiola

“…The role of epigenetics in endothelial cell senescence is a cutting-edge topic in ageing research. However, little is known of the relative contribution to…”
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The telomere world and aging: Analytical challenges and future perspectives by Mensà, Emanuela, Latini, Silvia, Ramini, Deborah, Storci, Gianluca, Bonafè, Massimiliano, Olivieri, Fabiola

“…Telomeres, the terminal nucleoprotein structures of eukaryotic chromosomes, play pleiotropic functions in cellular and organismal aging. Telomere length (TL)…”
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Bone marrow adipocytes support hematopoietic stem cell survival by Mattiucci, Domenico, Maurizi, Giulia, Izzi, Valerio, Cenci, Lorenzo, Ciarlantini, Marco, Mancini, Stefania, Mensà, Emanuela, Pascarella, Raffaele, Vivarelli, Marco, Olivieri, Attilio, Leoni, Pietro, Poloni, Antonella

“…In bone marrow (BM), hematopoietic elements are mingled with adipocytes (BM‐A), which are the most abundant stromal component in the niche. BM‐A progressively…”
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Pleiotropic effects of metformin: Shaping the microbiome to manage type 2 diabetes and postpone ageing by Prattichizzo, Francesco, Giuliani, Angelica, Mensà, Emanuela, Sabbatinelli, Jacopo, De Nigris, Valeria, Rippo, Maria Rita, La Sala, Lucia, Procopio, Antonio Domenico, Olivieri, Fabiola, Ceriello, Antonio

“…Metformin is the first-choice therapy to lower glycaemia and manage type 2 diabetes. Continuously emerging epidemiological data and experimental models are…”
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Circulating miR-146a in healthy aging and type 2 diabetes: Age- and gender-specific trajectories by Mensà, Emanuela, Giuliani, Angelica, Matacchione, Giulia, Gurău, Felicia, Bonfigli, Anna Rita, Romagnoli, Fabio, De Luca, Maria, Sabbatinelli, Jacopo, Olivieri, Fabiola

“…•Circulating microRNA-146a levels show a significant age-related decline.•MiR-146a shows gender-related correlations with specific biochemical…”
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Genomic stability, anti-inflammatory phenotype, and up-regulation of the RNAseH2 in cells from centenarians by Storci, Gianluca, De Carolis, Sabrina, Papi, Alessio, Bacalini, Maria Giulia, Gensous, Noémie, Marasco, Elena, Tesei, Anna, Fabbri, Francesco, Arienti, Chiara, Zanoni, Michele, Sarnelli, Anna, Santi, Spartaco, Olivieri, Fabiola, Mensà, Emanuela, Latini, Silvia, Ferracin, Manuela, Salvioli, Stefano, Garagnani, Paolo, Franceschi, Claudio, Bonafè, Massimiliano

“…Current literature agrees on the notion that efficient DNA repair favors longevity across evolution. The DNA damage response machinery activates inflammation…”
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Long-term exposure of human endothelial cells to metformin modulates miRNAs and isomiRs by Giuliani, Angelica, Londin, Eric, Ferracin, Manuela, Mensà, Emanuela, Prattichizzo, Francesco, Ramini, Deborah, Marcheselli, Fiorella, Recchioni, Rina, Rippo, Maria Rita, Bonafè, Massimiliano, Rigoutsos, Isidore, Olivieri, Fabiola, Sabbatinelli, Jacopo

“…Increasing evidence suggest that the glucose-lowering drug metformin exerts a valuable anti-senescence role. The ability of metformin to affect the biogenesis…”
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Exosome-based immunomodulation during aging: A nano-perspective on inflamm-aging by Prattichizzo, Francesco, Micolucci, Luigina, Cricca, Monica, De Carolis, Sabrina, Mensà, Emanuela, Ceriello, Antonio, Procopio, Antonio Domenico, Bonafè, Massimiliano, Olivieri, Fabiola

“…•Exosomes are involved in immune system recognition.•Exosomal alteration was observed during aging and age-related diseases.•Exosomes can play opposing roles…”
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Pre-eclampsia predictive ability of maternal miR-125b: a clinical and experimental study by Licini, Caterina, Avellini, Chiara, Picchiassi, Elena, Mensà, Emanuela, Fantone, Sonia, Ramini, Deborah, Tersigni, Chiara, Tossetta, Giovanni, Castellucci, Clara, Tarquini, Federica, Coata, Giuliana, Giardina, Irene, Ciavattini, Andrea, Scambia, Giovanni, Di Renzo, Gian Carlo, Di Simone, Nicoletta, Gesuita, Rosaria, Giannubilo, Stefano R., Olivieri, Fabiola, Marzioni, Daniela

“…Pre-eclampsia (PE) is a systemic maternal syndrome affecting 2-8% of pregnancies worldwide and involving poor placental perfusion and impaired blood supply to…”
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Connections from the rat dorsal column nuclei (DCN) to the periaqueductal gray matter (PAG) by Barbaresi, Paolo, Mensà, Emanuela

“…•This study describes the anatomical connection between the DCN and the PAG.•The projection is somatotopically organized.•This projection could be part of the…”
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Microstructured soft devices for the growth and analysis of populations of homogenous multicellular tumor spheroids by Tartagni, Ottavia, Borók, Alexandra, Mensà, Emanuela, Bonyár, Attila, Monti, Barbara, Hofkens, Johan, Porcelli, Anna Maria, Zuccheri, Giampaolo

“…Multicellular tumor spheroids are rapidly emerging as an improved in vitro model with respect to more traditional 2D culturing. Microwell culturing is a simple…”
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A Functional Survey of the Regulatory Landscape of Estrogen Receptor-Positive Breast Cancer Evolution by Barozzi, Iros, Slaven, Neil, Canale, Eleonora, Lopes, Rui, Amorim Monteiro Barbosa, Inês, Bleu, Melusine, Ivanoiu, Diana, Pacini, Claudia, Mensa', Emanuela, Chambers, Alfie, Bravaccini, Sara, Ravaioli, Sara, Győrffy, Balázs, Dieci, Maria Vittoria, Pruneri, Giancarlo, Galli, Giorgio Giacomo, Magnani, Luca

“…Only a handful of somatic alterations have been linked to endocrine therapy resistance in hormone-dependent breast cancer, potentially explaining ∼40% of…”
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Postnatal development of the distribution of nitric oxide-producing neurons in the rat corpus callosum by Barbaresi, Paolo, Mensà, Emanuela, Sagrati, Andrea, Graciotti, Laura

“…•NADPH-d-Hi was used to study the postnatal development of NO-producing neurons in the rat cc.•Intracallosal NADPH-d+Ns were detected at P0, their number…”
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MiR-21-5p and miR-126a-3p levels in plasma and circulating angiogenic cells: relationship with type 2 diabetes complications by Olivieri, Fabiola, Spazzafumo, Liana, Bonafè, Massimiliano, Recchioni, Rina, Prattichizzo, Francesco, Marcheselli, Fiorella, Micolucci, Luigina, Mensà, Emanuela, Giuliani, Angelica, Santini, Gabriele, Gobbi, Mirko, Lazzarini, Raffaella, Boemi, Massimo, Testa, Roberto, Antonicelli, Roberto, Procopio, Antonio Domenico, Bonfigli, Anna Rita

“…Innovative biomarkers are required to manage type 2 diabetic patients (T2DM). We focused our study on miR-126-3p and miR-21-5p levels, as biomarkers of…”
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The mitomiR/Bcl-2 axis affects mitochondrial function and autophagic vacuole formation in senescent endothelial cells by Giuliani, Angelica, Cirilli, Ilenia, Prattichizzo, Francesco, Mensà, Emanuela, Fulgenzi, Gianluca, Sabbatinelli, Jacopo, Graciotti, Laura, Olivieri, Fabiola, Procopio, Antonio Domenico, Tiano, Luca, Rippo, Maria Rita

“…During senescence, cells undergo distinctive biochemical and morphological changes and become dysfunctional. MiRNAs are involved in the senescence process and…”
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Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging by Scavello, Francesco, Zeni, Filippo, Tedesco, Calogero C, Mensà, Emanuela, Veglia, Fabrizio, Procopio, Antonio Domenico, Bonfigli, Anna Rita, Olivieri, Fabiola, Raucci, Angela

“…The receptor for advanced glycation end-products (RAGE) recognizes several ligands involved in inflammatory diseases. Two circulating soluble isoforms exist:…”
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Epigenetic effects of physical activity in elderly patients with cardiovascular disease by Recchioni, Rina, Marcheselli, Fiorella, Antonicelli, Roberto, Mensà, Emanuela, Lazzarini, Raffaella, Procopio, Antonio Domenico, Olivieri, Fabiola

“…Cardiovascular disease (CVD) is an important public health problem affecting especially the elderly. Over the past 20years, an increasing number of studies…”
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MiR-422a promotes adipogenesis via MeCP2 downregulation in human bone marrow mesenchymal stem cells by Giuliani, Angelica, Sabbatinelli, Jacopo, Amatori, Stefano, Graciotti, Laura, Silvestrini, Andrea, Matacchione, Giulia, Ramini, Deborah, Mensà, Emanuela, Prattichizzo, Francesco, Babini, Lucia, Mattiucci, Domenico, Busilacchi, Elena Marinelli, Bacalini, Maria Giulia, Espinosa, Emma, Lattanzio, Fabrizia, Procopio, Antonio Domenico, Olivieri, Fabiola, Poloni, Antonella, Fanelli, Mirco, Rippo, Maria Rita

“…Methyl-CpG binding protein 2 (MeCP2) is a ubiquitous transcriptional regulator. The study of this protein has been mainly focused on the central nervous system…”
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Physical activity and progenitor cell-mediated endothelial repair in chronic heart failure: Is there a role for epigenetics? by Recchioni, Rina, Marcheselli, Fiorella, Antonicelli, Roberto, Lazzarini, Raffaella, Mensà, Emanuela, Testa, Roberto, Procopio, Antonio Domenico, Olivieri, Fabiola

“…•Regular physical activity has been accepted as a highly effective and safe treatment for chronic heart failure (CHF).•Exercise training (ET) promotes…”
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Physical Activity Modulates the Overexpression of the Inflammatory miR‐146a‐5p in Obese Patients by Russo, Angelo, Bartolini, Desireé, Mensà, Emanuela, Torquato, Pierangelo, Albertini, Maria Cristina, Olivieri, Fabiola, Testa, Roberto, Rossi, Sara, Piroddi, Marta, Cruciani, Gabriele, De Feo, Pierpaolo, Galli, Francesco

“…s Specific microRNAs (miRs), including the “angio‐miR‐126” and the “inflamma‐miR‐146a‐5p,” have been proposed as biomarkers and even therapeutic targets of…”
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