Search Results - "Menon, Debashish"

Mammalian SWI/SNF collaborates with a polycomb-associated protein to regulate male germline transcription in the mouse by Menon, Debashish U, Shibata, Yoichiro, Mu, Weipeng, Magnuson, Terry

“…A deficiency in BRG1, the catalytic subunit of the SWI/SNF chromatin remodeling complex, results in a meiotic arrest during spermatogenesis. Here, we explore…”
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Mammalian SWI/SNF chromatin remodeler is essential for reductional meiosis in males by Menon, Debashish U., Kirsanov, Oleksandr, Geyer, Christopher B., Magnuson, Terry

“…The mammalian SWI/SNF nucleosome remodeler is essential for spermatogenesis. Here, we identify a role for ARID2, a PBAF (Polybromo - Brg1 Associated…”
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siRNAs from an X-linked satellite repeat promote X-chromosome recognition in Drosophila melanogaster by Menon, Debashish U., Coarfa, Cristian, Xiao, Weimin, Gunaratne, Preethi H., Meller, Victoria H.

“…Significance Modulation of X-linked gene expression is essential in organisms with XX females and XY males. Various strategies for global regulation of X…”
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The Mouse INO80 Chromatin-Remodeling Complex Is an Essential Meiotic Factor for Spermatogenesis by Serber, Daniel W, Runge, John S, Menon, Debashish U, Magnuson, Terry

“…The ability to faithfully transmit genetic information across generations via the germ cells is a critical aspect of mammalian reproduction. The process of…”
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RBBP4 dysfunction reshapes the genomic landscape of H3K27 methylation and acetylation and disrupts gene expression by Mu, Weipeng, Murcia, Noel S, Smith, Keriayn N, Menon, Debashish U, Yee, Della, Magnuson, Terry

“…RBBP4 is a subunit of the chromatin remodeling complexes known as Polycomb repressive complex 2 and histone deacetylase 1/2-containing complexes. These…”
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A role for siRNA in X-chromosome dosage compensation in Drosophila melanogaster by Menon, Debashish U, Meller, Victoria H

“…Sex-chromosome dosage compensation requires selective identification of X chromatin. How this occurs is not fully understood. We show that small interfering…”
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Key mediators of somatic ATR signaling localize to unpaired chromosomes in spermatocytes by Fedoriw, Andrew M, Menon, Debashish, Kim, Yuna, Mu, Weipeng, Magnuson, Terry

“…Meiotic silencing of unpaired chromatin (MSUC) occurs during the first meiotic prophase, as chromosomes that fail to pair are sequestered into a…”
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Rett Syndrome: Crossing the Threshold to Clinical Translation by Katz, David M, Bird, Adrian, Coenraads, Monica, Gray, Steven J, Menon, Debashish U, Philpot, Benjamin D, Tarquinio, Daniel C

“…Lying at the intersection between neurobiology and epigenetics, Rett syndrome (RTT) has garnered intense interest in recent years, not only from a broad range…”
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Identification of the Drosophila X chromosome: The long and short of it by Menon, Debashish U, Meller, Victoria H

“…The different dose of X chromosomes in males and females produces a potentially fatal imbalance in X-linked gene products. This imbalance is addressed by…”
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The Mouse INO80 Chromatin-Remodeling Complex Is an Essential Meiotic Factor for Spermatogenesis1 by Serber, Daniel W, Runge, John S, Menon, Debashish U, Magnuson, Terry

“…The ability to faithfully transmit genetic information across generations via the germ cells is a critical aspect of mammalian reproduction. The process of…”
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Imprinting of the Y Chromosome Influences Dosage Compensation in roX1 roX2 Drosophila melanogaster by Menon, Debashish U, Meller, Victoria H

“…Drosophila melanogaster males have a well-characterized regulatory system that increases X-linked gene expression. This essential process restores the balance…”
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Germ line imprinting in Drosophila: Epigenetics in search of function by Menon, Debashish U., Meller, Victoria

“…Germ line imprinting produces parent-specific differences in the behavior of chromosomes or expression of genes. Epigenetic marks, placed on chromosomes in the…”
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Generation of a useful roX1 allele by targeted gene conversion by Apte, Manasi S, Moran, Victoria A, Menon, Debashish U, Rattner, Barbara P, Barry, Kathryn Hughes, Zunder, Rachel M, Kelley, Richard, Meller, Victoria H

“…Methods for altering the sequence of endogenous Drosophila melanogaster genes remain labor-intensive. We have tested a relatively simple strategy that enables…”
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The Drosophila homolog of the mammalian imprint regulator, CTCF, maintains the maternal genomic imprint in Drosophila melanogaster by MacDonald, William A, Menon, Debashish, Bartlett, Nicholas J, Sperry, G Elizabeth, Rasheva, Vanya, Meller, Victoria, Lloyd, Vett K

“…CTCF is a versatile zinc finger DNA-binding protein that functions as a highly conserved epigenetic transcriptional regulator. CTCF is known to act as a…”
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Investigation of X chromosome recognition: The role of small RNA in Drosophila dosage compensation by Menon, Debashish U

“…In humans and flies, females have two X chromosomes but males have one X chromosome and one Y chromosome. This leads to a fatal imbalance in X-linked gene…”
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