Search Results - "Menon, Renuka T."

Long-term pulmonary and cardiovascular morbidities of neonatal hyperoxia exposure in mice by Menon, Renuka T., Shrestha, Amrit Kumar, Reynolds, Corey L., Barrios, Roberto, Shivanna, Binoy

“…•Magnetic resonance imaging can reliably phenotype murine right ventricular function.•Neonatal hyperoxia exposure leads to persistent pulmonary hypertension in…”
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Tie-2 Cre-Mediated Deficiency of Extracellular Signal-Regulated Kinase 2 Potentiates Experimental Bronchopulmonary Dysplasia-Associated Pulmonary Hypertension in Neonatal Mice by Menon, Renuka T, Shrestha, Amrit Kumar, Barrios, Roberto, Reynolds, Corey, Shivanna, Binoy

“…Bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension (PH) is a significant lung morbidity of infants, and disrupted lung angiogenesis is a…”
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Extracellular Signal-Regulated Kinase 1 Alone Is Dispensable for Hyperoxia-Mediated Alveolar and Pulmonary Vascular Simplification in Neonatal Mice by Menon, Renuka T., Thapa, Shyam, Shrestha, Amrit Kumar, Barrios, Roberto, Shivanna, Binoy

“…Bronchopulmonary dysplasia (BPD) is a morbid lung disease distinguished by lung alveolar and vascular simplification. Hyperoxia, an important BPD causative…”
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Endothelial Adenosine Monophosphate-Activated Protein Kinase-Alpha1 Deficiency Potentiates Hyperoxia-Induced Experimental Bronchopulmonary Dysplasia and Pulmonary Hypertension by Elsaie, Ahmed, Menon, Renuka T, Shrestha, Amrit K, Gowda, Sharada H, Varghese, Nidhy P, Barrios, Roberto J, Blanco, Cynthia L, Konduri, Girija G, Shivanna, Binoy

“…Bronchopulmonary dysplasia and pulmonary hypertension, or BPD-PH, are serious chronic lung disorders of prematurity, without curative therapies. Hyperoxia, a…”
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Interactive and independent effects of early lipopolysaccharide and hyperoxia exposure on developing murine lungs by Shrestha, Amrit Kumar, Menon, Renuka T, El-Saie, Ahmed, Barrios, Roberto, Reynolds, Corey, Shivanna, Binoy

“…Bronchopulmonary dysplasia (BPD)-associated pulmonary hypertension (PH) is a chronic infantile lung disease that lacks curative therapies. Infants with…”
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Adrenomedullin Deficiency Potentiates Lipopolysaccharide-Induced Experimental Bronchopulmonary Dysplasia in Neonatal Mice by Shrestha, Amrit K., Menon, Renuka T., Yallampalli, Chandrasekhar, Barrios, Roberto, Shivanna, Binoy

“…Lung inflammation interrupts alveolarization and causes bronchopulmonary dysplasia (BPD). Besides mechanical ventilation and hyperoxia, sepsis contributes to…”
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Hyperoxia exposure disrupts adrenomedullin signaling in newborn mice: Implications for lung development in premature infants by Menon, Renuka T., Shrestha, Amrit Kumar, Shivanna, Binoy

“…Hyperoxia contributes to the development of bronchopulmonary dysplasia (BPD), a chronic lung disease of human infants that is characterized by disrupted lung…”
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Adrenomedullin Is Necessary to Resolve Hyperoxia-Induced Experimental Bronchopulmonary Dysplasia and Pulmonary Hypertension in Mice by Menon, Renuka T., Shrestha, Amrit Kumar, Reynolds, Corey L., Barrios, Roberto, Caron, Kathleen M., Shivanna, Binoy

“…Bronchopulmonary dysplasia (BPD)–associated pulmonary hypertension (PH) is an infantile lung disease characterized by aberrant angiogenesis and impaired…”
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Leflunomide attenuates oxidative stress in fetal human lung endothelial cells via superoxide dismutase 2 and catalase by Shrestha, Amrit Kumar, Menon, Renuka T., Shivanna, Binoy

“…Hyperoxia-induced oxidative stress contributes to the pathogenesis of bronchopulmonary dysplasia (BPD), the most common respiratory morbidity of preterm…”
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Consequences of early postnatal lipopolysaccharide exposure on developing lungs in mice by Shrestha, Amrit Kumar, Bettini, Matthew L, Menon, Renuka T, Gopal, Vashisht Y N, Huang, Shixia, Edwards, Dean P, Pammi, Mohan, Barrios, Roberto, Shivanna, Binoy

“…Bronchopulmonary dysplasia (BPD) is a chronic lung disease of infants that is characterized by interrupted lung development. Postnatal sepsis causes BPD, yet…”
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Lung omics signatures in a bronchopulmonary dysplasia and pulmonary hypertension-like murine model by Shrestha, Amrit Kumar, Gopal, Vashisht Y N, Menon, Renuka T, Hagan, Joseph L, Huang, Shixia, Shivanna, Binoy

“…Bronchopulmonary dysplasia (BPD), the most common chronic lung disease in infants, is associated with long-term morbidities, including pulmonary hypertension…”
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Hyperoxia Disrupts Extracellular Signal-Regulated Kinases 1/2-Induced Angiogenesis in the Developing Lungs by Menon, Renuka T, Shrestha, Amrit Kumar, Barrios, Roberto, Shivanna, Binoy

“…Hyperoxia contributes to the pathogenesis of bronchopulmonary dysplasia (BPD), a chronic lung disease of infants that is characterized by interrupted…”
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Leflunomide induces NAD(P)H quinone dehydrogenase 1 enzyme via the aryl hydrocarbon receptor in neonatal mice by Shrestha, Amrit Kumar, Patel, Ananddeep, Menon, Renuka T., Jiang, Weiwu, Wang, Lihua, Moorthy, Bhagavatula, Shivanna, Binoy

“…Aryl hydrocarbon receptor (AhR) has been increasingly recognized to play a crucial role in normal physiological homeostasis. Additionally, disrupted AhR…”
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Suppression of experimental autoimmune myasthenia gravis by combination therapy: Pentoxifylline as a steroid-sparing agent by Menon, Renuka T.R, Feferman, Tali, Aricha, Revital, Souroujon, Miriam C, Fuchs, Sara

“…Abstract Myasthenia gravis (MG) is frequently treated by corticosteroids such as methylprednisolone. However, continuous treatment with steroids often results…”
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859 Regression of an immunologically ‘cold’ oral cancer model induced by modulation of the tumor microenvironment with DOXIL, anti-CTLA-4, and radiation by Brasil Da Costa, Fabio Henrique, Bhavane, Rohan, Veeramachaneni, Ratna, Cortes, Sofia, Latka, Sarah L, Badachhape, Andrew, Menon, Renuka TR, Bhandari, Prajwal, Ghaghada, Ketankumar B, Young, Simon, Annapragada, Ananth V, Sikora, Andrew

“…BackgroundThe immune-suppressive tumor microenvironment (TME) of oral cancer often hinders the effectiveness of standard treatments, including surgery,…”
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