Search Results - "Menhali, Asma Al"
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2D nanostructures: Potential in diagnosis and treatment of Alzheimer’s disease
Published in Biomedicine & pharmacotherapy (01-01-2024)“…Two-dimensional (2D) nanomaterials have garnered enormous attention seemingly due to their unusual architecture and properties. Graphene and graphene oxide…”
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2
Probiotics Upregulate Trefoil Factors and Downregulate Pepsinogen in the Mouse Stomach
Published in International journal of molecular sciences (10-08-2019)“…Probiotics are used in the management of some gastrointestinal diseases. However, little is known about their effects on normal gastric epithelial biology. The…”
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Potential role of probiotics in the management of gastric ulcer
Published in Experimental and therapeutic medicine (01-07-2016)“…Gastric ulcer is one of the most common chronic gastrointestinal diseases characterized by a significant defect in the mucosal barrier. Helicobacter pylori (H…”
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4
A Narrative Role of Vitamin D and Its Receptor: With Current Evidence on the Gastric Tissues
Published in International journal of molecular sciences (05-08-2019)“…Vitamin D is a major steroid hormone that is gaining attention as a therapeutic molecule. Due to the general awareness of its importance for the overall…”
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Epimers of Vitamin D: A Review
Published in International journal of molecular sciences (11-01-2020)“…In this review, we discuss the sources, formation, metabolism, function, biological activity, and potency of C3-epimers (epimers of vitamin D). We also…”
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An LC-MS/MS Method for Analysis of Vitamin D Metabolites and C3 Epimers in Mice Serum: Oral Supplementation Compared to UV Irradiation
Published in Molecules (Basel, Switzerland) (26-08-2021)“…The most common forms of vitamin D in human and mouse serum are vitamin D3 and vitamin D2 and their metabolites. The aim of this study is to determine whether…”
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Seven-Month Vitamin D Deficiency Inhibits Gastric Epithelial Cell Proliferation, Stimulates Acid Secretion, and Differentially Alters Cell Lineages in the Gastric Glands
Published in Nutrients (01-11-2023)“…Vitamin D (VD) deficiency can result from insufficiency of either light exposure or VD intake. We investigated the biological effects of VD deficiency for 7…”
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Long-Term Vitamin D Deficiency Results in the Inhibition of Cell Proliferation and Alteration of Multiple Gastric Epithelial Cell Lineages in Mice
Published in International journal of molecular sciences (15-06-2022)“…Over one billion people globally are vitamin D (VD) deficient. Studies on the biological roles of VD are numerous but very little on the stomach. This project…”
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Overgrowth of Squamocolumnar Junction and Dysregulation of Stem Cell Lineages in the Stomach of Vitamin A-Deficient Mice
Published in Nutrients (01-08-2022)“…Junctional epithelia are common sites for pathological transformations. In mice, the stratified epithelium of the forestomach joins the simple glandular…”
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Gastrin induces parathyroid hormone-like hormone expression in gastric parietal cells
Published in American journal of physiology: Gastrointestinal and liver physiology (01-06-2017)“…Parietal cells play a fundamental role in stomach maintenance, not only by creating a pathogen-free environment through the production of gastric acid, but…”
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Modulation of Stem Cell Progeny by Probiotics during Regeneration of Gastric Mucosal Erosions
Published in Biology (Basel, Switzerland) (28-06-2021)“…Patients with gastric mucosal erosions are predisposed to chronic gastritis, ulcer or even cancer. The repair of mucosal erosions involves several events…”
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Vitamin D Is Necessary for Murine Gastric Epithelial Homeostasis
Published in Biology (Basel, Switzerland) (23-07-2021)“…Unlike other organs, the importance of VD in a normal stomach is unknown. This study focuses on understanding the physiological role of vitamin D in gastric…”
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Hip1r is expressed in gastric parietal cells and is required for tubulovesicle formation and cell survival in mice
Published in The Journal of clinical investigation (01-07-2008)“…Huntingtin interacting protein 1 related (Hip1r) is an F-actin- and clathrin-binding protein involved in vesicular trafficking. In this study, we demonstrate…”
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Application of a new vitamin D blood test on the Emirati population
Published in The Journal of steroid biochemistry and molecular biology (01-06-2018)“…[Display omitted] •An LC–MS/MS method was developed to quantify 10 vitamin D metabolites.•Our method can separate co-eluting inactive epimers and isobars from…”
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15
Gastrin regulation of parathyroid hormone like‐hormone (Pthlh) in gastric parietal cells
Published in The FASEB journal (01-04-2011)“…Although Pthlh is highly expressed in gastric tumors, its normal expression, function and regulation in the stomach are unknown. In this study we used…”
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Hypergastrinemia and hypertrophic gastritis in Hip1r‐deficient mice
Published in The FASEB journal (2007)“…Gastrin is a potent growth factor for the gastric mucosa, with hypergastrinemia resulting in increased proliferation of progenitor cells, and increased depth…”
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Loss of Parietal Cell Tubulovesicles and Hypertrophic Gastritis in Hip1r Knockout Mice
Published in The FASEB journal (01-03-2006)“…Huntingtin‐interacting protein‐1 related (Hip1r) is a clathrin and F‐actin binding protein proposed to play an important role in endocytosis. Hip1r is…”
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Parathyroid hormone-like hormone (PTHLH): A novel parietal cell growth factor regulated by gastrin
Published 01-01-2012“…Parietal cells play a fundamental role in stomach physiology, not only by creating a pathogen free environment through the production of gastric acid, but also…”
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