Search Results - "Menicagli, Michele"
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New insights in the expression of stromal caveolin 1 in breast cancer spread to axillary lymph nodes
Published in Scientific reports (02-02-2021)“…Recent evidence suggests that a loss of expression of caveolin in the stromal compartment (sCav-1) of human invasive breast carcinoma (IBC) may be a predictor…”
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Doxycycline, an Inhibitor of Mitochondrial Biogenesis, Effectively Reduces Cancer Stem Cells (CSCs) in Early Breast Cancer Patients: A Clinical Pilot Study
Published in Frontiers in oncology (12-10-2018)“…Cancer stem cells (CSCs) have been implicated in tumor initiation, recurrence, metastatic spread and poor survival in multiple tumor types, breast cancers…”
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Tumor growth-arrest effect of tetrahydroquinazoline-derivative human topoisomerase II-alpha inhibitor in HPV-negative head and neck squamous cell carcinoma
Published in Scientific reports (21-04-2024)“…Oral malignancies continue to have severe morbidity with less than 50% long-term survival despite the advancement in the available therapies. There is a…”
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Identification of New Potential Prognostic and Predictive Markers in High-Grade Osteosarcoma Using Whole Exome Sequencing
Published in International journal of molecular sciences (01-06-2023)“…Conventional high-grade osteosarcoma (OS) is the most common primary cancer of bone and it typically affects the extremities of adolescents. OS has a complex…”
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Sedoheptulose Kinase SHPK Expression in Glioblastoma: Emerging Role of the Nonoxidative Pentose Phosphate Pathway in Tumor Proliferation
Published in International journal of molecular sciences (26-05-2022)“…Glioblastoma (GBM) is the most common form of malignant brain cancer and is considered the deadliest human cancer. Because of poor outcomes in this disease,…”
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CXCL12α/SDF‐1 from perisynaptic Schwann cells promotes regeneration of injured motor axon terminals
Published in EMBO molecular medicine (01-08-2017)“…The neuromuscular junction has retained through evolution the capacity to regenerate after damage, but little is known on the inter‐cellular signals involved…”
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Laser Capture Microdissection and RNA-Seq Analysis: High Sensitivity Approaches to Explain Histopathological Heterogeneity in Human Glioblastoma FFPE Archived Tissues
Published in Frontiers in oncology (07-06-2019)“…Laser capture microdissection (LCM) coupled with RNA-seq is a powerful tool to identify genes that are differentially expressed in specific histological tumor…”
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Innovative Approach to Isolate and Characterize Glioblastoma Circulating Tumor Cells and Correlation with Tumor Mutational Status
Published in International journal of molecular sciences (01-06-2023)“…Circulating tumor cells (CTCs) are one of the most important causes of tumor recurrence and distant metastases. Glioblastoma (GBM) has been considered…”
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Metabolic-imaging of human glioblastoma live tumors: A new precision-medicine approach to predict tumor treatment response early
Published in Frontiers in oncology (05-09-2022)“…Background Glioblastoma (GB) is the most severe form of brain cancer, with a 12-15 month median survival. Surgical resection, temozolomide (TMZ) treatment, and…”
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Mouse mammary tumour virus-like env nucleotide and p14 signal peptide are present in feline mammary carcinomas, but not in neoplastic or dysplastic canine mammary lesions
Published in PloS one (24-07-2018)“…Mouse mammary tumour virus-like (MMTV-like) is suspected to be involved in human breast cancer and it has been hypothesized that companion animals might have a…”
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Loss of c-KIT expression in thyroid cancer cells
Published in PloS one (16-03-2017)“…Papillary thyroid carcinoma is the most frequent histologic type of thyroid tumor. Few studies investigated the role of c-KIT expression in thyroid tumors,…”
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Granulocyte–macrophage colony-stimulating factor as an autocrine survival-growth factor in human gliomas
Published in Cytokine (Philadelphia, Pa.) (01-03-2012)“…We studied the expression of granulocyte–macrophage colony-stimulating factor (GM-CSF) and its receptors (GM-CSF.R) in 20 human brain gliomas with different…”
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Analysis of exosome-derived microRNAs reveals insights of intercellular communication during invasion of breast, prostate and glioblastoma cancer cells
Published in Cell adhesion & migration (01-01-2021)“…MiRNAs represent a mechanism that regulates gene expression in many pathological conditions. Exosomes are known to be secreted from all types of cells, and the…”
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Exploring Regorafenib Responsiveness and Uncovering Molecular Mechanisms in Recurrent Glioblastoma Tumors through Longitudinal In Vitro Sampling
Published in Cells (Basel, Switzerland) (01-03-2024)“…Glioblastoma, a deadly brain tumor, shows limited response to standard therapies like temozolomide (TMZ). Recent findings from the REGOMA trial underscore a…”
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Presence of a mouse mammary tumour virus-like in feline lymphomas: a preliminary study
Published in Infectious agents and cancer (23-06-2022)“…Abstract The mouse mammary tumour virus (MMTV) is implicated in the aetiology of murine mammary carcinomas and a variant of it, the type B leukemogenic virus,…”
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Association of Mouse Mammary Tumor Virus With Human Breast Cancer: Histology, Immunohistochemistry and Polymerase Chain Reaction Analyses
Published in Frontiers in oncology (07-05-2018)“…The purpose of this study is to determine whether mouse mammary tumor virus (MMTV)-associated human breast cancer has the same or similar histology to…”
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Pathological Features and Molecular Phenotype of MMTV Like-Positive Feline Mammary Carcinomas
Published in Animals (Basel) (27-09-2021)“…In the last few years MMTV-like nucleotide sequences were detected in some feline and canine mammary tumours. Due to the confirmed role of cats in the…”
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Single-Cell Molecular Characterization to Partition the Human Glioblastoma Tumor Microenvironment Genetic Background
Published in Cells (Basel, Switzerland) (26-03-2022)“…Glioblastoma (GB) is a devastating primary brain malignancy. The recurrence of GB is inevitable despite the standard treatment of surgery, chemotherapy, and…”
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Molecular portrait of a rare case of metastatic glioblastoma: somatic and germline mutations using whole-exome sequencing
Published in Neuro-oncology (Charlottesville, Va.) (01-02-2016)Get full text
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ANKRD44 Gene Silencing: A Putative Role in Trastuzumab Resistance in Her2-Like Breast Cancer
Published in Frontiers in oncology (26-06-2019)“…Trastuzumab is an effective therapeutic treatment for Her2-like breast cancer; despite this most of these tumors develop resistance to therapy due to specific…”
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