Search Results - "Menon, M K"

Efficient Ultra Wideband Radar Based Non Invasive Early Breast Cancer Detection by Devika Menon, M K, Rodrigue, Joseph

“…Ultra Wideband radar systems have emerged as a good alternative for non-invasive and harmless breast cancer detection. In this paper, bistatic and monostatic…”
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Regulation of LH Receptor mRNA Binding Protein by miR-122 in Rat Ovaries by Menon, Bindu, Sinden, Jennifer, Franzo-Romain, Meghan, Botta, Raman Bhadradri, Menon, K. M. J

“…LH receptor (LHR) expression in the ovary is regulated by the RNA binding protein, (LHR mRNA binding protein [LRBP]), which has been identified as being…”
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Follicle-Stimulating Hormone Inhibits Adenosine 5′-Monophosphate-Activated Protein Kinase Activation and Promotes Cell Proliferation of Primary Granulosa Cells in Culture through an Akt-Dependent Pathway by Kayampilly, Pradeep P, Menon, K. M. J

“…FSH, acting through multiple signaling pathways, regulates the proliferation and growth of granulosa cells, which are critical for ovulation. The present study…”
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SREBP Plays a Regulatory Role in LH/hCG Receptor mRNA Expression in Human Granulosa-Lutein Cells by Li, Yin-Xia, Guo, Xingzi, Gulappa, Thippeswamy, Menon, Bindu, Menon, K M J

“…Abstract Context LH receptor (LHR) expression has been shown to be regulated posttranscriptionally by LHR mRNA binding protein (LRBP) in rodent and human…”
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miR-122 Regulates LH Receptor Expression by Activating Sterol Response Element Binding Protein in Rat Ovaries by Menon, Bindu, Gulappa, Thippeswamy, Menon, K. M. J

“…LH/human chorionic gonadotropin receptor (LHR) undergoes down-regulation during preovulatory LH surge or in response to exposure to a supraphysiological…”
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Luteinizing Hormone/Human Chorionic Gonadotropin-Mediated Activation of mTORC1 Signaling Is Required for Androgen Synthesis by Theca-Interstitial Cells by Palaniappan, Murugesan, Menon, K. M. J

“…LH triggers the biosynthesis of androgens in the theca-interstitial (T-I) cells of ovary through the activation of a cAMP-dependent pathway. We have previously…”
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AMPK Activation by Dihydrotestosterone Reduces FSH-Stimulated Cell Proliferation in Rat Granulosa Cells by Inhibiting ERK Signaling Pathway by Kayampilly, Pradeep P, Menon, K. M. J

“…We have previously reported that 5α-dihydrotestosterone (DHT) inhibits FSH-mediated granulosa cell proliferation by reducing cyclin D2 mRNA expression and…”
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Eukaryotic Initiation Factor 5A Plays an Essential Role in Luteinizing Hormone Receptor Regulation by Menon, Bindu, Gulappa, Thippeswamy, Menon, K. M. J

“…Down-regulation of LH receptor (LHR) in the ovary by its ligand is mediated by a specific RNA-binding protein, designated LH receptor mRNA–binding protein…”
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Luteinizing Hormone Receptor mRNA Down-Regulation Is Mediated through ERK-Dependent Induction of RNA Binding Protein by Menon, Bindu, Franzo-Romain, Megan, Damanpour, Shadi, Menon, K. M. J

“…Luteinzing Hormone (LH)-regulated ERK1/2 signaling is required for the LHR mRNA binding protein-mediated downregulation of LH Receptor mRNA. The ligand-induced…”
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Follicle-Stimulating Hormone Increases Tuberin Phosphorylation and Mammalian Target of Rapamycin Signaling through an Extracellular Signal-Regulated Kinase-Dependent Pathway in Rat Granulosa Cells by Kayampilly, Pradeep P, Menon, K. M. J

“…FSH-mediated regulation of mammalian target of rapamycin (mTOR) signaling in proliferating granulosa cells and the effect of dihydrotestosterone (DHT) on this…”
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Metformin: direct inhibition of rat ovarian theca-interstitial cell proliferation by Will, Matthew A., M.D, Palaniappan, Murugesan, Ph.D, Peegel, Helle, M.S, Kayampilly, Pradeep, Ph.D, Menon, K.M.J., Ph.D

“…Objective To determine whether metformin has direct effects on ovarian theca-interstitial (T-I) cell proliferation through activation of adenosine…”
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The role of Rab5a GTPase in endocytosis and post-endocytic trafficking of the hCG-human luteinizing hormone receptor complex by Gulappa, Thippeswamy, Clouser, Christine L., Menon, K. M. J.

“…This study examined the role of Rab5a GTPase in regulating hCG-induced internalization and trafficking of the hCG-LH receptor complex in transfected 293T…”
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Stimulatory Effect of Insulin on 5α-Reductase Type 1 (SRD5A1) Expression through an Akt-Dependent Pathway in Ovarian Granulosa Cells by Kayampilly, Pradeep P, Wanamaker, Brett L, Stewart, James A, Wagner, Carrie L, Menon, K. M. J

“…Elevated levels of 5α-reduced androgens have been shown to be associated with hyperandrogenism and hyperinsulinemia, the leading causes of ovulatory…”
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Dihydrotestosterone Inhibits Granulosa Cell Proliferation by Decreasing the Cyclin D2 mRNA Expression and Cell Cycle Arrest at G1 Phase by Pradeep, P. K, Li, Xiaoling, Peegel, Helle, Menon, K. M. J

“…Hyperandrogenism is known to perturb ovarian physiology resulting in anovulatory conditions. In the ovary, androgens produced by theca-interstitial cells are…”
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Regulation of Sterol Regulatory Element-Binding Transcription Factor 1a by Human Chorionic Gonadotropin and Insulin in Cultured Rat Theca-Interstitial Cells by Palaniappan, Murugesan, Menon, K.M.J

“…Theca-interstitial (T-I) cells of the ovary synthesize androgens in response to luteinizing hormone (LH). In pathological conditions such as polycystic ovarian…”
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Ribonucleic Acid Binding Protein-Mediated Regulation of Luteinizing Hormone Receptor Expression in Granulosa Cells: Relationship to Sterol Metabolism by Wang, Lei, Nair, Anil K, Menon, K. M. J

“…Posttranscriptional mechanism plays a crucial role in regulating LH receptor (LHR) expression in the ovary. We have identified a novel trans-factor, LHR mRNA…”
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Regulation of Luteinizing Hormone/Chorionic Gonadotropin Receptor Messenger Ribonucleic Acid Expression in the Rat Ovary: Relationship to Cholesterol Metabolism by Wang, Lei, Menon, K. M. J

“…Down-regulation of LH/human chorionic gonadotropin (hCG) receptor (LHR) mRNA in the ovary after the preovulatory LH surge or the administration of a…”
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Structure, function and regulation of gonadotropin receptors – A perspective by Menon, K.M.J., Menon, Bindu

“…► We provide current understanding of structure/function of gonadotropin receptors. ► We summarize post-transcriptional regulation of LH receptor expression. ►…”
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The Role of Luteinizing Hormone/Human Chorionic Gonadotropin Receptor-Specific mRNA Binding Protein in Regulating Receptor Expression in Human Ovarian Granulosa Cells by Nair, Anil K., Peegel, Helle, Menon, K. M. J.

“…Context: In normally cycling women, LH receptor mRNA expression undergoes transient down-regulation after the LH surge. The same phenomenon is also seen during…”
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Evidence that Palmitoylation of Carboxyl Terminus Cysteine Residues of the Human Luteinizing Hormone Receptor Regulates Postendocytic Processing by Munshi, Utpal M, Clouser, Christine L, Peegel, Helle, Menon, K. M. J

“…Palmitoylation is a well-conserved posttranslational modification among members of the G protein-coupled receptor superfamily. The present study examined the…”
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