Search Results - "Menko, FH"

Hereditary leiomyomatosis and renal cell cancer in families referred for fumarate hydratase germline mutation analysis by Smit, DL, Mensenkamp, AR, Badeloe, S, Breuning, MH, Simon, MEH, Van Spaendonck, KY, Aalfs, CM, Post, JG, Shanley, S, Krapels, IPC, Hoefsloot, LH, Van Moorselaar, RJA, Starink, TM, Bayley, J-P, Frank, J, Van Steensel, MAM, Menko, FH

“…Smit DL, Mensenkamp AR, Badeloe S, Breuning MH, Simon MEH, van Spaendonck KY, Aalfs CM, Post JG, Shanley S, Krapels IPC, Hoefsloot LH, van Moorselaar RJA,…”
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Cancer risks in BRCA2 families: estimates for sites other than breast and ovary by van Asperen, C J, Brohet, R M, Meijers-Heijboer, E J, Hoogerbrugge, N, Verhoef, S, Vasen, H F A, Ausems, M G E M, Menko, F H, Gomez Garcia, E B, Klijn, J G M, Hogervorst, F B L, van Houwelingen, J C, van’t Veer, L J, Rookus, M A, van Leeuwen, F E

“…Background: In BRCA2 mutation carriers, increased risks have been reported for several cancer sites besides breast and ovary. As most of the families included…”
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Do Preferred Risk Formats Lead to Better Understanding? A Multicenter Controlled Trial on Communicating Familial Breast Cancer Risks Using Different Risk Formats by Henneman, Lidewij, van Asperen, Christi J, Oosterwijk, Jan C, Menko, Fred H, Claassen, Liesbeth, Timmermans, Daniëlle Rm

“…Counselees' preferences are considered important for the choice of risk communication format and for improving patient-centered care. We here report on…”
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Birt-Hogg-Dubé syndrome: diagnosis and management by Menko, Fred H, Dr, van Steensel, Maurice AM, MD, Giraud, Sophie, MD, Friis-Hansen, Lennart, MD, Richard, Stéphane, Prof, Ungari, Silvana, MD, Nordenskjöld, Magnus, Prof, Hansen, Thomas vO, MSc, Solly, John, PhD, Maher, Eamonn R, Prof

“…Summary Birt-Hogg-Dubé syndrome (BHD) is an autosomal dominant condition characterised clinically by skin fibrofolliculomas, pulmonary cysts, spontaneous…”
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Dysplastic changes in prophylactically removed Fallopian tubes of women predisposed to developing ovarian cancer by Piek, Jurgen M. J., van Diest, Paul J., Zweemer, Ronald P., Jansen, Jan W., Poort-Keesom, Ria J. J., Menko, Fred H., Gille, Johan J. P., Jongsma, Ans P. M., Pals, Gerard, Kenemans, Peter, Verheijen, René H. M.

“…The aim of this study was to investigate the occurrence of (pre)neoplastic lesions in overtly normal Fallopian tubes from women predisposed to developing…”
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Relative frequency and morphology of cancers in STK11 mutation carriers by Lim, Wendy, Olschwang, Sylviane, Keller, Josbert J., Westerman, Anne Marie, Menko, Fred H., Boardman, Lisa A., Scott, Rodney J., Trimbath, Jill, Giardiello, Francis M., Gruber, Stephen B., Gille, Johan J.P., Offerhaus, G.Johan A., de Rooij, Felix W.M., Wilson, J.H.Paul, Spigelman, Allan D., Phillips, Robin K.S., Houlston, Richard S.

“…Background & Aims: There is limited data on the spectrum and risk for cancer associated with germline serine/threonine protein kinase 11 ( STK11) mutations…”
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Large genomic deletions and duplications in the BRCA1 gene identified by a novel quantitative method by HOGERVORST, Frans B. L, NEDERLOF, Petra M, KLUIJT, Irma, DOMMERING, Charlotte, VERHOEF, Senno, SCHOUTEN, Jan P, VAN'T VEER, Laura J, PALS, Gerard, GILLE, Johan J. P, MCELGUNN, Cathal J, GRIPPELING, Maartje, PRUNTEL, Roelof, REGNERUS, Rein, VAN WELSEM, Tibor, VAN SPAENDONK, Resie, MENKO, Fred H

“…We applied a novel method to detect single or multiple exon deletions and amplifications in the BRCA1 gene. The test, called multiplex ligation-dependent probe…”
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MSH2 Mutation Carriers Are at Higher Risk of Cancer Than MLH1 Mutation Carriers: A Study of Hereditary Nonpolyposis Colorectal Cancer Families by VASEN, H. F. A, STORMORKEN, A, MENKO, F. H, NAGENGAST, F. M, KLEIBEUKER, J. H, GRIFFIOEN, G, TAAL, B. G, MOLLER, P, WIJNEN, J. T

“…Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant disease characterized by the clustering of colorectal cancer, endometrial cancer,…”
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Low penetrance of paraganglioma and pheochromocytoma in an extended kindred with a germline SDHB exon 3 deletion by Rijken, J.A., Niemeijer, N.D., Corssmit, E.P.M., Jonker, M.A., Leemans, C.R., Menko, F.H., Hensen, E.F.

“…In the Netherlands, the majority of hereditary paragangliomas (PGL) is caused by SDHD, SDHB and SDHAF2 mutations. Founder mutations in SDHD are particularly…”
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Absence of the Birt-Hogg-Dubé gene product is associated with increased hypoxia-inducible factor transcriptional activity and a loss of metabolic flexibility by Preston, R S, Philp, A, Claessens, T, Gijezen, L, Dydensborg, A B, Dunlop, E A, Harper, K T, Brinkhuizen, T, Menko, F H, Davies, D M, Land, S C, Pause, A, Baar, K, van Steensel, M A M, Tee, A R

“…Under conditions of reduced tissue oxygenation, hypoxia-inducible factor (HIF) controls many processes, including angiogenesis and cellular metabolism, and…”
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The role of mismatch repair gene defects in the development of adenomas in patients with HNPCC by De Jong, Andrea E, Morreau, Hans, Van Puijenbroek, Marjo, Eilers, Paul H c, Wijnen, Juul, Nagengast, Fokko M, Griffioen, Gerrit, Cats, Annemieke, Menko, Fred H, Kleibeuker, Jan H, Vasen, Hans F A

“…The adenoma-carcinoma sequence in hereditary nonpolyposis colorectal cancer (HNPCC) is accelerated. It remains unknown whether the mismatch repair (MMR) defect…”
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Multiplicity in polyp count and extracolonic manifestations in 40 Dutch patients with MYH associated polyposis coli (MAP) by Nielsen, M, Franken, P F, Reinards, T H C M, Weiss, M M, Wagner, A, van der Klift, H, Kloosterman, S, Houwing-Duistermaat, J J, Aalfs, C M, Ausems, M G E M, Bröcker-Vriends, A H J T, Gomez Garcia, E B, Hoogerbrugge, N, Menko, F H, Sijmons, R H, Verhoef, S, Kuipers, E J, Morreau, H, Breuning, M H, Tops, C M J, Wijnen, J T, Vasen, H F A, Fodde, R, Hes, F J

“…Objective: To investigate the contribution of MYH associated polyposis coli (MAP) among polyposis families in the Netherlands, and the prevalence of colonic…”
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Screening behavior of individuals at high risk for colorectal cancer by Bleiker, Eveline M.A., Menko, Fred H., Taal, Babs G., Kluijt, Irma, Wever, Lidwina D.V., Gerritsma, Miranda A., Vasen, Hans F.A., Aaronson, Neil K.

“…Background & Aims: Periodic colonoscopy is an effective means of reducing the incidence and mortality of colorectal cancer in individuals with a family history…”
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Perceiving cancer-risks and heredity-likelihood in genetic-counseling: how counselees recall and interpret BRCA 1/2-test results by Vos, J, Oosterwijk, JC, Gómez-García, E, Menko, FH, Jansen, AM, Stoel, RD, van Asperen, CJ, Tibben, A, Stiggelbout, AM

“…Vos J, Oosterwijk JC, Gómez‐García E, Menko FH, Jansen AM, Stoel RD, van Asperen CJ, Tibben A, Stiggelbout AM. Perceiving cancer‐risks and heredity‐likelihood…”
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Genomic deletions of MSH2 and MLH1 in colorectal cancer families detected by a novel mutation detection approach by GILLE, J. J. P, HOGERVORST, F. B. L, MCELGUNN, C. J, SCHOUTEN, J. P, MENKO, F. H, PALS, G, WIJNEN, J. Th, VAN SCHOOTEN, R. J, DOMMERING, C. J, MEIJER, G. A, CRAANEN, M. E, NEDERLOF, P. M, DE JONG, D

“…Hereditary non-polyposis colorectal cancer is an autosomal dominant condition due to germline mutations in DNA-mismatch-repair genes, in particular MLH1, MSH2…”
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Cancer risk in families with hereditary nonpolyposis colorectal cancer diagnosed by mutation analysis by Vasen, HF, Wijnen, JT, Menko, FH, Kleibeuker, JH, Taal, BG, Griffioen, G, Nagengast, FM, Meijers-Heijboer, EH, Bertario, L, Varesco, L, Bisgaard, ML, Mohr, J, Fodde, R, Khan, PM

“…BACKGROUND & AIMS: Hereditary nonpolyposis colorectal cancer is characterized by early-onset colorectal cancer and the occurrence of various other cancers. The…”
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Decision analysis in the surgical treatment of colorectal cancer due to a mismatch repair gene defect by de Vos tot Nederveen Cappel, W H, Buskens, E, van Duijvendijk, P, Cats, A, Menko, F H, Griffioen, G, Slors, J F, Nagengast, F M, Kleibeuker, J H, Vasen, H F A

“…Background: In view of the high risk of developing a new primary colorectal carcinoma (CRC), subtotal colectomy rather than segmental resection or…”
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Localization of a Breast Cancer Susceptibility Gene, BRCA2, to Chromosome 13q12-13 by Wooster, Richard, Neuhausen, Susan L., Mangion, Jonathan, Quirk, Yvette, Ford, Deborah, Collins, Nadine, Nguyen, Kim, Seal, Sheila, Tran, Thao, Averill, Diane, Fields, Patty, Marshall, Gill, Narod, Steven, Lenoir, Gilbert M., Lynch, Henry, Feunteun, Jean, Devilee, Peter, Cornelisse, Cees J., Menko, Fred H., Daly, Peter A., Ormiston, Wilma, McManus, Ross, Pye, Carole, Lewis, Cathryn M., Cannon-Albright, Lisa A., Peto, Julian, Bruce A. J. Ponder, Skolnick, Mark H., Easton, Douglas F., Goldgar, David E., Stratton, Michael R.

“…A small proportion of breast cancer, in particular those cases arising at a young age, is due to the inheritance of dominant susceptibility genes conferring a…”
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Childhood brain tumours due to germline bi-allelic mismatch repair gene mutations by Johannesma, PC, van der Klift, HM, van Grieken, NCT, Troost, D, te Riele, H, Jacobs, MAJM, Postma, TJ, Heideman, DAM, Tops, CMJ, Wijnen, JT, Menko, FH

“…Johannesma PC, van der Klift HM, van Grieken NCT, Troost D, te Riele H, Jacobs MAJM, Postma TJ, Heideman DAM, Tops CMJ, Wijnen JT, Menko FH. Childhood brain…”
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Survival after adjuvant 5‐FU treatment for stage III colon cancer in hereditary nonpolyposis colorectal cancer by de Vos tot Nederveen Cappel, Wouter H., Meulenbeld, Hielke J., Kleibeuker, Jan H., Nagengast, Fokko M., Menko, Fred H., Griffioen, Gerrit, Cats, Annemiek, Morreau, Hans, Gelderblom, Hans, Vasen, Hans F.A.

“…In vitro studies suggest that a deficient mismatch repair (MMR) system reduces 5‐Fluorouracil cytotoxicity. Colon cancer (CC) in hereditary nonpolyposis…”
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